Procognitive and neurotrophic benefits of α5-GABA-A receptor positive allosteric modulation in a β-amyloid deposition mouse model of Alzheimer's disease pathology.

Autor: Bernardo AM; Campbell Family Mental Health Research Institute of CAMH, 250 college street, Toronto, ON M5T 1R8, Canada., Marcotte M; Campbell Family Mental Health Research Institute of CAMH, 250 college street, Toronto, ON M5T 1R8, Canada., Wong K; Campbell Family Mental Health Research Institute of CAMH, 250 college street, Toronto, ON M5T 1R8, Canada., Sharmin D; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, 3210 N Cramer Street, WI 53211, USA., Pandey KP; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, 3210 N Cramer Street, WI 53211, USA., Cook JM; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, 3210 N Cramer Street, WI 53211, USA., Sibille EL; Campbell Family Mental Health Research Institute of CAMH, 250 college street, Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 college street, Toronto, ON M5T 1R8, Canada; Department of Pharmacology and Toxicology, University of Toronto, Medical Sciences Building, 1 King's College Cir Room 4207, Toronto, ON M5S 1A8, Canada. Electronic address: Etienne.sibille@camh.ca., Prevot TD; Campbell Family Mental Health Research Institute of CAMH, 250 college street, Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 college street, Toronto, ON M5T 1R8, Canada; Department of Pharmacology and Toxicology, University of Toronto, Medical Sciences Building, 1 King's College Cir Room 4207, Toronto, ON M5S 1A8, Canada. Electronic address: thomas.prevot@camh.ca.

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2024 Dec 10; Vol. 147, pp. 49-59. Date of Electronic Publication: 2024 Dec 10.