Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bernd Muellejans"'
Autor:
Bernd, Muellejans, Angel, López, Michael H, Cross, César, Bonome, Lachlan, Morrison, Andrew J T, Kirkham
Publikováno v:
Critical Care
Introduction This double-blind, randomized, multicentre study was conducted to compare the efficacy and safety of remifentanil and fentanyl for intensive care unit (ICU) sedation and analgesia. Methods Intubated cardiac, general postsurgical or medic
Publikováno v:
Critical Care. 10:R91
Remifentanil is an opioid with a unique pharmacokinetic profile. Its organ-independent elimination and short context-sensitive half time of 3 to 4 minutes lead to a highly predictable offset of action. We tested the hypothesis that with an analgesia-
Autor:
M. H. Cross, Andrew J T Kirkham, César Bonome, Lachlan M. M. Morrison, Angel López, Bernd Muellejans
Publikováno v:
Critical Care. 8:R1
This double-blind, randomized, multicentre study was conducted to compare the efficacy and safety of remifentanil and fentanyl for intensive care unit (ICU) sedation and analgesia. Intubated cardiac, general postsurgical or medical patients (aged ≥
Publikováno v:
Critical Care
Remifentanil HCl is a μ-opioid agonist which has an onset of action of about 1 min and rapidly achieves steady-state. Metabolism by non-specific blood and tissue esterases results in a terminal half-life of < 10 min which is independent of the durat