Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bernard Piqueras"'
Publikováno v:
BioTechniques, Vol 20, Iss 4, Pp 634-640 (1996)
Apoptosis induced in different cell lines can be detected and quantified in one step. Direct labeling of apoptotic cells (DLAC) was performed by incorporation of fluorescein-dUTP (F-dUTP) in DNA strand breaks by terminal deoxynucleotidyl transferase
Externí odkaz:
https://doaj.org/article/a115ba51dda74e93a664bab90620b1e2
Autor:
Damien Chaussabel, Chun I. Yu, Mark A. Michnevitz, A. Karolina Palucka, John E. Connolly, Heidi Freitas, Bernard Piqueras, Jacques Banchereau, Marc Pypaert, Casey Glaser, Sasha Tindle, Toshimichi Matsui
Publikováno v:
The Journal of Immunology. 182:6815-6823
Plasmacytoid dendritic cells (pDCs) are key regulators of antiviral immunity. They rapidly secrete IFN-α and cross-present viral Ags, thereby launching adaptive immunity. In this study, we show that activated human pDCs inhibit replication of cancer
Publikováno v:
Blood. 107:2613-2618
Host response to viral infection involves distinct effectors of innate and adaptive immunity, whose mobilization needs to be coordinated to ensure protection. Here we show that influenza virus triggers, in human blood dendritic-cell (DC) subsets (ie,
Autor:
Christian Schmitt, Bernard Piqueras, Eric Oksenhendler, Lionel Galicier, Luc Mouthon, C. Lavenu-Bombled, S. Chevret, Patrice Debré, F.Bergeron-Van Der Cruyssen
Publikováno v:
Journal of Clinical Immunology. 23:385-400
Common variable immunodeficiency (CVID) is a very heterogeneous syndrome defined by impaired immunoglobulin production. The functional classification of CVID patients on the basis of in vitro immunoglobulin production is time consuming and has never
Autor:
Wolf H. Fridman, Sophie Lebel-Binay, Franck Zinzindohoué, Nicolas Thiounn, Anne Berger, Paul H. Cugnenc, Océane Carriere, Bernard Piqueras, Claire Danel, Franck Pagès
Publikováno v:
Immunology Letters. 75:9-14
Interleukin-18 (IL-18) plays a central role in the immune response by acting on Th1 cell differentiation, cell-mediated cytotoxicity and inflammation. The role of IL-18 in cancers and inflammatory diseases is discussed in the light of our investigati
Publikováno v:
Journal of Immunological Methods. 241:147-158
To date, there is no direct way to determine the antigenic specificity of T-cells. While B-cell epitopes can be selected from phage-displayed libraries of peptides, the corresponding molecular tool for identifying T-cell epitopes does not yet exist.
Autor:
Berthold Henglein, Anne Berger, Franck Pages, Franck Zinzindohoué, Bernard Piqueras, Paul H. Cugnenc, Wolf H. Fridman, Nicolas Thiounn, Claire Danel
Publikováno v:
International Journal of Cancer. 84:326-330
The production in colon cancer of interferon-gamma (IFN-gamma), a type-1 T-helper (TH1) cytokine, is considered as a marker of good prognosis. We asked whether interleukin-18 (IL-18), which strongly induces IFN-gamma and regulates Fas ligand (Fas-L)-
Autor:
Windy Allman, Wendy K. Chung, Casey Glaser, Knut M. Wittkowski, Damien Chaussabel, Bernard Piqueras, A. Karolina Palucka, Asuncion Mejias, Octavio Ramilo, Jacques Banchereau, Monica Ardura
Publikováno v:
Blood. 109(5)
Each infectious agent represents a unique combination of pathogen-associated molecular patterns that interact with specific pattern-recognition receptors expressed on immune cells. Therefore, we surmised that the blood immune cells of individuals wit
Autor:
John E. Connolly, Bernard Piqueras, A. Karolina Palucka, Peter Dubsky, Jacques Banchereau, Hideki Ueno
Publikováno v:
Journal of clinical immunology. 25(6)
Protective immunity results from the interplay of antigen (Ag)-nonspecific innate immunity and Ag-specific adaptive immunity. The cells and molecules of the innate system employ non-clonal recognition pathways such as lectins and TLRs. B and T lympho
Autor:
Luc, Mouthon, Pascal, Godmer, Bernard, Piqueras, Pascal, Cohen, Olivier, Lortholary, Hélène, Hofmann-Radvanyi, Loïc, Guillevin
Publikováno v:
Annales de medecine interne. 153(8)
Myotonic dystrophy is an autosomal dominant muscle disorder characterized by muscle wasting and weakness and a number of other systemic abnormalities. Some patients have hypo-IgG that is asymptomatic in most of them. We report the case of a 42-year-o