Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bernard Y K Binder"'
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82134 (2013)
Ischemic diseases such as peripheral vascular disease (PVD) affect more than 15% of the general population and in severe cases result in ulcers, necrosis, and limb loss. While the therapeutic delivery of growth factors to promote angiogenesis has bee
Externí odkaz:
https://doaj.org/article/7e7bb787b9ad40d5b4ea5657af1bc635
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1184-1201 (2021)
Abstract Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D
Externí odkaz:
https://doaj.org/article/a4bd86161f9d4a74ab0467662ceef9e0
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1184-1201 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1184-1201 (2021)
Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e058574266c1a087a905d055d5b9260
https://pubmed.ncbi.nlm.nih.gov/33818906
https://pubmed.ncbi.nlm.nih.gov/33818906
Autor:
Shoujian Wang, Nader Sheibani, Michael J. Miller, David G. Belair, Bernard Y. K. Binder, Soesiawati R. Darjatmoko, William L. Murphy
Publikováno v:
Biomaterials. 93:27-37
Vascular endothelial growth factor (VEGF) spatial and temporal activity must be tightly controlled during angiogenesis to form perfusable vasculature in a healing wound. The native extracellular matrix (ECM) regulates growth factor activity locally v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a66d97ce544cb055ec5ff50ed97a46
https://doi.org/10.1016/j.biomaterials.2016.03.021
https://doi.org/10.1016/j.biomaterials.2016.03.021
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 6, Pp 773-781 (2016)
Stem Cells Translational Medicine
Stem cells translational medicine, vol 5, iss 6
Stem Cells Translational Medicine
Stem cells translational medicine, vol 5, iss 6
Mesenchymal stem cell (MSC)-based therapies are under investigation for tissue repair but suffer from poor cell persistence and engraftment upon transplantation. When entrapped in an adhesive biomaterial, MSC spheroids exhibited improved survival and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c9b3f58cd3df95be8af4a7525ffc03
https://doaj.org/article/e6f31af0effe43cb993a31c413625437
https://doaj.org/article/e6f31af0effe43cb993a31c413625437
Publikováno v:
Tissue engineering. Part B, Reviews, vol 21, iss 6
The presentation and controlled release of bioactive signals to direct cellular growth and differentiation represents a widely used strategy in tissue engineering. Historically, work in this field has primarily focused on the delivery of large cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6be898ee44c8936f679915067a28e1f
https://doi.org/10.1089/ten.teb.2015.0107
https://doi.org/10.1089/ten.teb.2015.0107
Autor:
Marissa L. Hughbanks, J. Kent Leach, Bernard Y. K. Binder, Kaitlin C. Murphy, Caroline Vissers
Publikováno v:
Annals of biomedical engineering, vol 43, iss 8
Mesenchymal stem/stromal cells (MSCs) are under examination for use in cell therapies to repair bone defects resulting from trauma or disease. MSCs secrete proangiogenic cues and can be induced to differentiate into bone-forming osteoblasts, yet ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee0cb5c701f2ff85cb770dd8241a952
https://doi.org/10.1007/s10439-014-1227-x
https://doi.org/10.1007/s10439-014-1227-x
Autor:
Shion Matsumoto, Glenn R. Gaudette, Michal Adamski, William L. Murphy, John Wirth, Hau D. Le, Gianluca Fontana, Jae Sung Lee, Joshua R. Gershlak, Bernard Y. K. Binder
Publikováno v:
Advanced Healthcare Materials. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b907ea55b50c34cab5651a387007417
https://doi.org/10.1002/adhm.201770038
https://doi.org/10.1002/adhm.201770038
Autor:
Alycia Kent, Go Urabe, Mengxue Zhang, Yichen Zhu, Yatao Shi, Xu Dong Shi, Lian-Wang Guo, William L. Murphy, K. Craig Kent, Jianjuan Ke, Bowen Wang, Drew Al. Roenneburg, Toshio Takayama, Lingjun Li, Yifan Zhou, Bernard Y. K. Binder, Daniel DiRenzo, Christopher Little, Shakti A. Goel
Publikováno v:
Scientific Reports
To date, there is no periadventitial drug delivery method available in the clinic to prevent restenotic failure of open vascular reconstructions. Resveratrol is a promising anti-restenotic natural drug but subject to low bioavailability when systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249d0d06c4a11455dc146faefa6193b5
https://doi.org/10.1038/srep41916
https://doi.org/10.1038/srep41916
Autor:
Marsha W. Rolle, Gianluca Fontana, David Dolivo, Carole L. Cramer, Tianhong Yang, Katrina J. Hansen, Sara A. Larson, Joshua R. Gershlak, Tanja Dominko, Luke R. Perreault, Glenn R. Gaudette, William L. Murphy, Fabricio Medina-Bolivar, Pamela J. Weathers, Sarah Hernandez, Bernard Y. K. Binder
Publikováno v:
Biomaterials.
Despite significant advances in the fabrication of bioengineered scaffolds for tissue engineering, delivery of nutrients in complex engineered human tissues remains a challenge. By taking advantage of the similarities in the vascular structure of pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808edbed84ba7a5b9083afbd8e5f8422