Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Bernard Gerrard"'
Use of Denaturing HPLC to Map Human and Murine Genes and to Validate Single-Nucleotide Polymorphisms
Publikováno v:
BioTechniques, Vol 28, Iss 4, Pp 740-745 (2000)
Linkage mapping has been extensively applied in the murine and human genomes. It remains a powerful approach to mapping genes and identifying genetic variants. As genome efforts identify large numbers of single-nucleotide polymorphisms, it will be cr
Externí odkaz:
https://doaj.org/article/7fa2fb00b023495cae90ab45b441e0c9
Publikováno v:
Genomics. 66:204-212
Changes that occur during tumor promotion, the rate-limiting phase of multistep carcinogenesis, may offer the best targets for prevention of cancer or reversal of early disease. The murine epidermal JB6 promotion-sensitive (P+) and -resistant (P-) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010ed1a2e2579ff491f04c345c7d85de
https://doi.org/10.1006/geno.2000.6210
https://doi.org/10.1006/geno.2000.6210
Autor:
Rando Allikmets, Maria D. Ramos, David Reich, Marios Kambouris, Stephen J. O'Brien, David Goldstein, Nicholas G. Martin, David Goldman, Michael Dean, Hyoung Doo Shin, Michael Aseev, Mireille Claustres, Cheryl A. Winkler, Andres Metspalu, Bernard Gerrard, Susanne Morlot, Francesco S. di Giovine, J. Claiborne Stephens, Luba Kalaydjieva, Georgios Nasioulas, Harry Ostrer, David L. Duffy, Gordon W. Duff, Mary Carrington, Paolo Gasparini, Carole Oddoux, Michael Malasky, Gavin A. Huttley, Jörg Schmidtke, Damjan Glavač, Maria Tzetis, Matthew Hanson, David Chandler, Michael W. Smith, Lynn M. Schriml, Xavier Estivill, Hiljar Sibul, Vladislav S Baranov, Emmanuel Kanavakis
Publikováno v:
The American Journal of Human Genetics. 62(6):1507-1515
The CCR5-Delta32 deletion obliterates the CCR5 chemokine and the human immunodeficiency virus (HIV)-1 coreceptor on lymphoid cells, leading to strong resistance against HIV-1 infection and AIDS. A genotype survey of 4,166 individuals revealed a cline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e934c11a26f297a160452316da1433
Autor:
Teri Kissner, Bernard Gerrard, Mary Carrington, Stephen J. O'Brien, Sergey Ivanov, Michael Dean
Publikováno v:
The American Journal of Human Genetics. 61:1261-1267
The CCR5 gene encodes a cell-surface chemokine-receptor molecule that serves as a coreceptor for macrophage-tropic strains of HIV-1. Mutations in this gene may alter expression or function of the protein product, thereby altering chemokine binding/si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457d011d5ab76656ea9a5752dd6739f8
https://doi.org/10.1086/301645
https://doi.org/10.1086/301645
Autor:
Abirami Chidambaram, Mae R. Gailani, Allen E. Bale, Bernard Gerrard, Michael Dean, Claudia Stewart, Alisa M. Goldstein, Ilya Chumakov
Publikováno v:
Genes, Chromosomes and Cancer. 18:212-218
Gorlin's syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by a familial or hereditary predisposition to basal cell carcinomas (generally multiple and of early onset), odontogenic keratocysts (ja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbdeb6ca99a09feb36a4f05a753085d
https://doi.org/10.1002/(sici)1098-2264(199703)18:3<212::aid-gcc7>3.0.co
https://doi.org/10.1002/(sici)1098-2264(199703)18:3<212::aid-gcc7>3.0.co
Publikováno v:
Human Molecular Genetics. 5:1649-1655
As an approach to characterizing all human ATP-binding cassette (ABC) superfamily genes, a search of the human expressed sequence tag (EST) database was performed using sequences from known ABC genes. A total of 105 clones, containing sequences of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1d3f0bf1b88b0765832c61e4b51407
https://doi.org/10.1093/hmg/5.10.1649
https://doi.org/10.1093/hmg/5.10.1649
Autor:
Bernard Gerrard, Metka Ravnik-Glavač, Rando Allikmets, Neal G. Copeland, William S. Modi, Michael Dean, Debra J. Gilbert, Nancy A. Jenkins, D. Glavac
Publikováno v:
Mammalian Genome. 6:114-117
Analysis of the human expressed sequence tag (EST) database identified four clones that contain sequences of previously uncharacterized genes, members of the ATP-binding cassette (ABC) superfamily. Two new ABC genes (EST20237, 31252) are located at C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0d60272cb4e287ad8f6e33dad6fd02
https://doi.org/10.1007/bf00303254
https://doi.org/10.1007/bf00303254
Autor:
Claudia Stewart, Susan Michaelis, Amy Kistler, Jeff Strathern, Rando Allikmets, Bernard Gerrard, Brenda Shafer, Michael Dean
Publikováno v:
Yeast. 10:377-383
ATP-binding cassette (ABC) transporters share significant sequence identity within their ATP-binding domains. Degenerate oligonucleotides based on highly conserved portions of the ATP-binding domain genes were used to clone portions of two members of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb23881c89158aca67951ee1a6a5a92d
https://doi.org/10.1002/yea.320100310
https://doi.org/10.1002/yea.320100310
Publikováno v:
Gene. 136:231-236
Using degenerate oligodeoxyribonucleotides from conserved regions of the gene family encoding ATP-binding domain of the active transporter, two new Escherichia coli genes were identified. The first of the genes, named mdl (multidrug resistance- l ike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de2d7a0ac479710df742b7146eaaccf
https://doi.org/10.1016/0378-1119(93)90470-n
https://doi.org/10.1016/0378-1119(93)90470-n
Autor:
Lynne M. Quittell, Bernard Gerrard, V S Baranov, Marga Belle White, Douglas S. Holsclaw, Nicolai I. Kapronov, Ornella Castiglione, Tatyana E. Ivaschenko, Claudia Stewart, Leslie J. Krueger, Gianfranco Sebastio, Gregory Dolganov, Michael Dean
Publikováno v:
Genomics. 10:266-269
We have identified three new frameshift mutations in the CFTR gene in patients with cystic fibrosis (CF). The first one involves the deletion of an adenine nucleotide in exon 4 in an African-American patient (CF444delA), the second involves the inser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e5fc20fbc50d33e0107347d742c3ba
https://doi.org/10.1016/0888-7543(91)90510-l
https://doi.org/10.1016/0888-7543(91)90510-l