Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bernat Olle"'
Autor:
Richard R Stein, Takeshi Tanoue, Rose L Szabady, Shakti K Bhattarai, Bernat Olle, Jason M Norman, Wataru Suda, Kenshiro Oshima, Masahira Hattori, Georg K Gerber, Chris Sander, Kenya Honda, Vanni Bucci
Publikováno v:
eLife, Vol 7 (2018)
Manipulation of the gut microbiota holds great promise for the treatment of diseases. However, a major challenge is the identification of therapeutically potent microbial consortia that colonize the host effectively while maximizing immunologic outco
Externí odkaz:
https://doaj.org/article/f7c2a82e817f466bb137c0d58c064ec5
Autor:
Thomas Louie, Yoav Golan, Sahil Khanna, Dmitri Bobilev, Nathalie Erpelding, Candida Fratazzi, Meg Carini, Rajita Menon, Mary Ruisi, Jason M. Norman, Jeremiah J. Faith, Bernat Olle, Minran Li, Jeffrey L. Silber, Darrell S. Pardi
Publikováno v:
JAMA. 329:1356
ImportanceThe effect of rationally defined nonpathogenic, nontoxigenic, commensal strains of Clostridia on prevention of Clostridioides difficile infection (CDI) is unknown.ObjectiveTo determine the efficacy of VE303, a defined bacterial consortium o
Autor:
Melissa Dsouza, Rajita Menon, Emily Crossette, Shakti K. Bhattarai, Jessica Schneider, Yun-Gi Kim, Shilpa Reddy, Silvia Caballero, Cintia Felix, Louis Cornacchione, Jared Hendrickson, Andrea R. Watson, Samuel S. Minot, Nick Greenfield, Lisa Schopf, Rose Szabady, Juan Patarroyo, William Smith, Pratibha Harrison, Ed J. Kuijper, Ciaran P. Kelly, Bernat Olle, Dmitri Bobilev, Jeffrey L. Silber, Vanni Bucci, Bruce Roberts, Jeremiah Faith, Jason M. Norman
Publikováno v:
Cell Host & Microbe, 30(4), 583-598.e8. CELL PRESS
Manipulation of the gut microbiota via fecal microbiota transplantation (FMT) has shown clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI). However, the variable nature of this approach makes it challenging to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d09823d48b803c9f7a60dbf0b671fc
https://hdl.handle.net/1887/3505720
https://hdl.handle.net/1887/3505720
Autor:
Kenya Honda, Koji Atarashi, Satoshi Sasajima, Zhujun Wang, Keita Nishiyama, Takahiro Matsunaga, Xiaoxi Zhang, Bernat Olle, Jason Norman, Wataru Suda, Masahira Hattori, Kazuto Watanabe, Eiichiro Watanabe, Jun Fujishiro, Shutoku Matsuyama, Makoto Ujike, Youxian Li, Yusuke Kawashima, Osamu Ohara, Sean Kearney, Damian Plichta, Ramnik Xavier, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Ho Namkoong, Yoshifumi Uwamino, Makoto Ishii, Koichi Fukunaga, Naoki Hasegawa
The gastrointestinal tract is constitutively exposed to proteases including trypsin, a serine protease originating from the pancreas1. Elevated trypsin levels in the large intestine have been implicated in pathological conditions including infectious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9118485b35bc1b6db57d3a9f14f1ad72
https://doi.org/10.21203/rs.3.rs-774361/v1
https://doi.org/10.21203/rs.3.rs-774361/v1
Autor:
Youxian Li, Eiichiro Watanabe, Yusuke Kawashima, Damian R. Plichta, Zhujun Wang, Makoto Ujike, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Keita Nishiyama, Sean M. Kearney, Wataru Suda, Masahira Hattori, Satoshi Sasajima, Takahiro Matsunaga, Xiaoxi Zhang, Kazuto Watanabe, Jun Fujishiro, Jason M. Norman, Bernat Olle, Shutoku Matsuyama, Ho Namkoong, Yoshifumi Uwamino, Makoto Ishii, Koichi Fukunaga, Naoki Hasegawa, Osamu Ohara, Ramnik J. Xavier, Koji Atarashi, Kenya Honda
Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in intestinal pathological conditions1–3. However, the players and mechanisms that underlie protease regulation in the intestinal lumen have remained uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c55bcf50b1c8790eb1861533dcb66d0
http://hdl.handle.net/10852/99193
http://hdl.handle.net/10852/99193
Autor:
Jeffrey Silber, Jason Norman, Tokuwa Kanno, Emily Crossette, Rose Szabady, Rajita Menon, Melissa Marko, Bernat Olle, Esi Lamousé-Smith
Publikováno v:
Inflammatory Bowel Diseases. 28:S65-S66
IBD patients can have reduced gut commensal abundance, relative expansion of pro-inflammatory taxa, and reduced microbial diversity and short-chain fatty acid production. FMT leads to clinical remission in some UC patients, but is a complex, nonscala
Publikováno v:
Journal of Infectious Diseases, 223, S283-S289. OXFORD UNIV PRESS INC
Treatment of bacterial infections with broad-spectrum antibiotics is a strategy severely limited by the decreased ability of the perturbed resident microbiota to control expansion of antibiotic-resistant pathogens. Live biotherapeutic products (LBPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a3e838c2cd52038f75535f1cc0bca1
https://doi.org/10.1093/infdis/jiaa779
https://doi.org/10.1093/infdis/jiaa779
Autor:
Satoru Morita, Takeshi Tanoue, Kozue Takeshita, Yutaka Kawakami, Ashwin N. Skelly, Hera Vlamakis, Jason M. Norman, Kenya Honda, Makoto Suematsu, Bernat Olle, Vanni Bucci, Tomonori Yaguchi, Takashi Inoue, Koji Atarashi, Masahira Hattori, Iori Motoo, Keiko Yasuma-Mitobe, Daniel Mucida, Seiko Narushima, Bruce L. Roberts, Dieter Riethmacher, Ramnik J. Xavier, Atsushi Shiota, Damian R. Plichta, Yuki Sugiura, Wataru Suda, Kayoko Sugita, Tsuneyasu Kaisho
Publikováno v:
Nature. 565:600-605
There is a growing appreciation for the importance of the gut microbiota as a therapeutic target in various diseases. However, there are only a handful of known commensal strains that can potentially be used to manipulate host physiological functions
Autor:
Rajita Menon, Emily M. Crossette, Shakti Bhattarai, Vanni Bucci, Jeremiah Faith, Mary Ruisi, Bernat Olle, Jeffrey L. Silber, Jason Norman
Publikováno v:
Gastroenterology. 162:S-217
Autor:
Emily M. Crossette, Rajita Menon, Esi S. Lamousé-Smith, Tokuwa Kanno, Ling-Yang Hao, Amanda Prince, Jeremiah Faith, Mary Ruisi, Bernat Olle, Jeffrey L. Silber, Jason Norman
Publikováno v:
Gastroenterology. 162:S-107