Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Bernard Labedan"'
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-20 (2019)
Abstract Background In systems biology, there is an acute need for integrative approaches in heterogeneous network mining in order to exploit the continuous flux of genomic data. Simultaneous analysis of the metabolic pathways and genomic context of
Externí odkaz:
https://doaj.org/article/63556fd6ff5b4a0b8cf9e2bc0d3cac91
Publikováno v:
Journal of Molecular Evolution. 77:70-80
Dihydroorotases are universal proteins catalyzing the third step of pyrimidine biosynthesis. These zinc metalloenzymes belong to the superfamily of cyclic amidohydrolases, comprising also other enzymes that are involved in degradation of either purin
Publikováno v:
ISMB
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2008, 24 (13), pp.i322-9. ⟨10.1093/bioinformatics/btn159⟩
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2008, 24 (13), pp.i322-9. ⟨10.1093/bioinformatics/btn159⟩
Motivation: We have to cope with both a deluge of new genome sequences and a huge amount of data produced by high-throughput approaches used to exploit these genomic features. Crossing and comparing such heterogeneous and disparate data will help imp
Autor:
Stéphane Descorps-Declère, Olivier Lespinet, Bernard Labedan, Quentin Sculo, Frédéric Lemoine
Publikováno v:
Biochimie
Biochimie, Elsevier, 2007, epub ahead of print. ⟨10.1016/j.biochi.2007.09.010⟩
Biochimie, Elsevier, 2007, epub ahead of print. ⟨10.1016/j.biochi.2007.09.010⟩
The incredible development of comparative genomics during the last decade has required a correct use of the concept of homology that was previously utilized only by evolutionary biologists. Unhappily, this concept has been often misunderstood and thu
Autor:
Bernard Labedan, Olivier Lespinet
Publikováno v:
Drug discovery today.
Drug discovery today., 2006, 11, pp.300-5
Drug discovery today., 2006, 11, pp.300-5
Despite the immense progress of genomics, and the current availability of several hundreds of thousands of amino acid sequences, >39% of well-defined enzyme activities (as represented by enzyme commission, EC, numbers) are not associated with any seq
Publikováno v:
Microbiology. 150:3908-3911
Autor:
Ariel Blocker, Mark S Peppler, Philippe Normand, Sylvain Brisse, Eric D Spitzer, Kenneth L Rosenthal, David Sibley, Bernard Labedan, Patrick Forterre, Eric D Brown, Scott Gold, Mariola Garcia-Pedrajas, Shilpa Iyer, Xiaorong Lin, Lee Kroos
Publikováno v:
Current Opinion in Microbiology. 5:533-542
Autor:
Mark S Peppler, Philippe Normand, Sylvain Brisse, Eric D Spitzer, Kenneth L Rosenthal, David Sibley, Bernard Labedan, Patrick Forterre, Eric D Brown, Scott Gold, Mariola Garcia-Pedrajas, Gretel Guest, Timothy Poore, Shilpa Iyer, Lee Kroos
Publikováno v:
Current Opinion in Microbiology. 5:343-351
Publikováno v:
Comparative and Functional Genomics
Comparative and Functional Genomics, Vol 3, Iss 6, Pp 488-493 (2002)
Comparative and Functional Genomics, Vol 3, Iss 6, Pp 488-493 (2002)
Pertinent evolutionary studies are based on a correct use of homology terms such as paralogues, metalogues and orthologues. Such crucial concepts have been applied to intragenomic and intergenomic analyses. A further requisite is a proper definition
Autor:
Ariel Blocker, Mark S Peppler, Philippe Normand, Francine Grimont, Eric D Spitzer, Kenneth L Rosenthal, David Sibley, Bernard Labedan, Patrick Forterre, Scott Gold, Andrea Feucht, Jeff Errington
Publikováno v:
Current Opinion in Microbiology. 4:223-232