Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bernd Bühler"'
Autor:
Andreas Hafer, Bernd Bühler
Von den ersten Anfängen bei Thales und Pythagoras im antiken Griechenland über Newton und Darwin bis zur heutigen modernen Quantenmechanik und Genmanipulation haben die Naturwissenschaften einen fast dreitausendjährigen Weg hinter sich gebracht. D
Publikováno v:
Gene Therapy. 13:1480-1492
CCR5 is the chemokine co-receptor for R5-tropic human immunodeficiency virus type 1 (HIV-1) isolates most often associated with primary infection. We have developed an HIV-1 self-inactivating vector, CAD-R5, containing a CCR5 single-chain antibody (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7b71c45a5ca29e939806e11b179666
https://doi.org/10.1038/sj.gt.3302801
https://doi.org/10.1038/sj.gt.3302801
Publikováno v:
OECD Journal on Budgeting. 1:7-34
Over the last two decades, the focus of public sector budgeting and management in most OECD Member countries has changed from inputs towards outputs. While important elements of an input-based management approach remain, many managers are now more of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df2d61f686ccefa00d4a8e3a5d2fb7e
https://doi.org/10.1787/budget-v1-art20-en
https://doi.org/10.1787/budget-v1-art20-en
Autor:
Arthur J. Olson, Bernd Bühler, Chi-Huey Wong, John H. Elder, Garrett M. Morris, Ying-Chuan Lin, Bruce E. Torbett, Douglas D. Richman
Publikováno v:
Journal of Virology. 75:9502-9508
TL-3 is a protease inhibitor developed using the feline immunodeficiency virus protease as a model. It has been shown to efficiently inhibit replication of human, simian, and feline immunodeficiency viruses and therefore has broad-based activity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e647a0d182f8483322998f002c9a55d
https://doi.org/10.1128/jvi.75.19.9502-9508.2001
https://doi.org/10.1128/jvi.75.19.9502-9508.2001
Autor:
Rolf Tünnemann, Bernd Bühler, Günter Gauglitz, Hans-Peter Fiedler, Wolfgang Wohlleben, Karl-Heinz Wiesmüller, Martin Mehlmann, Roderich D. Süssmuth, Stefan Pelzer, Günther Jung
Publikováno v:
Analytical Chemistry. 73:4313-4318
This paper describes the design, characterization, and use of an optical biosensor suited for the process control of biotechnological processes. The detector principle is based on reflectometric interference spectroscopy (RIfS). RIfS enables a label-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223a93f84ba8fee35a5605eff2aac252
https://doi.org/10.1021/ac010270f
https://doi.org/10.1021/ac010270f
Publikováno v:
Proceedings of the National Academy of Sciences. 97:805-810
Studies of naturally occurring polymorphisms of the CCR5 gene have shown that deletion of the functional receptor or reduced expression of the gene can have beneficial effects in preventing HIV-1 infection or delaying disease. Because these polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae0dad0fe5242a5afc539a6a8e1b3e2
https://doi.org/10.1073/pnas.97.2.805
https://doi.org/10.1073/pnas.97.2.805
Autor:
Manuel Sanchez-Alavez, Nicholas W. Henriksen, Howard S. Fox, Bernd Bühler, Mboya Burudi, Danica L. Lerner, John H. Elder, Ying-Chuan Lin, Salvador Huitron-Resendiz, Sohela de Rozières, Bruce E. Torbett, Steven J. Henriksen
Publikováno v:
Journal of virology. 78(9)
In vivo tests were performed to assess the influence of the protease inhibitor TL-3 on feline immunodeficiency virus (FIV)-induced central nervous system (CNS) deficits. Twenty cats were divided into four groups of five animals each. Group 1 received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd04089eb867efed5ed6d7f818ab12e
https://pubmed.ncbi.nlm.nih.gov/15078933
https://pubmed.ncbi.nlm.nih.gov/15078933
Publikováno v:
Immunogenetics. 42
The severe combined immunodeficiency (scid) mutation affects both coding joint formation during immunoglobulin and T-cell receptor V(D)J recombination and double-strand break repair. We analyzed scid cells for their ability to undergo other types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3214b22bd422c8c65c2d10db13ded35a
https://doi.org/10.1007/bf00191223
https://doi.org/10.1007/bf00191223
Publikováno v:
Journal of immunological methods. 175(2)
Episomal vectors have been developed which are useful for studying V(D)J recombination both after transient transfections and in stably transfected cells. In contrast to recombination substrates previously described for transient assays, rearrangemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5626b79da9211956475b7dde168323cb
https://pubmed.ncbi.nlm.nih.gov/7930653
https://pubmed.ncbi.nlm.nih.gov/7930653
Publikováno v:
Blood. 104:1755-1755
The molecular mechanism of human immunodeficiency virus type 1 (HIV-1) entry into target cells is a multistep mechanism. The viral envelope glycoproteins (env) binds first to CD4 and subsequently interacts with the V3 loop with a chemokine receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf720f5db0e53b3a781b2ef871660035
https://doi.org/10.1182/blood.v104.11.1755.1755
https://doi.org/10.1182/blood.v104.11.1755.1755