Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bernd Lecher"'
Publikováno v:
Translational Neuroscience, Vol 8, Iss 1, Pp 211-224 (2017)
Translational Neuroscience
Translational Neuroscience
The objective of this study was to evaluate the piglet and the mouse as model systems for preterm cortical development. According to the clinical context, we used non invasive EEG recordings. As a prerequisite, we developed miniaturized Ag/AgCl elect
Publikováno v:
Biological chemistry. 394(9)
Contact to polyanions induces autoactivation of the serine protease factor XII that triggers the kallikrei-kinin system. Recent studies indicate that polysaccharide-induced autoactivation of factor XII has a role in allergy-related vascular leakage,
Autor:
Reinhard Sedlmeier, Jenny Björkqvist, Peter Burfeind, Thomas Tradler, Werner Müller-Esterl, Walter A. Wuillemin, Bernd Lecher, Thomas Renné, Chris Oschatz, Gunnar Nilsson, Sven Hammerschmidt, Thomas Jansen, Coen Maas, Sven Cichon
Publikováno v:
Immunity. (2):258-268
SummaryActivated mast cells trigger edema in allergic and inflammatory disease. We report a paracrine mechanism by which mast cell-released heparin increases vascular permeability in vivo. Heparin activated the protease factor XII, which initiates br