Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Bernardo S. Franklin"'
Autor:
Begüm Kocatürk, Youngho Lee, Nobuyuki Nosaka, Masanori Abe, Daisy Martinon, Malcolm E. Lane, Debbie Moreira, Shuang Chen, Michael C. Fishbein, Rebecca A. Porritt, Bernardo S. Franklin, Magali Noval Rivas, Moshe Arditi
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
Externí odkaz:
https://doaj.org/article/a0eb2a653cd9486ea27c4d111fb8cbc5
Autor:
Alexandre H. Lopes, Rangel L. Silva, Miriam D. Fonseca, Francisco I. Gomes, Alexandre G. Maganin, Lucas S. Ribeiro, Lucas Maciel Mauriz Marques, Fernando Q. Cunha, Jose C. Alves-Filho, Dario S. Zamboni, Norberto P. Lopes, Bernardo S. Franklin, Aurélie Gombault, Fernando Silva Ramalho, Valerie F. J. Quesniaux, Isabelle Couillin, Bernhard Ryffel, Thiago M. Cunha
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Low molecular weight carrageenan (Cg) is a seaweed-derived sulfated polysaccharide widely used as inflammatory stimulus in preclinical studies. However, the molecular mechanisms of Cg-induced inflammation are not fully elucidated.
Externí odkaz:
https://doaj.org/article/fe56c29d443545788d694f1ed8880f87
Autor:
Marina L. S. Santos, Roney S. Coimbra, Tais N. Sousa, Luiz F. F. Guimarães, Matheus S. Gomes, Laurence R. Amaral, Dhelio B. Pereira, Cor J. F. Fontes, Ibrahim Hawwari, Bernardo S. Franklin, Luzia H. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Severe thrombocytopenia can be a determinant factor in the morbidity of Plasmodium vivax, the most widespread human malaria parasite. Although immune mechanisms may drive P. vivax-induced severe thrombocytopenia (PvST), the current data on the cytoki
Externí odkaz:
https://doaj.org/article/bfbca1e9cc3f4254a142ebdfb6b55c0b
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The role of platelets has been extensively studied in the context of coagulation and vascular integrity. Their hemostatic imbalance can lead to known conditions as atherosclerotic plaques, thrombosis, and ischemia. Nevertheless, the knowledge regardi
Externí odkaz:
https://doaj.org/article/f66a865a0e944aa7b0bc6b496c0f11d0
Autor:
Ibrahim Hawwari, Nathalia Sofia Rosero Reyes, Lucas S. Ribeiro, Agnieszka Demczuk, Lino L Teichmann, Lisa Meffert, Damien Bertheloot, Bernardo S. Franklin
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
Classical CD14+monocytes are the predominant monocyte population in human blood. They are primarily engaged in host defense programs and secrete pro-inflammatory cytokines that orchestrate immune responses. While aberrant monocyte activity elicits cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a116b92a6c8a0ca7c53dfcc285b948e
https://doi.org/10.1101/2022.08.10.503291
https://doi.org/10.1101/2022.08.10.503291
Publikováno v:
Cellular and Molecular Immunology
Cellular & molecular immunology 18(5), 1106-1121 (2021). doi:10.1038/s41423-020-00630-3
Cellular & molecular immunology 18(5), 1106-1121 (2021). doi:10.1038/s41423-020-00630-3
Cell death is a fundamental physiological process in all living organisms. Its roles extend from embryonic development, organ maintenance, and aging to the coordination of immune responses and autoimmunity. In recent years, our understanding of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c87f756fcc0306f93524acdc5d91f5
https://doi.org/10.1038/s41423-020-00630-3
https://doi.org/10.1038/s41423-020-00630-3
Autor:
Damien, Bertheloot, Carlos Ws, Wanderley, Ayda H, Schneider, Lisa Dj, Schiffelers, Jennifer D, Wuerth, Jan Mp, Tödtmann, Salie, Maasewerd, Ibrahim, Hawwari, Fraser, Duthie, Cornelia, Rohland, Lucas S, Ribeiro, Lea-Marie, Jenster, Nathalia, Rosero, Yonas M, Tesfamariam, Fernando Q, Cunha, Florian I, Schmidt, Bernardo S, Franklin
Publikováno v:
EMBO molecular medicine. 14(6)
Inflammasomes sense intracellular clues of infection, damage, or metabolic imbalances. Activated inflammasome sensors polymerize the adaptor ASC into micron-sized "specks" to maximize caspase-1 activation and the maturation of IL-1 cytokines. Caspase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::518128f232aaf7d01e32e8a1d7689df8
https://pubmed.ncbi.nlm.nih.gov/35438238
https://pubmed.ncbi.nlm.nih.gov/35438238
Autor:
David F. Colon, Carlos W. Wanderley, Walter M. Turato, Vanessa F. Borges, Marcelo Franchin, Fernanda V. S. Castanheira, Daniele Nascimento, Douglas Prado, Mikhael Haruo Fernandes de Lima, Leila C Volpon, Silvia K. Kavaguti, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Bernardo S Franklin, Jose C. Alves-Filho, Fernando Q. Cunha
Sepsis survival in adults is commonly followed by immunosuppression and increased susceptibility to secondary infections. However, the long-term immune consequences of pediatric sepsis are unknown. Here, we compared the frequency of Tregs, the activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd58d397bc4e977b4ab60493a858a69
https://doi.org/10.1101/2022.01.15.476447
https://doi.org/10.1101/2022.01.15.476447
Autor:
Bernardo S. Franklin, Christine Schmitt-Mabmunyo, Marco A. Ataide, Wolfgang Kastenmüller, Gudrun Engels, Juan F. Rodriguez-Alcazar, Natalio Garbi, Eicke Latz
Publikováno v:
The journal of immunology 202(2), 550-558 (2018). doi:10.4049/jimmunol.1800107
Charcot–Leyden crystals (CLCs) are Galectin-10 protein crystals that can form after eosinophils degranulate. CLCs can appear and persist in tissues from patients with eosinophilic disorders, such as asthma, allergic reactions, and fungal and helmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ddb9d40b91187427c65411993cfeab
https://doi.org/10.4049/jimmunol.1800107
https://doi.org/10.4049/jimmunol.1800107
Autor:
Amit Sharma, Ashar Ahmad, Florian Lang, Holger Fröhlich, Karin Schuetze, Berndt Zur, Bernd Pötzsch, Bernardo S. Franklin, Johannes Oldenburg, Verena Rolfes, Jens Müller, Rosi Bissinger, Nathalia Rosero, Ullrich Wüllner
Publikováno v:
Biology 10(8), 716 (2021). doi:10.3390/biology10080716
Biology
Volume 10
Issue 8
MDPI Biology
Biology, Vol 10, Iss 716, p 716 (2021)
Biology
Volume 10
Issue 8
MDPI Biology
Biology, Vol 10, Iss 716, p 716 (2021)
Simple Summary A protein which was identified initially in nuclei and synapses of neurons and thus named alpha-synuclein (α-Syn) is significantly involved in Parkinson’s disease (PD). Mutations of the gene that codes for α-Syn cause familiar PD a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab829e5e9a243255a14b4724b93f9cc