Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Bernard S. Jortner"'
Autor:
Xingdong Yang, Guohua Li, Ke Wen, Tammy Bui, Fangning Liu, Jacob Kocher, Bernard S Jortner, Marlice Vonck, Kevin Pelzer, Jie Deng, Runan Zhu, Yuyun Li, Yuan Qian, Lijuan Yuan
Publikováno v:
Emerging Microbes and Infections, Vol 3, Iss 1, Pp 1-12 (2014)
Vaccine development and pathogenesis studies for human enterovirus 71 are limited by a lack of suitable animal models. Here, we report the development of a novel neonatal gnotobiotic pig model using the non-pig-adapted neurovirulent human enterovirus
Externí odkaz:
https://doaj.org/article/983f0d9d45d54e82839649d0571d08e3
Autor:
Brad Bolon, Kevin D. Woolard, Lisa G. Lanigan, Bernard S Jortner, Duncan S. Russell, Virginia Godfrey, Ingrid D. Pardo, Mark T. Butt
Publikováno v:
Veterinary Pathology. 58:10-33
The peripheral nervous system (PNS) relays messages between the central nervous system (brain and spinal cord) and the body. Despite this critical role and widespread distribution, the PNS is often overlooked when investigating disease in diagnostic
Autor:
Gary S. Johnson, Sandra Hancock, Garrett Bullock, Scott V. Dindot, Brian F. Porter, Ryan N. Doan, Derick B. Whitley, Jonathan M. Levine, Bernard S. Jortner, Andy Ambrus, Samantha C. St. Jean
Publikováno v:
Veterinary pathology. 59(1)
Canine multiple system degeneration (CMSD) is a progressive hereditary neurodegenerative disorder commonly characterized by neuronal degeneration and loss in the cerebellum, olivary nuclei, substantia nigra, and caudate nuclei. In this article, we de
Autor:
Xiaofeng Liao, Jingjing Ren, Cheng-Hsin Wei, A Catharine Ross, Thomas E Cecere, Bernard S Jortner, S Ansar Ahmed, Xin M Luo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118176 (2015)
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood. Here we demonstrate that tRA
Externí odkaz:
https://doaj.org/article/ba77d0cca0be4babb980e289c9891b11
Autor:
Georg Krinke, Brad Bolon, Bernard S Jortner, Deepa B. Rao, Karl F. Jensen, Robert H. Garman, Mark T. Butt, Lydia L. Andrews-Jones, Michael S. Thibodeau, Ingrid D. Pardo, James P. Morrison, Alok K. Sharma
Publikováno v:
Toxicologic Pathology. 46:372-402
Peripheral nervous system (PNS) toxicity is surveyed inconsistently in nonclinical general toxicity studies. These Society of Toxicologic Pathology “best practice” recommendations are designed to ensure consistent, efficient, and effective sampli
Autor:
Bernard S. Jortner
Publikováno v:
Toxicologic pathology. 48(1)
There is a striking difference in the potential for regeneration of injured axons in the central and peripheral nervous systems, which is important in neurotoxicologic studies. In contrast to the former, there is a ready mechanism for replacement of
Autor:
Bernard S Jortner
Publikováno v:
Toxicologic pathology. 48(1)
This review illustrates common lesions of peripheral nerve myelinated fibers that occur in toxic neuropathy. These distinctive structural changes help to define the site of toxicant activity and thus predict the course of neurotoxic disease and recov
Autor:
William M. Valentine, Brad Bolon, Ingrid D. Pardo, Bernard S. Jortner, Mark T. Butt, Alok K. Sharma, Deepa B. Rao, Joseph C. Arezzo
Publikováno v:
Toxicologic pathology. 46(8)
Peripheral nervous system (PNS) toxicity is a frequent adverse effect encountered in patients treated with certain therapeutics (e.g., antiretroviral drugs, cancer chemotherapeutics), in occupational workers exposed to industrial chemicals (e.g., sol
Autor:
Bernard S. Jortner, Rachel B Matusow, Ian P. Herring, Jennifer Dreyfus, John H. Rossmeisl, Kurt L. Zimmerman, Pablo Piñeyro, Orr Rozov
Publikováno v:
Clinical Case Reports
Intraocular neoplasms in dogs are uncommon in comparison with other anatomic locations [1–4]. Over 75% of these cases are attributed to melanocytic neoplasia [1]. A majority of the remaining cases (~22%) are comprised of lymphoma, metastatic neopla
Autor:
Pablo Piñeyro, D. Philip Sponenberg, Theresa E. Pancotto, Rosalind H. M. King, Bernard S. Jortner
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 27:762-766
Chronic inflammatory demyelinating polyradiculoneuropathy occurred in an 11-year-old Labrador Retriever dog. Spinal cord compression resulted from massive radiculitis with prominent cholesterol granulomas. Cholesterol deposition and associated granul