Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Bernat, Gel"'
Autor:
Edgar Creus‐Bachiller, Juana Fernández‐Rodríguez, Miriam Magallón‐Lorenz, Sara Ortega‐Bertran, Susana Navas‐Rutete, Cleofe Romagosa, Tulio M. Silva, Maria Pané, Anna Estival, Diana Perez Sidelnikova, Mireia Morell, Helena Mazuelas, Meritxell Carrió, Tereza Lausová, David Reuss, Bernat Gel, Alberto Villanueva, Eduard Serra, Conxi Lázaro
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 895-917 (2024)
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft‐tissue sarcomas with a poor survival rate, presenting either sporadically or in the context of neurofibromatosis type 1 (NF1). The histological diagnosis of MPNSTs can be challen
Externí odkaz:
https://doaj.org/article/7781165f8bd2471e855029a3e508c066
Autor:
Helena Mazuelas, Itziar Uriarte-Arrazola, Juana Fernández-Rodríguez, Miriam Magallón-Lorenz, Alberto Villanueva, Conxi Lázaro, Bernat Gel, Eduard Serra, Meritxell Carrió
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102198- (2023)
Summary: Neurofibromas are benign peripheral nervous system tumors associated with neurofibromatosis type 1, which originate from NF1(−/−) Schwann cell precursors. We describe a protocol to generate neurofibromaspheres by differentiating NF1(−/
Externí odkaz:
https://doaj.org/article/00a95e5266fc439d86b484a9ead626ee
Autor:
Miriam Magallón-Lorenz, Ernest Terribas, Sara Ortega-Bertran, Edgar Creus-Bachiller, Marco Fernández, Gerard Requena, Inma Rosas, Helena Mazuelas, Itziar Uriarte-Arrazola, Alex Negro, Tereza Lausová, Elisabeth Castellanos, Ignacio Blanco, George DeVries, Hiroyuki Kawashima, Eric Legius, Hilde Brems, Viktor Mautner, Lan Kluwe, Nancy Ratner, Margaret Wallace, Juana Fernández-Rodriguez, Conxi Lázaro, Jonathan A. Fletcher, David Reuss, Meritxell Carrió, Bernat Gel, Eduard Serra
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106096- (2023)
Summary: Malignant peripheral nerve sheath tumors (MPNSTs) are soft-tissue sarcomas of the peripheral nervous system that develop either sporadically or in the context of neurofibromatosis type 1 (NF1). MPNST diagnosis can be challenging and treatmen
Externí odkaz:
https://doaj.org/article/47d61282e05c49bc9cb540ffd4fb4a24
Autor:
Josep Biayna, Helena Mazuelas, Bernat Gel, Ernest Terribas, Gabrijela Dumbovic, Inma Rosas, Juana Fernández-Rodriguez, Ignacio Blanco, Elisabeth Castellanos, Meritxell Carrió, Conxi Lazaro, Eduard Serra
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for neurofibromin protein, a GTPase activating protein (GAP) and a negative regulator of RAS. The NF1 gene undergoes a
Externí odkaz:
https://doaj.org/article/7e2ef70d624f46fab52c22933b9b591a
Autor:
Meritxell Carrió, Helena Mazuelas, Yvonne Richaud-Patin, Bernat Gel, Ernest Terribas, Imma Rosas, Senda Jimenez-Delgado, Josep Biayna, Leen Vendredy, Ignacio Blanco, Elisabeth Castellanos, Conxi Lázaro, Ángel Raya, Eduard Serra
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 411-426 (2019)
Summary: Neurofibromatosis type 1 (NF1) is a tumor predisposition genetic disease caused by mutations in the NF1 tumor suppressor gene. Plexiform neurofibromas (PNFs) are benign Schwann cell (SC) tumors of the peripheral nerve sheath that develop thr
Externí odkaz:
https://doaj.org/article/88a77f9a7c3e4807b0539d76fcbde7b1
Autor:
Juana Fernández-Rodríguez, Andrés Morales La Madrid, Bernat Gel, Alicia Castañeda Heredia, Héctor Salvador, María Martínez-Iniesta, Catia Moutinho, Jordi Morata, Holger Heyn, Ignacio Blanco, Edgar Creus-Bachiller, Gabriel Capella, Lourdes Farré, August Vidal, Francisco Soldado, Lucas Krauel, Mariona Suñol, Eduard Serra, Alberto Villanueva, Conxi Lázaro
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: The aim of this study was to test the feasibility and utility of developing patient-derived orthotopic xenograft (PDOX) models for patients with malignant peripheral nerve sheath tumors (MPNSTs) to aid therapeutic interventions in real ti
Externí odkaz:
https://doaj.org/article/02b45471cb414606bd6321400e909f5f
Autor:
Joan Castellsagué, Bernat Gel, Juana Fernández‐Rodríguez, Roger Llatjós, Ignacio Blanco, Yolanda Benavente, Diana Pérez‐Sidelnikova, Javier García‐del Muro, Joan Maria Viñals, August Vidal, Rafael Valdés‐Mas, Ernest Terribas, Adriana López‐Doriga, Miguel Angel Pujana, Gabriel Capellá, Xose S Puente, Eduard Serra, Alberto Villanueva, Conxi Lázaro
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 608-627 (2015)
Abstract Malignant peripheral nerve sheath tumors (MPNSTs) are soft‐tissue sarcomas that can arise either sporadically or in association with neurofibromatosis type 1 (NF1). These aggressive malignancies confer poor survival, with no effective ther
Externí odkaz:
https://doaj.org/article/be1d8de904314c26af44605843b3d9f7
Autor:
Helena Mazuelas, Míriam Magallón-Lorenz, Itziar Uriarte-Arrázola, Alejandro Negro, Inma Rosas, Ignacio Blanco, Elisabeth Castellanos, Conxi Lázaro, Bernat Gel, Meritxell Carrió, Eduard Serra
Cutaneous neurofibromas (cNFs) are benign Schwann cell (SC) tumors arising from subepidermal glia. Neurofibromatosis Type 1 (NF1) individuals may develop thousands of cNFs, greatly affecting their quality of life. cNF growth is governed by the prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd7b859e8fbc86b9ea78bcf502568e0
https://doi.org/10.1101/2022.12.23.521754
https://doi.org/10.1101/2022.12.23.521754
Autor:
Núria Catasús, Miguel Torres-Martin, Alex Negro, Bernd Kuebler, Inma Rosas, Gemma Casals, Helena Mazuelas, Francesc Roca-Ribas, Emilio Amilibia, Begoña Aran, Anna Veiga, Ángel Raya, Bernat Gel, Ignacio Blanco, Eduard Serra, Meritxell Carrió, Elisabeth Castellanos
BackgroundThe appearance of bilateral vestibular schwannomas (VS) is one of the most characteristic features of NF2-related schwannomatosis (NF2-related SWN), an autosomal dominant syndrome that predisposes to the development of tumours of the nervou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95fb83bde98ce60f26ac3789a4b23af5
https://doi.org/10.1101/2022.12.14.520389
https://doi.org/10.1101/2022.12.14.520389
Autor:
Juana Fernández-Rodríguez, Bernat Gel, Conxi Lázaro, Gabrijela Dumbovic, Meritxell Carrió, Josep Biayna, Helena Mazuelas, Ernest Terribas, Ignacio Blanco, Eduard Serra, Elisabeth Castellanos, Inma Rosas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for neurofibromin protein, a GTPase activating protein (GAP) and a negative regulator of RAS. The NF1 gene undergoes alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fc2b1a7e21b5ed0eb51a8dedab0832
https://doaj.org/article/7e2ef70d624f46fab52c22933b9b591a
https://doaj.org/article/7e2ef70d624f46fab52c22933b9b591a