Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress.

Autor: Qin P; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA pu.2.qin@gsk.com., Arabacilar P; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Bernard RE; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Bao W; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Olzinski AR; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Guo Y; Basic & Translational Research, School of Medicine, Vanderbilt University, Nashville, TN., Lal H; Basic & Translational Research, School of Medicine, Vanderbilt University, Nashville, TN., Eisennagel SH; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Platchek MC; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Xie W; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Del Rosario J; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Nayal M; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Lu Q; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Roethke T; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Schnackenberg CG; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Wright F; Preclinical and Translational Imaging, Platform Technology and Science, GlaxoSmithKline, King of Prussia, PA., Quaile MP; Preclinical and Translational Imaging, Platform Technology and Science, GlaxoSmithKline, King of Prussia, PA., Halsey WS; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Hughes AM; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Sathe GM; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Livi GP; Target and Pathway Validation, Target Sciences, GlaxoSmithKline, King of Prussia, PA., Kirkpatrick RB; Pipeline Future's Group, GlaxoSmithKline, King of Prussia, PA., Qu XA; Computational Biology, Projects Clinical Platforms and Sciences, GlaxoSmithKline, King of Prussia, PA., Rajpal DK; Computational Biology, Projects Clinical Platforms and Sciences, GlaxoSmithKline, King of Prussia, PA., Faelth Savitski M; Cellzome GmbH, A GSK Company, GlaxoSmithKline, King of Prussia, PA., Bantscheff M; Cellzome GmbH, A GSK Company, GlaxoSmithKline, King of Prussia, PA., Joberty G; Cellzome GmbH, A GSK Company, GlaxoSmithKline, King of Prussia, PA., Bergamini G; Cellzome GmbH, A GSK Company, GlaxoSmithKline, King of Prussia, PA., Force TL; Basic & Translational Research, School of Medicine, Vanderbilt University, Nashville, TN., Gatto GJ Jr; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Hu E; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA., Willette RN; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area GlaxoSmithKline, King of Prussia, PA.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2017 May 09; Vol. 6 (5). Date of Electronic Publication: 2017 May 09.

50 YEARS OF PMEL TSUNAMI RESEARCH AND DEVELOPMENT.

Autor: Bernard, Eddie¹ eddie.bernard@comcast.net, Meinig, Christian², Titov, Vasily V.³, Yong Wei⁴

Publikováno v: Oceanography. Oct2023, Vol. 36 Issue 2/3, p175-185. 11p.

Rectifying METTL4-Mediated N6-Methyladenine Excess in Mitochondrial DNA Alleviates Heart Failure.

Autor: Fuyang Zhang, Ling Zhang, Guangyu Hu, Xiyao Chen, Hui Liu, Congye Li, Xiong Guo, Chong Huang, Fangfang Sun, Tongzheng Li, Zhe Cui, Yongzhen Guo, Wenjun Yan, Yunlong Xia, Zhiyuan Liu, Zhen Lin, Weixun Duan, Linhe Lu, Xinyi Wang, Zhengyang Wang

Publikováno v: Circulation; 10/29/2024, Vol. 150 Issue 18, p1441-1458, 18p

The manifold costs of being a non-native English speaker in science.

Autor: Amano, Tatsuya^1,2 (AUTHOR) t.amano@uq.edu.au, Ramírez-Castañeda, Valeria^3,4 (AUTHOR), Berdejo-Espinola, Violeta^1,2 (AUTHOR), Borokini, Israel⁵ (AUTHOR), Chowdhury, Shawan^1,2,6,7,8 (AUTHOR), Golivets, Marina⁹ (AUTHOR), González-Trujillo, Juan David¹⁰ (AUTHOR), Montaño-Centellas, Flavia^11,12 (AUTHOR), Paudel, Kumar¹³ (AUTHOR), White, Rachel Louise¹⁴ (AUTHOR), Veríssimo, Diogo¹⁵ (AUTHOR)

Publikováno v: PLoS Biology. 7/18/2023, Vol. 21 Issue 7, p1-27. 27p. 1 Diagram, 1 Chart, 4 Graphs.

Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment.

Autor: Olzinski AR; Cardiovascular and Urogenital Center of Excellence in Drug Discovery, King of Prussia, PA, USA., Turner GH, Bernard RE, Karr H, Cornejo CA, Aravindhan K, Hoang B, Ringenberg MA, Qin P, Goodman KB, Willette RN, Macphee CH, Jucker BM, Sehon CA, Gough PJ

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2010 Feb; Vol. 30 (2), pp. 253-9. Date of Electronic Publication: 2009 Dec 03.