Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Bernardo J, Krause"'
Autor:
Alejandro A. Candia, Samantha C. Lean, Cindy X. W. Zhang, Daniel R. McKeating, Anna Cochrane, Edina Gulacsi, Emilio A. Herrera, Bernardo J. Krause, Amanda N. Sferruzzi-Perri
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 411 (2024)
Background: Obesity during pregnancy is related to adverse maternal and neonatal outcomes. Factors involved in these outcomes may include increased maternal insulin resistance, inflammation, oxidative stress, and nutrient mishandling. The placenta is
Externí odkaz:
https://doaj.org/article/46e485bf487a4e11b1cd4268a979ba2b
Autor:
German A. Arenas, Jose G. Valenzuela, Estefanía Peñaloza, Adolfo A. Paz, Rodrigo Iturriaga, Claudia G. Saez, Bernardo J. Krause
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1874 (2023)
PIEZO1 is a mechanosensitive cation channel implicated in shear stress-mediated endothelial-dependent vasorelaxation. Since altered shear stress patterns induce a pro-inflammatory endothelial environment, we analyzed transcriptional profiles of human
Externí odkaz:
https://doaj.org/article/f01eb53fa94d4b1d959c38046bf7eaf3
Autor:
Simon Lambden, Andrew S. Cowburn, David Macias, Tessa A. C. Garrud, Bernardo J. Krause, Dino A. Giussani, Charlotte Summers, Randall S. Johnson
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular tone and immune function, and it has been implicated in the pathophysiology of a range of cardiovascular and inflamma
Externí odkaz:
https://doaj.org/article/cf0bda5a0deb42bf96cc27c38c5aa663
Autor:
Alejandro A. Candia, Tamara Jiménez, Álvaro Navarrete, Felipe Beñaldo, Pablo Silva, Claudio García-Herrera, Amanda N. Sferruzzi-Perri, Bernardo J. Krause, Alejandro González-Candia, Emilio A. Herrera
Publikováno v:
Veterinary Sciences, Vol 10, Iss 2, p 144 (2023)
Background: Biometrical and blood flow examinations are fundamental for assessing fetoplacental development during pregnancy. Guinea pigs have been proposed as a good model to study fetal development and related gestational complications; however, lo
Externí odkaz:
https://doaj.org/article/daafaf4a18e44558be2938055120f1a9
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102675- (2021)
Summary: Whether arterial-venous differences of primary endothelial cells commonly used for vascular research are preserved in vitro remains under debate. To address this issue, a meta-analysis of Affymetrix transcriptomic data sets from human umbili
Externí odkaz:
https://doaj.org/article/1b30ec642fc84b78b3055e4835c1f5b2
Autor:
Alejandro A. Candia Henriquez, Denisse Valladares-Ide, Matías Monsalves-Álvarez, Bernardo J. Krause, Sebastián Jannas-Vela
Publikováno v:
Retos. 48:1060-1069
La actividad física y ejercicio físico durante la gestación entregan beneficios tanto para la madre, al disminuir el riesgo de desarrollar condiciones como preeclampsia y diabetes gestacional, como para el feto, disminuyendo condiciones como la ma
Autor:
Sebastian Castillo-Galán, German A. Arenas, Roberto V. Reyes, Bernardo J. Krause, Rodrigo Iturriaga
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but the pathogenic mechanisms are
Externí odkaz:
https://doaj.org/article/c86a9bd5101c4a8b8982adec2932e132
Autor:
Bernardo J. Krause, Paola Casanello, Ana C. Dias, Paulina Arias, Victoria Velarde, German A. Arenas, Marcelo D. Preite, Rodrigo Iturriaga
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Chronic intermittent hypoxia (CIH), the main attribute of obstructive sleep apnea (OSA), produces oxidative stress, endothelial dysfunction, and hypertension. Nitric oxide (NO) plays a critical role in controlling the vasomotor tone. The NO level dep
Externí odkaz:
https://doaj.org/article/69e73d3eed8e4b129df3cc69d3a171ac
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11873
Umbilical and placental vessels and endothelial cells (EC) are common models to study placental function and vascular programming. Arterio-venous differences are present in the umbilical endothelium; however, the heterogeneity of small placental vess
Autor:
Bernardo J. Krause
Publikováno v:
Journal of Cellular Physiology. 236:7984-7999
More than 30 years have passed since endothelial nitric oxide synthesis was described using the umbilical artery and vein endothelium. That seminal report set the cornerstone for unveiling the molecular aspects of endothelial function. In parallel, t