Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Bernard Séguin"'
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2346 (2023)
Human rhabdomyosarcomas are rarely cured by surgical resection alone. This is also true for high-grade soft tissue sarcomas in dogs. Dogs with spontaneous sarcoma are good models for clinical responses to new cancer therapies. Strategic combinations
Externí odkaz:
https://doaj.org/article/c755e898e10b48bc94ea779f2da7a1f9
Autor:
Cyril Parachini‐Winter, Kaitlin M. Curran, MacKenzie Pellin, Travis Laver, Camille Hanot, Timothy H. Vernier, Bernard Séguin
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 5, Pp 2200-2208 (2019)
Abstract Background Metastasis of appendicular osteosarcoma is most common to the lungs and is generally considered a terminal event in dogs. Behavior and prognosis associated with cutaneous or subcutaneous metastases (CSM) is poorly defined. Objecti
Externí odkaz:
https://doaj.org/article/5e4736915bf141dfb7d3390ca644f121
Autor:
Qi Wei, Stephen A. Ramsey, Maureen K. Larson, Noah E. Berlow, Donasian Ochola, Christopher Shiprack, Amita Kashyap, Bernard Séguin, Charles Keller, Christiane V. Löhr
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-18 (2019)
Abstract Background Feline injection-site sarcoma (FISS), an aggressive iatrogenic subcutaneous malignancy, is challenging to manage clinically and little is known about the molecular basis of its pathogenesis. Tumor transcriptome profiling has prove
Externí odkaz:
https://doaj.org/article/4e3748806409438a85f88ef51630cd0b
Autor:
Bernard Séguin
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Soft tissue sarcomas (STSs) remain a therapeutic challenge for pediatric and adolescent and young adult (AYA) patients. Still today, surgery, radiation therapy, and chemotherapy remain the mainstay of treatment. Obstacles in developing new treatment
Externí odkaz:
https://doaj.org/article/d939b6624d2d401e8a005ac52dd3a83f
Publikováno v:
Viruses, Vol 10, Iss 8, p 398 (2018)
Many oncolytic viruses that are efficacious in murine cancer models are ineffective in humans. The outcomes of oncolytic virus treatment in dogs with spontaneous tumors may better predict human cancer response and improve treatment options for dogs w
Externí odkaz:
https://doaj.org/article/b91d5c751d814a63b0163610faf1d958
Autor:
Lydia Youmans, Cynthia Taylor, Edwin Shin, Adrienne Harrell, Angela E Ellis, Bernard Séguin, Xinglai Ji, Shaying Zhao
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50813 (2012)
Sporadic canine colorectal cancers (CRCs) should make excellent models for studying the corresponding human cancers. To molecularly characterize canine CRC, we investigated exonic sequence mutations of adenomatous polyposis coli (APC), the best known
Externí odkaz:
https://doaj.org/article/9e8e0427b68140379ce24d153d3e6391
Autor:
Marie Llido, Linh-Aurore Le Bras, Vladimir Brailovski, Bernard Séguin, Isabelle Masseau, Yvan Petit, Bertrand Lussier
Publikováno v:
American Journal of Veterinary Research. :1-8
OBJECTIVE Osteosarcoma frequently affects the proximal humerus in dogs. In veterinary medicine, no therapeutic option for the treatment of osteosarcoma satisfactorily preserves limb function. 3D-printed personalized endoprosthesis offers a promising
Publikováno v:
Veterinary and Comparative Oncology. 21:131-137
Autor:
Bernard Séguin, Lisa Brownlee
Publikováno v:
Veterinary Surgical Oncology. :569-623
Autor:
Margaret A. Nagai-Singer, Suzanne M. Royer, Brittney Byer, Daniel P. Regan, Charles Keller, Bernard Séguin, Joanne L. Tuohy
Publikováno v:
Vet Pathol
Canine rhabdomyosarcoma (RMS) presents a diagnostic challenge due to its overlapping histologic features with other soft tissue sarcomas. The diagnosis of RMS currently relies on positive immunohistochemical (IHC) labeling for desmin; however, desmin