Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Bernd, Echtenacher"'
Autor:
Lisa Schindler, Jutta Moosbauer, Daniel Schmidt, Thilo Spruss, Lukas Grätz, Steffen Lüdeke, Frank Hofheinz, Sebastian Meister, Bernd Echtenacher, Günther Bernhardt, Jens Pietzsch, Dirk Hellwig, Max Keller
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4922
Cancers 14(2022), 4922
Cancers 14(2022), 4922
Overexpression of the neurotensin receptor type 1 (NTS1R), a peptide receptor located at the plasma membrane, has been reported for a variety of malignant tumors. Thus, targeting the NTS1R with 18F- or 68Ga-labeled ligands is considered a straightfor
Autor:
Sebastian Bittner, Brigitte Ruhland, Veronika Hofmann, Lisa Schmidleithner, Kathrin Schambeck, Asmita Pant, Philipp Stüve, Michael Delacher, Bernd Echtenacher, Matthias Edinger, Petra Hoffmann, Michael Rehli, Claudia Gebhard, Nicholas Strieder, Thomas Hehlgans, Markus Feuerer
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Engineered regulatory T cell (Treg cell) therapy is a promising strategy to treat patients suffering from inflammatory diseases, autoimmunity, and transplant rejection. However, in many cases, disease-related antigens that can be targeted by Treg cel
Autor:
Lena Feuerer, David Stieglitz, Bernd Echtenacher, Claus Hellerbrand, Sigrid Karrer, Simone Braig, Anja-Katrin Bosserhoff, Peter Dietrich, Stephanie Arndt, Susanne Lamm, Silke Kuphal
Publikováno v:
Oncogene. 38:609-621
Melanoma is the deadliest form of skin cancer with rising incidence, creating a significant health problem. We discovered increased expression of bone morphogenetic protein 6 (BMP6) in melanoma cells and tissues, and observed that BMP6 deficiency cau
Autor:
Andrea Kotz, Johannes Wagener, Jakob Engel, Françoise H Routier, Bernd Echtenacher, Ilse Jacobsen, Jürgen Heesemann, Frank Ebel
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15729 (2010)
The mannosyltransferase Och1 is the key enzyme for synthesis of elaborated protein N-glycans in yeast. In filamentous fungi genes implicated in outer chain formation are present, but their function is unclear. In this study we have analyzed the Och1
Externí odkaz:
https://doaj.org/article/908e669e996b449b8ad8a101bbf51de2
Autor:
F Bitterer, Christian Stroszczynski, Ernst-Michael Jung, A. K. Wege, P. Hoffmann, K. Schardt, Bernd Echtenacher, Sebastian Gehmert
Publikováno v:
Ultraschall in der Medizin - European Journal of Ultrasound. 37:277-282
Purpose: A. fumigatus infections represent a major threat for patients with a suppressed immune system. Early diagnosis is of importance for a favorable outcome but appears to be difficult due to limited diagnostic procedures. Here we investigated th
Autor:
Matthias Edinger, Matthias Grube, Bernd Echtenacher, Juergen Loeffler, Bernd Krüger, Petra Hoffmann, Markus Mezger, Ernst Holler, Reinhard Andreesen, Hermann Einsele
Publikováno v:
Medical Mycology. 51:818-825
Single nucleotide polymorphisms (SNPs) have been associated with an increased incidence of invasive aspergillosis (IA) after allogeneic stem cell transplantation (allo-SCT). We analyzed 41 patients with proven/probable IA after allo-SCT for an associ
Publikováno v:
Molecular Microbiology. 89:857-871
Summary Hyphae of filamentous Ascomycota consist of compartments that are connected via septal pores. To avoid a dramatic loss of cellular content after wounding, fungi developed mechanisms to occlude their septal pores. In most Pezizomycotina, so-ca
Autor:
Bernd Echtenacher, Daniela N. Männel, Anja K. Bosserhoff, Mitchell D. Knutson, Thomas Schubert, Ferdinand Hofstädter, Carole Peyssonaux
Publikováno v:
Molecular Medicine Reports. 6:838-842
On the grounds of clinical, in vitro and in vivo studies, tumour necrosis factor (TNF) is considered to be one of the inflammatory cytokines that contributes to to the generation of hypoferraemia and anaemia of inflammation (AI). We used a recently d
Autor:
Christian Taube, Matthias Klein, Markus P. Radsak, Marc Becker, Michael Stassen, Hansjörg Schild, Anastasija Michel, Tobias Bopp, Pamela Friedrich, Edgar Schmitt, Sebastian Reuter, Fatma Doener, Bernd Echtenacher
Publikováno v:
The Journal of Immunology. 186:7225-7231
Mast cell-deficient mice are a key for investigating the function of mast cells in health and disease. Allergic airway disease induced as a Th2-type immune response in mice is employed as a model to unravel the mechanisms underlying inception and pro
Autor:
Kerstin Fuchs, Manfred Kneilling, Kamran Ghoreschi, Kyu-Won Kim, Ji-Hyeon Park, Nadejda Valtcheva, Tsonwin Hai, Jürgen Brück, Martin Röcken, Anna Teske, Wolfram Hoetzenecker, Bernd Echtenacher, Konrad Hoetzenecker, Tilo Biedermann, Emmanuella Guenova, Petra Hoffmann, Florian Woelbing, Claus G. Krenn, Kyu Han Kim
Publikováno v:
Nature Medicine; Vol 18
Sepsis, sepsis-induced hyperinflammation and subsequent sepsis-associated immunosuppression (SAIS) are important causes of death. Here we show in humans that the loss of the major reactive oxygen species (ROS) scavenger, glutathione (GSH), during SAI