Zobrazeno 1 - 10
of 430
pro vyhledávání: '"Bernard Klein"'
Autor:
Jean-François Rossi, Hao-Chun Chiang, Zhao-Yang Lu, Kalle Levon, Frits van Rhee, Karan Kanhai, David C. Fajgenbaum, Bernard Klein
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDysregulated interleukin (IL)-6 production can be characterised by the levels present, the kinetics of its rise and its inappropriate location. Rapid, excessive IL-6 production can exacerbate tissue damage in vital organs. In this situation
Externí odkaz:
https://doaj.org/article/555276582e234c2fa63005d0906264af
Autor:
Orianne Villard, Mathieu Armanet, Guilhem Couderc, Claire Bony, Jerome Moreaux, Daniele Noël, John DeVos, Bernard Klein, Jean-Luc Veyrune, Anne Wojtusciszyn
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background Mesenchymal stromal cells (MSCs) represent an interesting tool to improve pancreatic islet transplantation. They have immunomodulatory properties and secrete supportive proteins. However, the functional properties of MSCs vary acc
Externí odkaz:
https://doaj.org/article/7a1ad9f4af16455fb369a2c6553641fb
Autor:
Orianne Villard, Mathieu Armanet, Guilhem Couderc, Claire Bony, Jerome Moreaux, Daniele Noël, John De Vos, Bernard Klein, Jean-Luc Veyrune, Anne Wojtusciszyn
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e6480e51708449368107cddab8f00d4d
Autor:
Michel Jourdan, Nicolas Robert, Maïlys Cren, Coraline Thibaut, Christophe Duperray, Alboukadel Kassambara, Michel Cogné, Karin Tarte, Bernard Klein, Jérôme Moreaux
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179793 (2017)
FCRL4 is an immunoregulatory receptor that belongs to the Fc receptor-like (FCRL) family. In healthy individuals, FCRL4 is specifically expressed by memory B cells (MBCs) localized in sub-epithelial regions of lymphoid tissues. Expansion of FCRL4+ B
Externí odkaz:
https://doaj.org/article/8e049d4f5f5440368022b6b2c8ea4cba
Autor:
Claire Gourzones, Céline Bellanger, Sylvain Lamure, Ouissem Karmous Gadacha, Elvira Garcia De Paco, Laure Vincent, Guillaume Cartron, Bernard Klein, Jérôme Moreaux
Publikováno v:
Cancers, Vol 11, Iss 4, p 439 (2019)
Background: Multiple myeloma (MM) is the second most common hematological cancer after lymphoma. It is characterized by the accumulation of clonal malignant plasma cells within the bone marrow. The development of drug resistance remains a major probl
Externí odkaz:
https://doaj.org/article/f3f7af4d77b44915bf4abae271c36971
Autor:
Niels Weinhold, Tobias Meissner, David C Johnson, Anja Seckinger, Jérôme Moreaux, Asta Försti, Bowang Chen, Jolanta Nickel, Daniel Chubb, Andrew C. Rawstron, Chi Doughty, Nasrin B. Dahir, Dil B. Begum, Kwee Young, Brian A. Walker, Per Hoffmann, Marcus M. Nöthen, Faith E. Davies, Bernard Klein, Hartmut Goldschmidt, Gareth J. Morgan, Richard S Houlston, Dirk Hose, Kari Hemminki
Publikováno v:
Haematologica, Vol 100, Iss 3 (2015)
Externí odkaz:
https://doaj.org/article/3d6b17a794544904ae27d968f73c7dc1
Autor:
Alboukadel Kassambara, Thierry Rème, Michel Jourdan, Thierry Fest, Dirk Hose, Karin Tarte, Bernard Klein
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 1, p e1004077 (2015)
DNA microarrays have considerably helped to improve the understanding of biological processes and diseases. Large amounts of publicly available microarray data are accumulating, but are poorly exploited due to a lack of easy-to-use bioinformatics res
Externí odkaz:
https://doaj.org/article/e23bad4fd7c9439d82678f7827bcd8d9
Autor:
Alboukadel Kassambara, Matthieu Schoenhals, Jérôme Moreaux, Jean-Luc Veyrune, Thierry Rème, Hartmut Goldschmidt, Dirk Hose, Bernard Klein
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62752 (2013)
High throughput DNA microarray has made it possible to outline genes whose expression in malignant plasma cells is associated with short overall survival of patients with Multiple Myeloma (MM). A further step is to elucidate the mechanisms encoded by
Externí odkaz:
https://doaj.org/article/508612106bfa427fa972fa82872ef90a
Autor:
Thomas M Moehler, Anja Seckinger, Dirk Hose, Mindaugas Andrulis, Jèrôme Moreaux, Thomas Hielscher, Martina Willhauck-Fleckenstein, Anette Merling, Uta Bertsch, Anna Jauch, Hartmut Goldschmidt, Bernard Klein, Reinhard Schwartz-Albiez
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83719 (2013)
The glycome, i.e. the cellular repertoire of glycan structures, contributes to important functions such as adhesion and intercellular communication. Enzymes regulating cellular glycosylation processes are related to the pathogenesis of cancer includi
Externí odkaz:
https://doaj.org/article/dd627b36aef541cdad326231c4f55164
Autor:
Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Brian A. Walker, Alexei Protopopov, Thierry Reme, Franck Pellestor, Véronique Pantesco, Anna Jauch, Gareth Morgan, Hartmut Goldschmidt, Bernard Klein
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
Background Genetic abnormalities are common in patients with multiple myeloma, and may deregulate gene products involved in tumor survival, proliferation, metabolism and drug resistance. In particular, translocations may result in a high expression o
Externí odkaz:
https://doaj.org/article/fd6ca935222847628b042480e0dad387