Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bernardo Abecasis"'
Autor:
Inês C. Ferreira, Estefania Torrejón, Bernardo Abecasis, Bruno M. Alexandre, Ricardo A. Gomes, Chris Verslype, Jos van Pelt, Ana Barbas, Daniel Simão, Tiago M. Bandeiras, Alessio Bortoluzzi, Sofia P. Rebelo
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100154- (2024)
Sorafenib is a multikinase inhibitor indicated for first-line treatment of unresectable hepatocellular carcinoma. Despite its widespread use in the clinic, the existing knowledge of sorafenib mode-of-action remains incomplete. To build upon the curre
Externí odkaz:
https://doaj.org/article/f74d704ab68c4276ae4077cfc067a125
Autor:
Bernardo Abecasis, Pedro G.M. Canhão, Henrique V. Almeida, Tomás Calmeiro, Elvira Fortunato, Patrícia Gomes-Alves, Margarida Serra, Paula M. Alves
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The combination of cardiomyocytes (CM) and non-myocyte cardiac populations, such as endothelial cells (EC), and mesenchymal cells (MC), has been shown to be critical for recapitulation of the human heart tissue for in vitro cell-based modeling. Howev
Externí odkaz:
https://doaj.org/article/adc0e26db7ef4bcabf0b16d6f64224c2
Autor:
Paula M. Alves, Anders Aspegren, Joana Almeida, Margarida Serra, Daniel A. M. Pais, Natalia Zapata-Linares, Felipe Prosper, Mara Domingues, Bernardo Abecasis, Inês A. Isidro, Pedro C. Vicente, Juan R. Rodriguez-Madoz
Publikováno v:
Biotechnology and Bioengineering. 118:3610-3617
Hepatocyte-like cells derived from human-induced pluripotent stem cells (hiPSC-HLC) are expected to have important applications in drug screening and regenerative medicine. However, hiPSC-HLC are difficult to produce on a large-scale to obtain releva
Autor:
S.C. Rosa, Pedro Gouveia, Bernardo Abecasis, Paula M. Alves, Lino Ferreira, Margarida Serra, Patrícia Gomes-Alves
Publikováno v:
Biotechnology and Bioengineering. 116:1245-1252
In vitro cell-based models that better mimic the human heart tissue are of utmost importance for drug development and cardiotoxicity testing but also as tools to understand mechanisms related with heart disease at cellular and molecular level. Beside
Autor:
Margarida Serra, M. J. T. Carrondo, Bernardo Abecasis, Maria J. Sebastião, Patrícia Gomes-Alves, Paula M. Alves
Publikováno v:
Bioreactors for Stem Cell Expansion and Differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6bbe16829ed1e52edc78cde86661e91
https://doi.org/10.1201/9780429453144-4
https://doi.org/10.1201/9780429453144-4
Autor:
Martina Micheletti, Andrea Ducci, Bernardo Abecasis, Jasmin J. Samaras, Maria margarida Serra
Publikováno v:
Journal of biotechnology. 287
Cardiomyocytes (CMs), derived from pluripotent stem cells (PSCs), have the potential to be used in cardiac repair. Addition of physical cues, such as electrical and mechanical stimulations, have proven to significantly effect morphology, density, car
Autor:
P. Marques Alves, Bernardo Abecasis, Sergey Yu. Luchkin, S.C. Rosa, J. B. Nunes, Henrique V. Almeida, Arianna Menciassi, Rose Cristina Veiga Gomes de Carvalho, Margarida Serra, L. Silva Ferreira, L. R. Monteiro, Leonardo Ricotti, P. Jorge Oliveira, P. José Gouveia, A. Leonidovitch Kholkin, F. Sofia Carvalho, R. Pires das Neves
Publikováno v:
Biomaterials
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The use of engineered cardiac tissue for high-throughput drug screening/toxicology assessment remains largely unexplored. Here we propose a scaffold that mimics aspects of cardiac extracellular matrix while preserving the contractility of cardiomyocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25660341e7af51a53f7bfc41e71c45a
https://hdl.handle.net/10995/73662
https://hdl.handle.net/10995/73662
Autor:
Bernardo Abecasis, Tomás Calmeiro, Paula M. Alves, Elvira Fortunato, Miguel F. Tenreiro, Henrique V. Almeida, Deolinda Santinha, Margarida Serra, Lino Ferreira, Ana F. Louro
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The work here presented was funded by Fundacao para a Ciencia e Tecnologia (FCT) projects NETDIAMOND (SAICTPAC/0047/2015), financially supported by FEEI-Lisboa2020 and FCT/POCI-01-0145-FEDER-016385, and MetaCardio (PTDC/BTM-SAL/32566/2017); iNOVA4-He
Autor:
'Bernardo Abecasis
Publikováno v:
Bernardo Abecasis