Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Bernardo Morales"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-27 (2024)
Abstract In many engineering optimization problems, the number of function evaluations is severely limited by the time or cost constraints. These limitations present a significant challenge in the field of global optimization, because existing metahe
Externí odkaz:
https://doaj.org/article/d77b91220c724ea2b46b3362518602ad
Royal jelly extracellular vesicles promote wound healing by modulating underlying cellular responses
Autor:
Simón Álvarez, Pamina Contreras-Kallens, Sebastian Aguayo, Orlando Ramírez, Catalina Vallejos, Jorge Ruiz, Eva Carrasco-Gallardo, Stefanie Troncoso-Vera, Bernardo Morales, Christina M.A.P. Schuh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 541-552 (2023)
Apis mellifera royal jelly (RJ) is a well-known remedy in traditional medicine around the world and its versatile effects range from antibacterial to anti-inflammatory properties and pro-regenerative properties. As a glandular product, RJ has been sh
Externí odkaz:
https://doaj.org/article/798dd39777be48edb0b648efdb2796d1
Autor:
Barbara Cuadra, Veronica Silva, Ya-Lin Huang, Yael Diaz, Claudio Rivas, Cristobal Molina, Valeska Simon, Maria Rosa Bono, Bernardo Morales, Mario Rosemblatt, Sebastian Silva, Rodrigo Acuña, Fernando Ezquer, Marcelo Ezquer
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2073 (2024)
Acute-on-chronic liver failure (ACLF) is a syndrome marked by sudden liver function decline and multiorgan failure, predominantly acute kidney injury (AKY), in patients with chronic liver disease. Unregulated inflammation is a hallmark of ACLF; howev
Externí odkaz:
https://doaj.org/article/f8e4c0f647664b4fab61ba74bf9d2c82
Autor:
Gonzalo Ugarte, Ricardo Piña, Darwin Contreras, Felipe Godoy, David Rubio, Carlos Rozas, Marc Zeise, Rodrigo Vidal, Jorge Escobar, Bernardo Morales
Publikováno v:
Biology, Vol 12, Iss 9, p 1241 (2023)
Attention deficit-hyperactivity disorder (ADHD) is a neurodevelopmental disorder with high incidence in children and adolescents characterized by motor hyperactivity, impulsivity, and inattention. Magnetic resonance imaging (MRI) has revealed that ne
Externí odkaz:
https://doaj.org/article/5e7205bf67c1487daf5785691618f1a0
Autor:
Carolina Otero, Carolina Klagges, Bernardo Morales, Paula Sotomayor, Jorge Escobar, Juan A. Fuentes, Adrian A. Moreno, Felipe M. Llancalahuen, Ramiro Arratia-Perez, Felipe Gordillo-Fuenzalida, Michelle Herrera, Jose L. Martínez, Maité Rodríguez-Díaz
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 897 (2023)
Medicinal plants have been used since prehistoric times and continue to treat several diseases as a fundamental part of the healing process. Inflammation is a condition characterized by redness, pain, and swelling. This process is a hard response by
Externí odkaz:
https://doaj.org/article/049663a151514ed0b9eee8e9d6686ed9
Autor:
Darwin Contreras, Ricardo Piña, Claudia Carvallo, Felipe Godoy, Gonzalo Ugarte, Marc Zeise, Carlos Rozas, Bernardo Morales
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7099 (2022)
In ADHD treatment, methylphenidate (MPH) is the most frequently used medication. The present work provides evidence that MPH restored behavioral impairments and neuroplasticity due to changes in AMPAR subunit composition and distribution, as well as
Externí odkaz:
https://doaj.org/article/0a022c40e47646dbb850893667b0940b
Autor:
Muhammad Salman, Rao Zahid Abbas, Khalid Mehmood, Riaz Hussain, Sehar Shah, Mehwish Faheem, Tean Zaheer, Asghar Abbas, Bernardo Morales, Ina Aneva, José L. Martínez
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 332 (2022)
Macrocyclic lactones, particularly the avermectins, have completely revolutionized the approaches aimed at control of parasites. These avermectins are the most widely used anti-parasitic drugs in veterinary field with sales exceeding one billion US d
Externí odkaz:
https://doaj.org/article/2e0dcde7514d4ddfacb1599bb5061dfc
Autor:
Claudia Carvallo, Darwin Contreras, Gonzalo Ugarte, Ricardo Delgado, Floria Pancetti, Carlos Rozas, Ricardo Piña, Luis Constandil, Marc L. Zeise, Bernardo Morales
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Methylphenidate (MPH) is widely used in the treatment of Attention Deficit Hyperactivity Disorder. Several lines of evidence support that MPH can modulate learning and memory processes in different ways including improvement and impairment of test pe
Externí odkaz:
https://doaj.org/article/fa0c85f26cd44f03a2836c3a31a8e6f5
Autor:
Gonzalo García-Rojo, Fernando Gámiz, Estíbaliz Ampuero, Daniel Rojas-Espina, Rodrigo Sandoval, Carlos Rozas, Bernardo Morales, Ursula Wyneken, Floria Pancetti
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Acylpeptide hydrolase (APEH) is a serine hydrolase that displays two catalytic activities, acting both as an exopeptidase toward short N-acylated peptides and as an endopeptidase toward oxidized peptides or proteins. It has been demonstrated that thi
Externí odkaz:
https://doaj.org/article/23031176c3c9482f9f251506b16dfacc
Publikováno v:
Animals, Vol 9, Iss 9, p 623 (2019)
This review discusses the contribution of the use of the isolated rat aorta (IRA) as a model for the evaluation of extracts and metabolites produced by plants with a vasodilator effect in animals. This model continues to be a valuable approach for th
Externí odkaz:
https://doaj.org/article/29da960cd2bd48b6bba29d1f76e2700d