Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Bernd J Pichler"'
Autor:
Jaclyn Sceneay, Christoph M Griessinger, Sabrina H L Hoffmann, Shu Wen Wen, Christina S F Wong, Sophie Krumeich, Manfred Kneilling, Bernd J Pichler, Andreas Möller
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196040 (2018)
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid progenitor cells that are expanded in cancer and act as potent suppressors of the anti-tumor immune response. MDSCs consist of two major subsets, namely monoc
Externí odkaz:
https://doaj.org/article/f903317873e640e2b381237398744b27
Autor:
Desiree I. Frecot, Simone Blaess, Teresa R. Wagner, Philipp D. Kaiser, Bjoern Traenkle, Madeleine Fandrich, Meike Jakobi, Armin M. Scholz, Stefan Nueske, Nicole Schneiderhan-Marra, Cécile Gouttefangeas, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeHuman OX40 (hOX40/CD134), a member of the TNF receptor superfamily, is mainly expressed on activated T lymphocytes. Triggered by its ligand OX40L (CD252), it provides costimulatory signals that support the differentiation, proliferation and lo
Externí odkaz:
https://doaj.org/article/ce3a8aa1d9c443469359f03d31106fa0
Autor:
Stefan Wiehr, Anna-Maria Rolle, Philipp Warnke, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Gerald Reischl, Ingo B Autenrieth, Bernd J Pichler, Stella E Autenrieth
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164163 (2016)
Most frequently, gram-negative bacterial infections in humans are caused by Enterobacteriaceae and remain a major challenge in medical diagnostics. We non-invasively imaged moderate and severe systemic Yersinia enterocolitica infections in mice using
Externí odkaz:
https://doaj.org/article/c3d51fba8b154c8184aa1fcd70ef2cd1
Autor:
Federica Bonanno, Ran Sing Saw, Daniel Bleher, Ioannis Papadopoulos, Gregory D. Bowden, Kaare Bjerregaard-Andersen, Albert D. Windhorst, Bernd J. Pichler, Kristina Herfert, Andreas Maurer
Publikováno v:
ACS Omega, Vol 9, Iss 23, Pp 24774-24788 (2024)
Externí odkaz:
https://doaj.org/article/bded1bd3bd34484c848df899721fc131
Autor:
Marilena Poxleitner, Sabrina H. L. Hoffmann, Georgy Berezhnoy, Tudor M. Ionescu, Irene Gonzalez-Menendez, Florian C. Maier, Dominik Seyfried, Walter Ehrlichmann, Leticia Quintanilla-Martinez, Andreas M. Schmid, Gerald Reischl, Christoph Trautwein, Andreas Maurer, Bernd J. Pichler, Kristina Herfert, Nicolas Beziere
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-29 (2024)
Abstract Diet-induced increase in body weight is a growing health concern worldwide. Often accompanied by a low-grade metabolic inflammation that changes systemic functions, diet-induced alterations may contribute to neurodegenerative disorder progre
Externí odkaz:
https://doaj.org/article/67e4f3a5099d4da3aa33f787295c7a78
Autor:
Dominik Sonanini, Johannes Schwenck, Simone Blaess, Julia Schmitt, Andreas Maurer, Walter Ehrlichmann, Malte Ritter, Julia Skokowa, Manfred Kneilling, Gundram Jung, Falko Fend, Simon Krost, Christian M. Seitz, Peter Lang, Gerald Reischl, Rupert Handgretinger, Christian la Fougère, Bernd J. Pichler
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract Cell- and antibody-based CD19-directed therapies have demonstrated great potential for treating B-cell non-Hodgkin lymphoma (B-NHL). However, all these approaches suffer from limited response rates and considerable toxicity. Until now, thera
Externí odkaz:
https://doaj.org/article/4976f3f87c4446a5acbfe8a9bcce0cd4
Autor:
Moritz Mahling, Kerstin Fuchs, Wolfgang M Thaiss, Florian C Maier, Martina Feger, Daniel Bukala, Maren Harant, Martin Eichner, Jörg Reutershan, Florian Lang, Gerald Reischl, Bernd J Pichler, Manfred Kneilling
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124665 (2015)
CT26 colon carcinoma-bearing mice were anesthetized with isoflurane (IF) or ketamine/xylazine (KX) while breathing air or oxygen (O2). We performed 10 min static PET scans 1 h, 2 h and 3 h after [18F]FAZA injection and calculated the [18F]FAZA-uptake
Externí odkaz:
https://doaj.org/article/58d0a050fd0b4fea94f3e0ed7b4649c8
Autor:
Stefanie Nittka, Marcel A Krueger, John E Shively, Hanne Boll, Marc A Brockmann, Fabian Doyon, Bernd J Pichler, Michael Neumaier
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106921 (2014)
PurposeColorectal cancer is one of the most common forms of cancer, and the development of novel tools for detection and efficient treatment of metastases is needed. One promising approach is the use of radiolabeled antibodies for positron emission t
Externí odkaz:
https://doaj.org/article/f4d8f5b6c107497e9e59e53fde960aa2
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Adriana Di Nanni, Ran Sing Saw, Umberto M. Battisti, Gregory D. Bowden, Adam Boeckermann, Kaare Bjerregaard-Andersen, Bernd J. Pichler, Kristina Herfert, Matthias M. Herth, Andreas Maurer
Publikováno v:
ACS Omega, Vol 8, Iss 34, Pp 31450-31467 (2023)
Externí odkaz:
https://doaj.org/article/603f0f74c8804caf80aecf51268c6bb4