Výsledky vyhledávání - "Bernd Kazmierczak"

Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa

Autor: Gian Kayser, Torsten Goldmann, Bernd Kazmierczak, Klaus Kayser, Ekkehard Vollmer, Zdravko Kosjerina

Publikováno v: Lung Cancer. 47:205-214

This article analyzes phenotype and genotype alterations of the lung in association with lung cancer. The frequency of phenotype preneoplastic lesions (atypical adenomatoid hyperplasia (AAH) and squamous cell dysplasia (SCD)) was analyzed at distinct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31056e2d321f3354e0a7c7a52414692b
https://doi.org/10.1016/j.lungcan.2004.07.042

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Chromosomal Aberrations, Profiles of Expression of Growth-related Markers Including Galectins and Environmental Hazards in Relation to the Incidence of Chondroid Pulmonary Hamartomas

Autor: Bernd Kazmierczak, Yehiel Zick, Klaus Kayser, Herbert Kaltner, Jörn Bullerdiek, Delia Dünnwald, Hans-Joachim Gabius, Sabine André

Publikováno v: Pathology - Research and Practice. 199:589-598

This prospective study includes 103 cases of chondroid pulmonary hamartomas, resected over a period of nearly six years. Genes encoding proteins of the high motility group (HMGI-C, (Y), chromosomes 12q15 and 6p21) were analyzed cytogenetically. Furth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7bfd1131f350097cb187dbbd6cd3b0
https://doi.org/10.1078/0344-0338-00466

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An identicalHMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with t(3;12)(q27-28;q14-15)

Autor: Inga Lemke, Jörn Bullerdiek, Bernd Kazmierczak, Piere Rogalla

Publikováno v: Genes, Chromosomes and Cancer. 29:363-366

The high frequency of the t(3;12)(q27–28;q14–15) in lipomas and pulmonary chondroid hamartomas (PCHs) makes the HMGIC-LPP fusion gene the most common fusion gene in a human tumor known so far. Nevertheless, there is no in-depth molecular analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd7934986afda70f40fc902adfa2a055
https://doi.org/10.1002/1098-2264(2000)9999:9999<1::aid-gcc1043>3.0.co

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A high frequency of tumors with rearrangements of genes of the HMGI(Y) family in a series of 191 pulmonary chondroid hamartomas

Autor: Ilse Breightman, Bernd Kazmierczak, Werner Wöckel, Sabine Bartnitzke, Kerstin Meyer-Bolte, Jörn Bullerdiek, Kim Hue Tran, Jens Rosigkeit

Publikováno v: Genes, Chromosomes and Cancer. 26:125-133

Pulmonary chondroid hamartomas (PCHs) are benign mesenchymal tumors that often are characterized by specific chromosomal aberrations. Herein we report our cytogenetic and molecular cytogenetic (FISH) studies on 191 PCHs, including 48 previously publi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1960461227c41af0d6694784b40cca
https://doi.org/10.1002/(sici)1098-2264(199910)26:2<125::aid-gcc4>3.0.co

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Amplification and expression of theHMGIC gene in a benign endometrial polyp

Autor: Jã¶rn Bullerdiek, Paola Dal Cin, Giovanni Tallini, Herman Van den Berghe, S. Wanschura, Philippe Moerman, Angelo Paolo Dei Tos, Bernd Kazmierczak, Ivo Van den Berghe

Publikováno v: Genes, Chromosomes and Cancer. 22:95-99

In a totally benign endometrial polyp, double minute chromosomes were shown to contain an amplified and apparently nonrearranged HMGIC gene, expressed in the tumor cells, suggesting amplification of HMGIC through double minute chromosome formation as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::530e3e260455ac2f35e8d489f5fc4e6b
https://doi.org/10.1002/(sici)1098-2264(199806)22:2<95::aid-gcc2>3.0.co

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The t(3;12)(q27;q14-q15) with underlyingHMGIC-LPP fusion is not determining an adipocytic phenotype

Autor: Bernd Kazmierczak, Piere Rogalla, Jörn Bullerdiek, Kerstin Meyer-Bolte, Kim Hue Tran

Publikováno v: Genes, Chromosomes and Cancer. 22:100-104

The HMGIC gene, located in chromosome band 12q15, is rearranged in many different benign human tumors, often resulting in its fusion to ectopic sequences from other genes. The t(3;12)(q27;q14-q15) fuses HMGIC with the LPP gene and has so far been des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20809a2b15d1cef7ea34ea632fd21955
https://doi.org/10.1002/(sici)1098-2264(199806)22:2<100::aid-gcc3>3.0.co

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Expression ofHMGI-C, a member of the high mobility group protein family, in a subset of breast cancers: Relationship to histologic grade

Autor: Jörn Bullerdiek, Ulrich Bonk, Klaus Drechsler, Bernd Kazmierczak, Volkhard Rippe, Piere Rogalla

Publikováno v: Molecular Carcinogenesis. 19:153-156

The high-mobility-group (HMG) protein gene HMGI-C is apparently involved in the genesis of a variety of benign human solid tumors with rearrangements of chromosomal region 12q14-15 affecting the HMGI-C gene. So far, no expression of HMGI-C has been f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f258e4bd1334b182049181609dc89ab
https://doi.org/10.1002/(sici)1098-2744(199707)19:3<153::aid-mc2>3.0.co

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Molecular cytogenetic characterization of del(7q) in two uterine leiomyoma-derived cell lines

Autor: R. Vanni, Paola Dal Cin, Gabriele Senger, Eric F.P.M. Schoenmakers, Susanna Marras, Bernd Kazmierczak, Herman Van den Berghe, Wim J.M. Van de Ven, Jörn Bullerdiek

Publikováno v: Genes, Chromosomes and Cancer. 18:155-161

Uterine leiomyoma cytogenetically exhibits at least six chromosomally abnormal subgroups. The largest subgroup is characterized by deletions of the long arm of chromosome 7. Few molecular and fluorescence in situ hybridization data are available that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19089a89a3c44c3ab80964995f83c451
https://doi.org/10.1002/(sici)1098-2264(199703)18:3<155::aid-gcc1>3.0.co

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HMGI-C, a Member of the High Mobility Group Family of Proteins, is Expressed in Hematopoietic Stem Cells and in Leukemic Cells

Autor: Piere Rogalla, Jürgen Wolf, Birgit Rommel, Jörn Bullerdiek, Andrea Jox, Bernd Kazmierczak, Christoph von Kalle

Publikováno v: Leukemia & Lymphoma. 26:603-607

The human HMGI-C gene encoding a member of the high mobility group protein family normally is expressed only during embryonic/fetal development but in none of the adult tissues tested so far. Recently, the HMGI-C gene has attracted a lot of interest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33279d80e50a91de636a3f13d54ca426
https://doi.org/10.3109/10428199709050896

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Transcriptional activation of HMGI-C in three pulmonary hamartomas each with a der(14) t(12; 14) as the sole cytogenetic abnormality

Autor: S. Wanschura, Sabine Bartnitzke, Bernd Kazmierczak, W.J.M. Van de Ven, Kerstin Meyer-Bolte, Y. Pohnke, Jörn Bullerdiek

Publikováno v: Cancer Letters. 102:17-21

Aberrations involving the chromosomal region 12q14-15 are non-random cytogenetic abnormalities in many benign tumors, e.g. pulmonary chondroid hamartomas (PCH). Recently, we identified rearrangements of the HMGI-C gene within the third or fourth intr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81383d457231eae25e0eb07807672ed4
https://doi.org/10.1016/0304-3835(96)04144-4

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