Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Bernard L. Trumpower"'
Publikováno v:
BioTechniques, Vol 22, Iss 2, Pp 250-254 (1997)
Externí odkaz:
https://doaj.org/article/d4ced93e439d476988dc826297b33d5a
Autor:
Michael T. O’Neil, Bernard L. Trumpower, Jacob D. Johnson, Louise M. Hughes, Gordon W. Gribble, Charlotte A. Lanteri
Publikováno v:
Molecular and Biochemical Parasitology. 177:12-19
Atovaquone is a hydroxy-naphthoquinone that is used to treat parasitic and fungal infections including Plasmodium falciparum (malaria), Pneumocystis jivorecii (pneumonia) and Toxoplasma gondii (toxoplasmosis). It blocks mitochondrial oxidation of ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25d814d5b159ae7ae9279d52198fa64
https://doi.org/10.1016/j.molbiopara.2011.01.002
https://doi.org/10.1016/j.molbiopara.2011.01.002
Autor:
Bernard L. Trumpower, Michela Castellani, Oliver Anderka, Bernd Ludwig, Thomas Kleinschroth, Raul Covian
Publikováno v:
Journal of Biological Chemistry. 285:502-510
We previously proposed that the dimeric cytochrome bc1 complex exhibits half-of-the-sites reactivity for ubiquinol oxidation and rapid electron transfer between bc1 monomers (Covian, R., Kleinschroth, T., Ludwig, B., and Trumpower, B. L. (2007) J. Bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22eb1d8aeb858065f2d6ed8691577e5b
https://doi.org/10.1074/jbc.m109.072959
https://doi.org/10.1074/jbc.m109.072959
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(1):38-43
Atovaquone is a substituted 2-hydroxy-naphthoquinone used therapeutically against Plasmodium falciparum (malaria) and Pneumocystis pathogens. It acts by inhibiting the cytochrome bc1 complex via interactions with the Rieske iron–sulfur protein and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02082759272df3698820974ad99ba9d3
Autor:
Bernard L. Trumpower, Raul Covian
Publikováno v:
Journal of Biological Chemistry. 284:14359-14367
Quinol oxidation at center P of the cytochrome bc1 complex involves bifurcated electron transfer to the Rieske iron-sulfur protein and cytochrome b. It is unknown whether both electrons are transferred from the same domain close to the Rieske protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a8a1bae610f7f8522d3915665da1f3
https://doi.org/10.1074/jbc.m109.000596
https://doi.org/10.1074/jbc.m109.000596
Publikováno v:
Journal of Biological Chemistry. 284:8478-8485
The mitochondrial cytochrome bc1 complex is an essential respiratory enzyme in oxygen-utilizing eukaryotic cells. Its core subunit, cytochrome b, contains two sites, center P and center N, that participate in the electron transfer activity of the bc1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ede67c835033aa7db9c72dbae5e936
https://doi.org/10.1074/jbc.m809278200
https://doi.org/10.1074/jbc.m809278200
Publikováno v:
FEBS Journal. 276:1900-1914
The assembly status of the cytochrome bc(1) complex has been analyzed in distinct yeast deletion strains in which genes for one or more of the bc(1) subunits were deleted. In all the yeast strains tested, a bc(1) sub-complex of approximately 500 kDa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9f7ab7b978e5983f383a56fb6a09e5
https://doi.org/10.1111/j.1742-4658.2009.06916.x
https://doi.org/10.1111/j.1742-4658.2009.06916.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793:89-96
The mitochondrial respiratory chain is composed of four different protein complexes that cooperate in electron transfer and proton pumping across the inner mitochondrial membrane. The cytochrome bc1 complex, or complex III, is a component of the mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17135773adc10e5345413e4a963c35d4
https://doi.org/10.1016/j.bbamcr.2008.04.011
https://doi.org/10.1016/j.bbamcr.2008.04.011
Publikováno v:
Trends in Parasitology. 23:494-501
Atovaquone is a substituted hydroxynaphthoquinone that is used therapeutically for treating Plasmodium falciparum malaria, Pneumocystis jirovecii pneumonia and Toxoplasma gondii toxoplasmosis. It is thought to act on these organisms by inhibiting par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc006e567d84aa4037093a72abcb67e1
https://doi.org/10.1016/j.pt.2007.08.004
https://doi.org/10.1016/j.pt.2007.08.004
Publikováno v:
FEBS Journal. 274:4526-4539
We have examined the status of the cytochrome bc(1) complex in mitochondrial membranes from yeast mutants in which genes for one or more of the cytochrome bc(1) complex subunits were deleted. When membranes from wild-type yeast were resolved by nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4908d7f984b5bdac225425ca9bbad1bd
https://doi.org/10.1111/j.1742-4658.2007.05982.x
https://doi.org/10.1111/j.1742-4658.2007.05982.x