Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bernd, Jagla"'
Autor:
Célia Raïs, Daniela Gaspar Santos, Giulia Sansone, Stéphane Blanchard, Jean-Pierre Bourgeois, Bernd Jagla, Baptiste Saudemont, Laurène Schlick, Stéphanie Pons, Uwe Maskos
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Human induced pluripotent stem cells (hiPSCs) have been used extensively in vitro to model early events in neurodevelopment. Because of a number of shortcomings, previous work has established a potential to use these cells in vivo after transplantati
Externí odkaz:
https://doaj.org/article/e36c19e1b9ef41d1a6d6d7bc646fb362
Autor:
Tui Neri, Emilye Hiriart, Patrick P. van Vliet, Emilie Faure, Russell A. Norris, Batoul Farhat, Bernd Jagla, Julie Lefrancois, Yukiko Sugi, Thomas Moore-Morris, Stéphane Zaffran, Randolph S. Faustino, Alexander C. Zambon, Jean-Pierre Desvignes, David Salgado, Robert A. Levine, Jose Luis de la Pompa, André Terzic, Sylvia M. Evans, Roger Markwald, Michel Pucéat
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
There are few human models that can recapitulate valve development in vitro. Here, the authors derive human pre-valvular endocardial cells (HPVCs) from iPSCs and show they can recapitulate early valvulogenesis, and patient derived HPVCs have features
Externí odkaz:
https://doaj.org/article/e45f606ce5c6400ca0225b4e0d2ad5be
Autor:
Michael D Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C Marioni
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008686 (2020)
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis. However, this targeted approach has to date been una
Externí odkaz:
https://doaj.org/article/9e894bb2de694ec2a6fa46dde30a8111
Autor:
Evelyne Krin, Sebastian Aguilar Pierlé, Odile Sismeiro, Bernd Jagla, Marie-Agnès Dillies, Hugo Varet, Oihane Irazoki, Susana Campoy, Zoé Rouy, Stéphane Cruveiller, Claudine Médigue, Jean-Yves Coppée, Didier Mazel
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding bo
Externí odkaz:
https://doaj.org/article/ff6e123344e44f07b716a0fc17bc873f
Publikováno v:
Microbial Cell, Vol 5, Iss 4, Pp 169-183 (2018)
Genetic and molecular studies have indicated that an epigenetic imprint at mat1, the sexual locus of fission yeast, initiates mating type switching. The polar DNA replication of mat1 generates an imprint on the Watson strand. The process by which the
Externí odkaz:
https://doaj.org/article/30e55ec3b1554fb5abe6c3986680a57b
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006917 (2018)
The success of Staphylococcus aureus, as both a human and animal pathogen, stems from its ability to rapidly adapt to a wide spectrum of environmental conditions. Two-component systems (TCSs) play a crucial role in this process. Here, we describe a n
Externí odkaz:
https://doaj.org/article/9e464733822c4116a533391ddc1762b7
Autor:
Batoul Farhat, Ignacio Bordeu, Bernd Jagla, Hugo Blanc, Karine Loulier, Benjamin D. Simons, Emmanuel Beaurepaire, Jean Livet, Michel Pucéat
Congenital heart malformations often include mitral valve defects which remain largely unexplained. During embryogenesis, a restricted population of endocardial cells within the atrioventricular canal (AVC) undergoes endothelial to mesenchymal transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3079092c9331f99025e20da60d4e7ae
https://doi.org/10.1101/2022.08.06.503022
https://doi.org/10.1101/2022.08.06.503022
Autor:
Raul Y Sanchez David, Chantal Combredet, Odile Sismeiro, Marie-Agnès Dillies, Bernd Jagla, Jean-Yves Coppée, Marie Mura, Mathilde Guerbois Galla, Philippe Despres, Frédéric Tangy, Anastassia V Komarova
Publikováno v:
eLife, Vol 5 (2016)
The RIG-I-like receptors (RLRs) play a major role in sensing RNA virus infection to initiate and modulate antiviral immunity. They interact with particular viral RNAs, most of them being still unknown. To decipher the viral RNA signature on RLRs duri
Externí odkaz:
https://doaj.org/article/3898575afa66487393e909428ea9971f
Autor:
Bernd, Jagla, Valentina, Libri, Claudia, Chica, Vincent, Rouilly, Sebastien, Mella, Michel, Puceat, Milena, Hasan
Publikováno v:
Journal of Immunological Methods
Journal of Immunological Methods, 2021, 499, pp.113176. ⟨10.1016/j.jim.2021.113176⟩
Journal of Immunological Methods, Elsevier, 2021, 499, pp.113176. ⟨10.1016/j.jim.2021.113176⟩
Journal of Immunological Methods, 2021, 499, pp.113176. ⟨10.1016/j.jim.2021.113176⟩
Journal of Immunological Methods, Elsevier, 2021, 499, pp.113176. ⟨10.1016/j.jim.2021.113176⟩
International audience; Single-cell RNA-sequencing (scRNAseq) experiments are becoming a standard tool for bench-scientists to explore the cellular diversity present in all tissues. Data produced by scRNAseq is technically complex and requires analyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03955fea63d550da2340b9fe6660c56e
https://hal-pasteur.archives-ouvertes.fr/pasteur-03478264
https://hal-pasteur.archives-ouvertes.fr/pasteur-03478264
Autor:
Jonathan T. Butcher, David J. Milan, Emily J. Farrar, David S. Peal, Emilye Hiriart, Ablajan Mahmut, Michel Pucéat, Bernd Jagla
Publikováno v:
Science Advances
Science Advances, 2021, 7 (45), pp.eabf7910. ⟨10.1126/sciadv.abf7910⟩
Science Advances, 2021, 7 (45), pp.eabf7910. ⟨10.1126/sciadv.abf7910⟩
Description
Cell reprogramming is at the origin of valve calcification.
Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells revert to an embryonic-like na
Cell reprogramming is at the origin of valve calcification.
Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells revert to an embryonic-like na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab35d94da46fd4aaf418e0ae93d1d5fb
https://pubmed.ncbi.nlm.nih.gov/34739324
https://pubmed.ncbi.nlm.nih.gov/34739324