Differences between the glycosylation patterns of haptoglobin isolated from skin scales and plasma of psoriatic patients.

Autor: Bernardetta Maresca, Luisa Cigliano, Maria Stefania Spagnuolo, Fabrizio Dal Piaz, Maria M Corsaro, Nicola Balato, Massimiliano Nino, Anna Balato, Fabio Ayala, Paolo Abrescia

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52040 (2012)

Improved diagnosis of psoriasis, by new biomarkers, is required for evaluating the progression rate of the disease and the response to treatment. Haptoglobin (Hpt), a glycoprotein secreted by hepatocytes and other types of cells including keratinocyt

Externí odkaz: https://doaj.org/article/d36a4384682248c5a0aafd06f222c5f3

Haptoglobin interacts with apolipoprotein E and beta-amyloid and influences their crosstalk

Autor: Tommaso Piccoli, Maria Stefania Spagnuolo, Chiara Cupidi, Luisa Cigliano, Raffaele Maletta, Albino Carrizzo, Carlo Veronesi, Valeria La Marca, Amalia C. Bruni, Bernardetta Maresca, Paolo Abrescia

Publikováno v: ACS chemical neuroscience (2014). doi:10.1021/cn500099f
info:cnr-pdr/source/autori:Spagnuolo MS, Maresca B, La Marca V, Carrizzo A, Veronesi C, Cupidi C, Piccoli T, Maletta RG, Bruni AC, Abrescia P, Cigliano L/titolo:Haptoglobin Interacts with Apolipoprotein E and Beta-Amyloid and Influences Their Crosstalk/doi:10.1021%2Fcn500099f/rivista:ACS chemical neuroscience/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume

Beta-amyloid accumulation in brain is a driving force for Alzheimer's disease pathogenesis. Apolipoprotein E (ApoE) represents a critical player in beta-amyloid homeostasis, but its role in disease progression is controversial. We previously reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e117f6be0a7343561b0507fafba0638
https://pubmed.ncbi.nlm.nih.gov/25058565

Structure and biological activity of a conformational constrained apolipoprotein A-I-derived helical peptide targeting the protein haptoglobin

Autor: Bernardetta Maresca, Luisa Cigliano, Rossella Di Stasi, Donatella Diana, Luca Domenico D'Andrea, Roberto Fattorusso, Maria Stefania Spagnuolo, Lucia De Rosa

Publikováno v: RSC advances 4 (2014): 51353–51361. doi:10.1039/c4ra08507h
info:cnr-pdr/source/autori:Cigliano, Luisa; De Rosa, Lucia; Diana, Donatella; Di Stasi, Rossella; Spagnuolo, Maria Stefania; Maresca, Bernardetta; Fattorusso, Roberto; D'Andrea, Luca D./titolo:Structure and biological activity of a conformational constrained apolipoprotein A-I-derived helical peptide targeting the protein haptoglobin/doi:10.1039%2Fc4ra08507h/rivista:RSC advances/anno:2014/pagina_da:51353/pagina_a:51361/intervallo_pagine:51353–51361/volume:4

The development of novel pharmacological treatments for atherosclerosis is an active research field in medicinal chemistry. It has been shown that the acute phase protein haptoglobin (Hpt) plays a role in modulating the reverse cholesterol transport

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d35edaea545dee4afb92a3a24fd1cdc
http://hdl.handle.net/11591/345003

Lecithin-cholesterol acyltransferase in brain: Does oxidative stress influence the 24-hydroxycholesterol esterification?

Autor: Bernardetta Maresca, Paolo Abrescia, Fabrizio Dal Piaz, Luisa Cigliano, Maria Stefania Spagnuolo, Valeria La Marca, Giuseppe Di Iorio

Publikováno v: Neuroscience research
info:cnr-pdr/source/autori:La Marca V, Maresca B, Spagnuolo MS, Cigliano L, Dal Piaz F, Di Iorio G, Abrescia P./titolo:Lecithin-cholesterol acyltransferase in brain: Does oxidative stress influence the 24-hydroxycholesterol esterification?/doi:10.1016%2Fj.neures.2015.09.008/rivista:Neuroscience research (Print)/anno:2016/pagina_da:19/pagina_a:27/intervallo_pagine:19–27/volume:105
(2015). doi:10.1016/j.neures.2015.09.008
info:cnr-pdr/source/autori:La Marca V, Maresca B, Spagnuolo MS, Cigliano L, Dal Piaz F, Di Iorio G, Abrescia P./titolo:Lecithin-cholesterol acyltransferase in brain: Does oxidative stress influence the 24-hydroxycholesterol esterification?/doi:10.1016%2Fj.neures.2015.09.008/rivista:Neuroscience research (Print)/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume

24-Hydroxycholesterol (24OH-C) is esterified by the enzyme lecithin-cholesterol acyltransferase (LCAT) in the cerebrospinal fluid (CSF). We report here that the level of 24OH-C esters was lower in CSF of patients with amyotrophic lateral sclerosis th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a7167457a01369a1f25137bc0fafa3
http://www.sciencedirect.com/science/article/pii/S0168010215002321

Understanding the role of haptoglobin in psoriasis: effects of ultraviolet B

Autor: Nicola Balato, R. Di Caprio, Martina Mattii, Serena Lembo, Maria Schiattarella, Maria Stefania Spagnuolo, Fabio Ayala, Annunziata Raimondo, Anna Balato, Paolo Abrescia, Luisa Cigliano, Bernardetta Maresca

Publikováno v: Clinical and experimental dermatology
(2015). doi:10.1111/ced.12667
info:cnr-pdr/source/autori:Maresca B.; Lembo S.; Ayala F.; Balato N.; Di Caprio R.; Mattii M.; Raimondo A.; Schiattarella M.; Abrescia P.; Spagnuolo M.S.; Cigliano L.; Balato A./titolo:Understanding the role of haptoglobin in psoriasis: Effects of ultraviolet B/doi:10.1111%2Fced.12667/rivista:Clinical and experimental dermatology (Print)/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume

Summary Background Haptoglobin (Hp) is one of the acute phase proteins, whose main function is to bind free haemoglobin (Hb) and transport it to the liver for degradation and iron recycling. In addition to its role as an Hb scavenger, Hp has been sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e610ac2053d9672962ea715751c5e442
https://pubmed.ncbi.nlm.nih.gov/25958740