Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Bernd, Drewelow"'
Autor:
Andrea Klock, Ralf G. Mundkowski, Charlotte Kloft, Uwe A. Wittel, Ulrich F. Wellner, Bernd Drewelow, Sebastian G. Wicha, Ulrich T. Hopt, Tobias Keck
Publikováno v:
The Journal of Clinical Pharmacology. 59:1405-1414
Postoperative local infection is a major complication after pancreatic surgery. The aim of this prospective clinical trial was to assess the potential of moxifloxacin (MXF) to treat pancreatic infections from a pharmacokinetic (PK)/pharmacodynamic (P
Autor:
Bernd Drewelow, Jacek Szymanski, I. R. Guenther, Marietta Rottenkolber, Farker K, Werner Siegmund, Jörg Hasford, Marion Hippius, Sven Schmiedl, P. A. Thuermann
Publikováno v:
Expert opinion on drug safety. 17(2)
Background: Studies evaluating the impact of age and potentially inappropriate medication (PIM) on avoidable adverse drug reactions (ADRs) are scarce. Methods: In this prospective, multi-center, long-term (8.5 years) observational study, we analysed
Publikováno v:
Phytotherapy Research. 27:199-204
Bromelain has been used for treatment of inflammatory diseases for decades. However, the exact mechanism of action remains poorly understood. While in vitro investigations have shown conflicting effects on the release of various cytokines, no in vivo
Publikováno v:
Klinische Monatsblätter für Augenheilkunde. 229:158-161
PURPOSE The suitability of a high-hydrophilic osmotic self-inflating hydrogel expander consisting of a co-polymer of N-vinylpyrolidone and methyl methacrylate as a drug delivery system for antibiotics to prevent a postoperative infection was investig
Autor:
J. Majcher-Peszynska, G. Haase, Wolfgang Schareck, Bernd Drewelow, M. Saß, Sebastian Klammt, A. Pietsch, Ralf G. Mundkowski
Publikováno v:
European Journal of Clinical Pharmacology. 64:1093-1100
Physiological changes and local and systemic inflammation may affect plasma and tissue pharmacokinetics of antimicrobial agents in diabetics. The aim of the study was to investigate the penetration of linezolid into inflamed areas of infected diabeti
Publikováno v:
Journal of Antimicrobial Chemotherapy. 62:575-578
Objectives The aim of this study was to investigate the single- and multiple-dose pharmacokinetics (PK) of moxifloxacin and its penetration into ascitic fluid in patients with severe liver insufficiency (Child-Pugh class C). Patients and methods In a
Publikováno v:
Medicinal Chemistry Research. 17:199-204
The pharmacokinetics of piperacillin–tazobactam were investigated in another set of six patients suffering from renal failure undergoing either continuous venovenous hemofiltration (CVVH) or continuous venovenous hemodiafiltration (CVVHDF) at 1 L/h
Autor:
K. May, Sara Haack, Marion Hippius, Grit Haase, Petra A. Thürmann, Sven Schmiedl, Bernd Drewelow, Jörg Hasford, Ilselore R. Reimann, Jacek Szymanski, Marietta Rottenkolber, Werner Siegmund
Publikováno v:
Medizinische Klinik. 102:603-611
D Background: Although the value of digitalis glycosides in the treatment of heart failure is limited, approximately 255 million DDDs of digitalis glycosides (DGs) were prescribed in Germany in 2004. D Methods: The authors analyzed data from adverse
Autor:
Bernd Drewelow, Denise Katterwe, Vipul Kumar, Olaf Burkhardt, J. Majcher-Peszynska, Tobias Welte, Hartmut Derendorf
Publikováno v:
Journal of Antimicrobial Chemotherapy. 59:277-284
OBJECTIVES Most information about pharmacokinetics of antimicrobial agents is obtained from studies in healthy volunteers. However, antibiotics are therapeutically used in infected patients with very different pharmacokinetic properties compared with
Autor:
Ulrich Adam, Sven Förster, Bernd Drewelow, Ernst Klar, Rainer Wacke, Ralf G. Mundkowski, Ulrich T. Hopt
Publikováno v:
Journal of Antimicrobial Chemotherapy. 58:994-999
Objectives: Failure to prevent secondary infectious complications in acute necrotizing pancreatitis (ANP) is attributable in part to the limited penetration of antimicrobial drugs. As newer quinolones are particularly attractive owing to their antimi