Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Bernd Bodenmiller"'
Autor:
Spencer S. Watson, Benoit Duc, Ziqi Kang, Axel de Tonnac, Nils Eling, Laure Font, Tristan Whitmarsh, Matteo Massara, iMAXT Consortium, Bernd Bodenmiller, Jean Hausser, Johanna A. Joyce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The tumor microenvironment plays a crucial role in determining response to treatment. This involves a series of interconnected changes in the cellular landscape, spatial organization, and extracellular matrix composition. However, assessing
Externí odkaz:
https://doaj.org/article/eaf2eec4622b451e8d2ad39be042dd33
Autor:
Stefanie Kirchberger, Mohamed R. Shoeb, Daria Lazic, Andrea Wenninger-Weinzierl, Kristin Fischer, Lisa E. Shaw, Filomena Nogueira, Fikret Rifatbegovic, Eva Bozsaky, Ruth Ladenstein, Bernd Bodenmiller, Thomas Lion, David Traver, Matthias Farlik, Christian Schöfer, Sabine Taschner-Mandl, Florian Halbritter, Martin Distel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Neutrophils are evolutionarily conserved innate immune cells playing pivotal roles in host defense. Zebrafish models have contributed substantially to our understanding of neutrophil functions but similarities to human neutrophil maturation
Externí odkaz:
https://doaj.org/article/25da6029f28242b39dcae2b849a07a2d
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Highly multiplexed imaging enables single-cell-resolved detection of numerous biological molecules in their spatial tissue context. Interactive visualization of multiplexed imaging data is crucial at any step of data analysis to f
Externí odkaz:
https://doaj.org/article/2c7a9adba09d4aaea9f35459784eb874
Autor:
Stefanie Hiltbrunner, Lena Cords, Sabrina Kasser, Sandra N. Freiberger, Susanne Kreutzer, Nora C. Toussaint, Linda Grob, Isabelle Opitz, Michael Messerli, Martin Zoche, Alex Soltermann, Markus Rechsteiner, Maries van den Broek, Bernd Bodenmiller, Alessandra Curioni-Fontecedro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Immune checkpoint inhibitor treatment has the potential to prolong survival in non-small cell lung cancer (NSCLC), however, some of the patients develop resistance following initial response. Here, we analyze the immune phenotype of matching
Externí odkaz:
https://doaj.org/article/c99e4e76f6b544649dae1c58e4b5b5c4
Autor:
Lena Cords, Sandra Tietscher, Tobias Anzeneder, Claus Langwieder, Martin Rees, Natalie de Souza, Bernd Bodenmiller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Cancer-associated fibroblasts (CAFs) are a diverse cell population within the tumour microenvironment, where they have critical effects on tumour evolution and patient prognosis. To define CAF phenotypes, we analyse a single-cell RNA sequenc
Externí odkaz:
https://doaj.org/article/e895f82d4db8449c83560249a1b3faa7
Autor:
Sandra Tietscher, Johanna Wagner, Tobias Anzeneder, Claus Langwieder, Martin Rees, Bettina Sobottka, Natalie de Souza, Bernd Bodenmiller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
T cell exhaustion in breast tumours remains to be fully characterised. Here, single cell transcriptomics and imaging mass cytometry analysis of luminal breast tumours with or without exhausted T cells suggests distinct patterns of PD-1 and CXCL13 exp
Externí odkaz:
https://doaj.org/article/08f5d97e823a4685b87f430c9ee08e84
Multiplexed single-cell imaging to characterize melanoma brain metastases under therapeutic pressure
Autor:
Stefanos Voglis, Nils Eling, Emilie Le Rhun, Mitchell Levesque, Michael Weller, Luca Regli, Bernd Bodenmiller
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101859- (2023)
Externí odkaz:
https://doaj.org/article/95faeed4770e48bbb068a40eb9c87d22
Autor:
Eduardo A. González-Solares, Ali Dariush, Carlos González-Fernández, Aybüke Küpcü Yoldaş, Alireza Molaeinezhad, Mohammad Al Sa’d, Leigh Smith, Tristan Whitmarsh, Neil Millar, Nicholas Chornay, Ilaria Falciatori, Atefeh Fatemi, Daniel Goodwin, Laura Kuett, Claire M. Mulvey, Marta Páez Ribes, Fatime Qosaj, Andrew Roth, Ignacio Vázquez-García, Spencer S. Watson, Jonas Windhager, Samuel Aparicio, Bernd Bodenmiller, Ed Boyden, Carlos Caldas, Owen Harris, Sohrab P. Shah, Simon Tavaré, CRUK IMAXT Grand Challenge Team, Dario Bressan, Gregory J. Hannon, Nicholas A. Walton
Publikováno v:
Biological Imaging, Vol 3 (2023)
With the aim of producing a 3D representation of tumors, imaging and molecular annotation of xenografts and tumors (IMAXT) uses a large variety of modalities in order to acquire tumor samples and produce a map of every cell in the tumor and its host
Externí odkaz:
https://doaj.org/article/261a693a1fbf4e838527c973f854d805
Autor:
Johanna Wagner, Markus Masek, Andrea Jacobs, Charlotte Soneson, Sujana Sivapatham, Nicolas Damond, Natalie de Souza, Mark D. Robinson, Bernd Bodenmiller
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-16 (2022)
Measurement(s) RNA-seq gene expression profiling assay • cell surface proteins • protein expression at the single-cell level • Epithelial-to-Mesenchymal Transition • breast cancer cell • mammary gland epithelial cell Technology Type(s) mRNA
Externí odkaz:
https://doaj.org/article/81a2b53781e4443a83618d3a2b4f6b3d
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101578- (2022)
Summary: With mass and flow cytometry, millions of single-cell profiles with dozens of parameters can be measured to comprehensively characterize complex tumor ecosystems. Here, we present scQUEST, an open-source Python library for cell type identifi
Externí odkaz:
https://doaj.org/article/9ed522bbfd0644ff9c5ff13479e91575