Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Bernard Kwabi-Addo"'
Autor:
Chad J. Creighton, Flora Zhang, Yiqun Zhang, Patricia Castro, Rong Hu, Md Islam, Somiranjan Ghosh, Michael Ittmann, Bernard Kwabi-Addo
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
African American (AA) men have the highest incidence and mortality rate from Prostate cancer (PCa) than any other racial/ethnic group. To date, PCa genomic studies have largely under-represented tumour samples from AA men. We measured genome-wide DNA
Externí odkaz:
https://doaj.org/article/23d25d808dcd449d914fff78cc1dda88
Autor:
Mohammad Khan, Kaitlyn Hearn, Christian Parry, Mudasir Rashid, Hassan Brim, Hassan Ashktorab, Bernard Kwabi-Addo
Publikováno v:
Nutrients, Vol 16, Iss 1, p 114 (2023)
Prostate cancer is the most common cancer and the second leading cause of cancer deaths among men in the USA. Several studies have demonstrated the antitumor properties of saffron in different types of cancers, including prostate cancer. The oral adm
Externí odkaz:
https://doaj.org/article/21b88173a47842a19f55f72a807cde5b
Autor:
Tanmoy Mondal, Coleman I. Smith, Christopher A. Loffredo, Ruth Quartey, Gemeyel Moses, Charles D. Howell, Brent Korba, Bernard Kwabi-Addo, Gail Nunlee-Bland, Leanna R. Rucker, Jheannelle Johnson, Somiranjan Ghosh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16654 (2023)
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is becoming the most common chronic liver disease worldwide and is of concern among African Americans (AA) in the United States. This pilot study evaluated the differential gene express
Externí odkaz:
https://doaj.org/article/40678cd754d046c79325b9e9e8dfb276
Autor:
Julius S. Ngwa, Evaristus Nwulia, Oyonumo Ntekim, Fikru B. Bedada, Bernard Kwabi-Addo, Sheeba Nadarajah, Steven Johnson, William M. Southerland, John Kwagyan, Thomas O. Obisesan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2022)
BackgroundDNA methylation at CpG sites is a vital epigenetic modification of the human genome affecting gene expression, and potentially, health outcomes. However, evidence is just budding on the effects of aerobic exercise-induced adaptation on DNA
Externí odkaz:
https://doaj.org/article/b126d8ea0b84418ca93fa8ca2d442de7
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273717 (2022)
BackgroundLow socioeconomic status neighborhood exposure to stress and violence may be sources of negative stimuli that poses significant health risks for children, adolescents and throughout the life course of an individual. The study aims to invest
Externí odkaz:
https://doaj.org/article/3f8ba02966944b0f888a0e18e813ed38
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 14, Iss , Pp 100247- (2021)
Exposure to violence (ETV) has been linked to epigenomics mechanisms such as DNA methylation (DNAm). We used epigenetic profiling of blood collected from 32 African American young adult males who lived in Washington DC to determine if changes in DNAm
Externí odkaz:
https://doaj.org/article/14a4638da76b4773bb934c86bc4629f1
Autor:
Emmanuel Moses-Fynn, Wei Tang, Desta Beyene, Victor Apprey, Robert Copeland, Yasmine Kanaan, Bernard Kwabi-Addo
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203322 (2018)
The objective of this work was to investigate the clinical significance of promoter gene DNA methylation changes in whole blood from African-American (AA) men with prostate cancer (PCa). We used high throughput pyrosequencing analysis to quantify per
Externí odkaz:
https://doaj.org/article/73a34edc5ef443559dbb653290595deb
Autor:
Songping Wang, Tiffany H Dorsey, Atsushi Terunuma, Rick A Kittles, Stefan Ambs, Bernard Kwabi-Addo
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37928 (2012)
Aberrant DNA methylation is critical for development and progression of breast cancer. We investigated the association of CpG island methylation in candidate genes and clinicopathological features in 65 African-American (AA) and European-American (EA
Externí odkaz:
https://doaj.org/article/321ee8b960be4ec2865b06550a8d5442
Autor:
Matthew P Vaughn, Debika Biswal Shinohara, Nicole Castagna, Jessica L Hicks, George Netto, Angelo M De Marzo, Traci J Speed, Zachery R Reichert, Bernard Kwabi-Addo, Colin J Henderson, C Roland Wolf, Srinivasan Yegnasubramanian, William G Nelson
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25707 (2011)
Glutathione S-transferases (GSTs) metabolize drugs and xenobiotics. Yet despite high protein sequence homology, expression of π-class GSTs, the most abundant of the enzymes, varies significantly between species. In mouse liver, hepatocytes exhibit h
Externí odkaz:
https://doaj.org/article/07fb1536d03c43a3a08c8dafe7106551
Autor:
Woonbok Chung, Bernard Kwabi-Addo, Michael Ittmann, Jaroslav Jelinek, Lanlan Shen, Yinhua Yu, Jean-Pierre J Issa
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2079 (2008)
DNA hypermethylation is a common epigenetic abnormality in cancer and may serve as a useful marker to clone cancer-related genes as well as a marker of clinical disease activity. To identify CpG islands methylated in prostate cancer, we used methylat
Externí odkaz:
https://doaj.org/article/cdb1209e38b545868eff5cbc82f9a698