Synthesis of trifluoromethylated 1,5-benzoheteroazepines

Autor: Thierry Billard, Bernard R. Langlois, Carole Christophe

Publikováno v: Journal of Fluorine Chemistry. 155:118-123

Because of the great interest of benzoheteroazepines and trifluoromethylated compounds in medicinal chemistry, a simple strategy to synthesize trifluoromethylated 1,5-benzoheteroazepines have been described. Starting from β-trifluoromethylated enone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::922e2e4b9855fdf27ddd2d50764a0d0c
https://doi.org/10.1016/j.jfluchem.2013.06.016

A New and Direct Trifluoromethoxylation of Aliphatic Substrates with 2,4-Dinitro(trifluoromethoxy)benzene

Autor: Jean-Pierre Vors, Olivier Marrec, Bernard R. Langlois, Sergii Pazenok, Thierry Billard

Publikováno v: Advanced Synthesis & Catalysis. 352:2831-2837

The reaction of tetrabutylammonium triphenyldifluorosilicate with 2,4-dinitro(trifluoromethoxy)benzene, in acetonitrile and under microwave irradiation, generates a trifluoromethoxide anion which is able to substitute activated bromides (benzyl bromi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9eda743edeb1f06e036cfaea91437c38
https://doi.org/10.1002/adsc.201000488

2,2′-Bipyridine-3,3′-dicarboxylic carbohydrate esters and amides. Synthesis and preliminary evaluation as ligands in Cu(II)-catalysed enantioselective electrophilic fluorination

Autor: Diane M. Coe, Bernard R. Langlois, Yves Queneau, Stéphane Chambert, Aurélie Assalit, Thierry Billard

Publikováno v: Tetrahedron: Asymmetry
Tetrahedron: Asymmetry, Elsevier, 2009, 20 (5), pp.593-601. ⟨10.1016/j.tetasy.2009.02.050⟩

International audience; A series of 10 new carbohydrate-substituted bipyridines were prepared from 2,2′-bipyridine-3,3′-dicarboxylic acid, itself easily available from ortho-phenanthroline. As a preliminary exploration of their use as chiral liga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f293a82ba93d7488708f63a8f5e372c
https://doi.org/10.1016/j.tetasy.2009.02.050

(Re)investigation of the reactivity of uranium hexafluoride toward several organic functions at room temperature

Autor: Jean-Paul Alric, Thierry Billard, Bertrand Morel, Olivier Roy, Bernard Marquet, Alex Jourdan, Bernard R. Langlois

Publikováno v: Journal of Fluorine Chemistry
Journal of Fluorine Chemistry, 2014, 167, pp.74-78
Journal of Fluorine Chemistry, Elsevier, 2014, 167, pp.74-78

International audience; The annual worldwide production of UF6 is very large and this compound is not used. Consequently, it could be interesting to find some applications as organic reagent. UF6 could be considered as an oxidizer of various function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4740808a4ab420872052d5f474c100b
https://hal.science/hal-01154481

ChemInform Abstract: Synthesis of Trifluoromethylated 1,5-Benzoheteroazepines

Autor: Thierry Billard, Carole Christophe, Bernard R. Langlois

Publikováno v: ChemInform. 45

Because of the great interest of benzoheteroazepines and trifluoromethylated compounds in medicinal chemistry, a simple strategy to synthesize trifluoromethylated 1,5-benzoheteroazepines have been described. Starting from β-trifluoromethylated enone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a9ecaaab0d27922fcdd421c4b4c8992
https://doi.org/10.1002/chin.201407206