Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bernard Kok Bang Lee"'
Autor:
Chai Phei Gan, Bernard Kok Bang Lee, Shin Hin Lau, Thomas George Kallarakkal, Zuraiza Mohamad Zaini, Bryan Kit Weng Lye, Rosnah Binti Zain, Hans Prakash Sathasivam, Joe Poh Sheng Yeong, Natalia Savelyeva, Gareth Thomas, Christian H. Ottensmeier, Hany Ariffin, Sok Ching Cheong, Kue Peng Lim
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Oral potentially malignant disorders (OPMD) are precursors of oral squamous cell carcinoma (OSCC), and the presence of oral epithelial dysplasia (OED) in OPMD confers an increased risk of malignant transformation. Emerging evidence has indicated a ro
Externí odkaz:
https://doaj.org/article/c922d4cc37a2451ca4be9978be7c9737
Autor:
Hany Ariffin, Gareth Thomas, Joe Poh Sheng Yeong, Chai Gan, Bernard Kok Bang Lee, Shin Hin Lau, Thomas George Kallarakkal, Zuraiza Mohamad Zaini, Rosnah Binti Zain, Hans Prakash Sathasivam, Natalia Savelyeva, Christian Ottensmeier, Sok Ching Cheong, Kue Peng Lim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/2a824340435443b183baf7b04fea4b30
Autor:
Nur Syafinaz Zainal, Bernard Kok Bang Lee, Zheng Wei Wong, Iuan Sheau Chin, Pei San Yee, Chai Phei Gan, Kein Seong Mun, Zainal Ariff Abdul Rahman, J. Silvio Gutkind, Vyomesh Patel, Sok Ching Cheong
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 2, Pp 264-275 (2019)
Objective Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including
Externí odkaz:
https://doaj.org/article/0cbed0837b6a4998adfdc5845bbf03bb
Autor:
Joe Poh Sheng Yeong, Hans Prakash Sathasivam, Kue Peng Lim, Shin Hin Lau, Zuraiza Mohamad Zaini, Christian H. Ottensmeier, Sok Ching Cheong, Chai Gan, Bernard Kok Bang Lee, Hany Ariffin, Thomas George Kallarakkal, Natalia Savelyeva, Rosnah Binti Zain, Gareth J. Thomas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundPatients with oral potentially malignant disorders (OPMD) having moderate or severe oral epithelial dysplasia (OED) have a greater risk of developing oral squamous cell carcinoma (OSCC) compared to mild OED with an odds ratio of 2.4.1 The i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2027599c034a9fbc7bf54739ebee13
https://doaj.org/article/2a824340435443b183baf7b04fea4b30
https://doaj.org/article/2a824340435443b183baf7b04fea4b30
Publikováno v:
Advances in Molecular Pathology. 2:201-213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95bf16b031e0cbb5cb04b655fffca7ad
https://doi.org/10.1016/j.yamp.2019.07.014
https://doi.org/10.1016/j.yamp.2019.07.014
Autor:
Pei San Yee, Chai Phei Gan, Vyomesh Patel, Kein Seong Mun, Nur Syafinaz Zainal, Mannil Thomas Abraham, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Sok Ching Cheong, Bernard Kok Bang Lee
Publikováno v:
Targeted Oncology. 14:223-235
Given that aberrant activation of epidermal growth factor receptor family receptors (ErbB) is a common event in oral squamous cell carcinoma, and that high expression of these receptor proteins is often associated with poor prognosis, this rationaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddf4941ccb03ba1937665ea0447521d
https://doi.org/10.1007/s11523-019-00626-8
https://doi.org/10.1007/s11523-019-00626-8
Autor:
Chai Phei Gan, J. S. Gutkind, Stephen S. Prime, Z.A. Abdul Rahman, Muhammad Zaki Hidayatullah Fadlullah, Joon Liang Tan, Aik Choon Tan, Sok Ching Cheong, Jit Kang Chang, Tsung Fei Khang, Bernard Kok Bang Lee, Chee Sun Liew
Publikováno v:
Journal of Dental Research. 97:909-916
Head and neck cancer (HNC)–derived cell lines represent fundamental models for studying the biological mechanisms underlying cancer development and precision therapies. However, mining the genomic information of HNC cells from available databases r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bfab3d57ed37159b6a1b6c6cdb0fa2
https://doi.org/10.1177/0022034518759038
https://doi.org/10.1177/0022034518759038
Autor:
Nur Syafinaz Zainal, Kin Kit Sam, Zainal Ariff Abdul Rahman, Pei San Yee, Rosnah Binti Zain, Aik Choon Tan, Chai Phei Gan, Sok Ching Cheong, Vyomesh Patel, Bernard Kok Bang Lee
Publikováno v:
Cell Oncol (Dordr)
PURPOSE: Oral squamous cell carcinoma (OSCC) is a challenging disease to treat. Up to 50% of OSCC patients with advanced disease develop recurrences. Elucidation of key molecular mechanisms underlying OSCC development may provide opportunities to tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db788d8b20c77132dae9e1478004996
https://europepmc.org/articles/PMC7771307/
https://europepmc.org/articles/PMC7771307/
Autor:
Chai Phei Gan, Sok Ching Cheong, Pei San Yee, Vyomesh Patel, Hui Mei Lee, Bernard Kok Bang Lee, Gregory Michael Kelly, Muhammad Zaki Hidayatullah Fadlullah, Nur Syafinaz Zainal
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The use of EGFR inhibitors on oral squamous cell carcinoma (OSCC) as monotherapy yielded modest clinical outcomes and therefore would benefit from biomarkers that could predict which patient subsets are likely to respond. Here, we determined the effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2bba13a9d1784c0b40cea3f312dea5
https://pubmed.ncbi.nlm.nih.gov/30787334
https://pubmed.ncbi.nlm.nih.gov/30787334