Zobrazeno 1 - 10
of 49 669
pro vyhledávání: '"Bernardo P."'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Genomic enhancers are key transcriptional regulators which, upon the binding of sequence-specific transcription factors, activate their cognate target promoters. Although enhancers have been extensively studied in isolation, a substantial nu
Externí odkaz:
https://doaj.org/article/9ae599177a0f4ed0b0d05a7e5d06a056
Autor:
Joana M. Xavier, Ramiro Magno, Roslin Russell, Bernardo P. de Almeida, Ana Jacinta-Fernandes, André Besouro-Duarte, Mark Dunning, Shamith Samarajiwa, Martin O’Reilly, António M. Maia, Cátia L. Rocha, Nordiana Rosli, Bruce A. J. Ponder, Ana-Teresa Maia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Understanding breast cancer genetic risk relies on identifying causal variants and candidate target genes in risk loci identified by genome-wide association studies (GWAS), which remains challenging. Since most loci fall in active gene regul
Externí odkaz:
https://doaj.org/article/5911727bfc684d7781c670c96a6ca054
Autor:
Javier Mendoza-Revilla, Evan Trop, Liam Gonzalez, Maša Roller, Hugo Dalla-Torre, Bernardo P. de Almeida, Guillaume Richard, Jonathan Caton, Nicolas Lopez Carranza, Marcin Skwark, Alex Laterre, Karim Beguir, Thomas Pierrot, Marie Lopez
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Significant progress has been made in the field of plant genomics, as demonstrated by the increased use of high-throughput methodologies that enable the characterization of multiple genome-wide molecular phenotypes. These findings have provi
Externí odkaz:
https://doaj.org/article/8af619509e904512a946b50928ccabd2
Autor:
Catherine L. Jan, Algis Vingrys, Jacqueline Henwood, Xianwen Shang, Christian Davey, Peter van Wijngaarden, George Y. X. Kong, Jennifer C. Fan Gaskin, Bernardo P. Soares Bezerra, Randall S. Stafford, Mingguang He
Publikováno v:
Bioengineering, Vol 11, Iss 11, p 1139 (2024)
Background/Objectives: Glaucoma is the leading cause of irreversible blindness, with a significant proportion of cases remaining undiagnosed globally. The interpretation of optic disc and retinal nerve fibre layer images poses challenges for optometr
Externí odkaz:
https://doaj.org/article/d38b0647a2114561963705dec42bf9a2
Autor:
Zuzanna Tomkielska, Jorge Frias, Nelson Simões, Bernardo P. de Bastos, Javier Fidalgo, Ana Casas, Hugo Almeida, Duarte Toubarro
Publikováno v:
Toxins, Vol 16, Iss 11, p 491 (2024)
Physalia physalis, commonly known as the Portuguese Man o’ War, is one of the most venomous members of the Cnidaria yet is poorly understood. This article investigates the toxicity of P. physalis venom by assessing its behavioral and toxicological
Externí odkaz:
https://doaj.org/article/747995902e3f412b86e74ebf7372d121
Autor:
Bernardo P. Moreira, Sandra G. Gava, Simone Haeberlein, Sophie Gueye, Ester S. S. Santos, Michael H. W. Weber, Tigran M. Abramyan, Christoph G. Grevelding, Marina M. Mourão, Franco H. Falcone
Publikováno v:
Frontiers in Parasitology, Vol 3 (2024)
IntroductionSchistosomiasis has for many years relied on a single drug, praziquantel (PZQ) for treatment of the disease. Immense efforts have been invested in the discovery of protein kinase (PK) inhibitors; however, given that the majority of PKs ar
Externí odkaz:
https://doaj.org/article/080be4b1e91b4e59a075ffc81f851067
Publikováno v:
Energies, Vol 17, Iss 10, p 2286 (2024)
The present work aims to optimize the magnetomotive force and the end-winding leakage inductance from a discrete distribution of conductors in electrical machines through multi-objective particle swarm heuristics. From the development of an applicati
Externí odkaz:
https://doaj.org/article/0fd4c99b66d24ae99719c7acaf8b6618
Autor:
Mônica V. Andrade, Kenya Noronha, Bernardo P. C. Diniz, Gilvan Guedes, Lucas R. Carvalho, Valéria A. Silva, Júlia A. Calazans, André S. Santos, Daniel N. Silva, Marcia C. Castro
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Quantifying disease costs is critical for policymakers to set priorities, allocate resources, select control and prevention strategies, and evaluate the cost-effectiveness of interventions. Although malaria carries a very large di
Externí odkaz:
https://doaj.org/article/40f30a917a35449f8af1760b390f1403
Autor:
Bernardo P. Guimaraes, Florian Schrickel, Nils Rettberg, Shannon R. M. Pinson, Anna M. McClung, Kaushik Luthra, Griffiths G. Atungulu, Xueyan Sha, Christian de Guzman, Scott Lafontaine
Publikováno v:
Beverages, Vol 10, Iss 1, p 16 (2024)
Nineteen globally diverse rice cultivars were analyzed for various chemical parameters important to malting, including germination energy, protein, apparent amylose content, and gelatinization temperatures (GT). The rice cultivars were then malted, a
Externí odkaz:
https://doaj.org/article/6e93b700aac741dda8324cb3ae90bee9
Autor:
Lizelle Correia, Ramiro Magno, Joana M. Xavier, Bernardo P. de Almeida, Isabel Duarte, Filipa Esteves, Marinella Ghezzo, Matthew Eldridge, Chong Sun, Astrid Bosma, Lorenza Mittempergher, Ana Marreiros, Rene Bernards, Carlos Caldas, Suet-Feung Chin, Ana-Teresa Maia
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract PIK3CA mutations are the most common in breast cancer, particularly in the estrogen receptor-positive cohort, but the benefit of PI3K inhibitors has had limited success compared with approaches targeting other less common mutations. We found
Externí odkaz:
https://doaj.org/article/1f310d117fd4459e812b3168e8a100cc