Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Bernard J.C. Macatangay"'
Publikováno v:
Journal of Virus Eradication, Vol 4, Iss 4, Pp 209-214 (2018)
Despite significant advances in the understanding of HIV-1 infection, a cure remains out of reach. This is, in part, due to a long-lived HIV-1 reservoir in resting CD4+ T cells, which do not express viral antigens, and thus are invisible to the immun
Externí odkaz:
https://doaj.org/article/53bb0b52f8f44b8e8cd7a383e3a6240e
Autor:
Curtis Dobrowolski, Michael F. Para, Jonathan Karn, Joshua C. Cyktor, Edward P. Acosta, Ronald T. Mitsuyasu, Joseph Hesselgesser, Joan Dragavon, Evgenia Aga, Rajesh T. Gandhi, Bernard J.C. Macatangay, John W. Mellors, Deborah McMahon, Catherine Godfrey, Lu Zheng
Publikováno v:
J Infect Dis
Background Romidepsin (RMD) is a histone deacetylase inhibitor reported to reverse HIV-1 latency. We sought to identify doses of RMD that were safe and induced HIV-1 expression. Methods Enrollees had HIV-1 RNA Results In the single-dose cohorts 1–3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a234f1b2b2d2524ea5ab6ea78e5f3f29
https://doi.org/10.1093/infdis/jiaa777
https://doi.org/10.1093/infdis/jiaa777
Autor:
Lynsay MacLaren, Alan L. Landay, Michael C. Keefer, Jintanat Anaworanich, Eugene Kroon, Steven G. Deeks, Davey M. Smith, Evgenia Aga, Bernard J.C. Macatangay, Ronald J. Bosch, Robert W. Coombs, Rajesh T. Gandhi, Mark A. Pilkinton, John W. Mellors, Liz Barr, Edward P. Acosta, Jonathan Z. Li, Lawrence Fox
Publikováno v:
Clinical infectious diseases, 74(5), 865-870. Oxford University Press
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 5
Clin Infect Dis
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 5
Clin Infect Dis
BackgroundDevelopment of human immunodeficiency virus (HIV) remission strategies requires precise information on time to HIV rebound after treatment interruption, but there is uncertainty regarding whether modern antiretroviral therapy (ART) regimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94436829c6b8fc5b495b4cc8a8bc1451
https://pure.amc.nl/en/publications/time-to-viral-rebound-after-interruption-of-modern-antiretroviral-therapies(8bc3ebcb-3e5d-4334-9a70-8ed7997d06b5).html
https://pure.amc.nl/en/publications/time-to-viral-rebound-after-interruption-of-modern-antiretroviral-therapies(8bc3ebcb-3e5d-4334-9a70-8ed7997d06b5).html
Autor:
William David Hardy, Steven Hendrickx, Randall Tressler, Edgar T. Overton, Joseph J. Eron, Kendall F. Moseley, Maureen Furlong, Elizabeth Miller, Michael Messer, Constance A. Benson, Arrow trial team, Chanelle L Wimbish, Daniel R. Kuritzkes, Bernard J.C. Macatangay, Cheryl Jennings, Ronald J. Bosch, Danielle M Campbell, Ashley McKahnn
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes (1999)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758490fe81bcd49dd1b6fef74b866ec4
http://europepmc.org/articles/PMC8263135
http://europepmc.org/articles/PMC8263135
Autor:
Szu-Han Huang, Adam R. Ward, Joshua C. Cyktor, R. Brad Jones, Ronald J. Bosch, Rajesh T. Gandhi, Sheila M. Keating, John W. Mellors, Eva M. Stevenson, Allison S. Thomas, Joseph J. Eron, Bernard J.C. Macatangay, Deborah McMahon
BackgroundPeople with HIV (PWH) have persistently elevated levels of inflammation and immune activation despite suppressive antiretroviral therapy (ART), with specific biomarkers showing associations with non-AIDS-defining morbidities and mortality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0023700796b507e9f6cb6e7e94adc04f
https://doi.org/10.1101/2021.11.08.21266096
https://doi.org/10.1101/2021.11.08.21266096
Autor:
Matthew K Hensley, Jana L. Jacobs, Bernard J.C. Macatangay, Rahil Sethi, Ashwin Somasundaram, Feng Shan, Ghady Haidar, Brittany Staines, Anthony R. Cillo, Janet S. Lee, Linda J. Rennick, Amy Heaps, Anuradha Ray, Michele D. Sobolewski, William Bain, Barbara Methé, Tullia C. Bruno, Prabir Ray, Dario A. A. Vignali, John W. Mellors, William E. Schwarzmann, Georgios D Kitsios, W. Paul Duprex, Urvi M. Parikh, Creg J. Workman, Carly Cardello, Cynthia Klamar-Blain, Mounzer Agha, Sham Nambulli, Kevin D. McCormick, Mark S. Ladinsky, Pamela J. Bjorkman, Alison Morris
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
A chimeric antigen receptor-modified T-cell therapy recipient developed severe coronavirus disease 2019, intractable RNAemia, and viral replication lasting >2 months. Premortem endotracheal aspirate contained >2 × 1010 severe acute respiratory syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f1eae762c64dfc3bf3ebdefe98e881
https://resolver.caltech.edu/CaltechAUTHORS:20210201-145608486
https://resolver.caltech.edu/CaltechAUTHORS:20210201-145608486
Publikováno v:
Open Forum Infectious Diseases
Human immunodeficiency virus (HIV) is associated with an increased risk of age-associated comorbidities and mortality compared to people without HIV. This has been attributed to HIV-associated chronic inflammation and immune activation despite viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe8c102e231e4bbc9c4fc1c1dc8d5d5
https://doi.org/10.1093/ofid/ofab396
https://doi.org/10.1093/ofid/ofab396
Autor:
Wendy S. Post, Valentina Stosor, Bernard J.C. Macatangay, Joseph B. Margolick, Nikolas Wada, Elizabeth C. Breen
Publikováno v:
J Gerontol A Biol Sci Med Sci
Background C-reactive protein (CRP) is an inflammatory biomarker associated with all-cause mortality and morbidities such as cardiovascular disease. CRP is increased with HIV infection and thought to increase with age, though trajectories of CRP with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36817c6ee071b36ae222b1fc93e57cdb
https://europepmc.org/articles/PMC9255683/
https://europepmc.org/articles/PMC9255683/
Autor:
Benigno Rodriguez, Alison L. Pelger, Todd T. Brown, Bernard J.C. Macatangay, Alan L. Landay, Douglas Kitch, Ronald J. Bosch, Robert Asaad, Netanya S. Utay, Michael M. Lederman, Dominic Dorazio, Jane E. Baum
Publikováno v:
Journal of Virus Eradication
Journal of Virus Eradication, Vol 5, Iss 1, Pp 28-32 (2019)
Journal of Virus Eradication, Vol 5, Iss 1, Pp 28-32 (2019)
Objectives The relationship between lipid levels in plasma and inflammatory indices is complex and fatty meals alter plasma inflammatory markers in people with diabetes. There is interest in monitoring the effects of interventions on plasma inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c88786519d5fb1930706a456191ac4b
http://europepmc.org/articles/PMC6362905
http://europepmc.org/articles/PMC6362905
Autor:
Adam R. Ward, Thomas R Dilling, Allison S. Thomas, Christina M. Lalama, Andrea Gramatica, Bernard J.C. Macatangay, Szu-Han Huang, Pragya Khadka, Joshua C. Cyktor, John K. Bui, Eva M. Stevenson, Deborah McMahon, R. Brad Jones, Ronald Truong, Winiffer D. Conce Alberto, John W. Mellors, Guinevere Q. Lee, Talia M. Mota, Ali Danesh, Ronald J. Bosch, Joseph J. Eron, Sandra Terry, Rajesh T. Gandhi
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
JCI Insight
JCI Insight
Antiretroviral therapies (ARTs) abrogate HIV replication; however, infection persists as long-lived reservoirs of infected cells with integrated proviruses, which reseed replication if ART is interrupted. A central tenet of our current understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c689e1fb10e42c73b958dbfc7d118b12
https://doi.org/10.1172/jci.insight.142640
https://doi.org/10.1172/jci.insight.142640