Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Bernard Do"'
Autor:
Moïse Houssen, Philippe-Henri Secretan, Loup Nobilet, Kilian Jossot, Laura Guichard, Cédric Mwamba, David Ngy, Lamia Hassani, Audrey Solgadi, Marie Antignac, Bernard Do, Helga Junot, Hassane Sadou Yayé
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 977 (2024)
Doravarine (DOR) is an antiviral drug with a marketed authorization for the management of occupational blood and body fluid exposure. The currently existing packaging, consisting of multiple unit bottles comprising 30 tablets, is not fully appropriat
Externí odkaz:
https://doaj.org/article/f9eb9dc8120d4505b41e25d28cecd492
Autor:
Shruti Mohan, Louis-Antoine Barel, Djamal Eddine Benrahla, Bernard Do, Qiyue Mao, Hiroaki Kitagishi, Michael Rivard, Roberto Motterlini, Roberta Foresti
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106770- (2023)
Metal carbonyls have been developed as carbon monoxide-releasing molecules (CO-RMs) to deliver CO for therapeutic purposes. The manganese-based CORM-401 has been recently reported to exert beneficial effects in obese animals by reducing body weight g
Externí odkaz:
https://doaj.org/article/e508d3eb7d174583b8fa572062e24b22
Autor:
Maxime Annereau, Marina Vignes, Lucas Denis, André Rieutord, François-Xavier Legrand, François Rioblanc, Muriel Paul, Jacques Grill, Philippe-Henri Secretan, Bernard Do
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2371 (2023)
Glioblastoma is one of the most common and aggressive forms of brain tumor, a rare disease for which there is a great need for innovative therapies. ONC201, a new drug substance, has been used in a compassionate treatment program where the choice of
Externí odkaz:
https://doaj.org/article/9e3bd91d566b4fa4b02f65f9cb81c2fa
Autor:
Maxime Annereau, Marina Vignes, Tahar Sif Eddine Bouchema, Lucas Denis, Audrey Solgadi, Victoire Vieillard, Muriel Paul, André Rieutord, Jacques Grill, Philippe-Henri Secretan, Bernard Do
Publikováno v:
Chemosensors, Vol 11, Iss 5, p 294 (2023)
ONC201 (dordaviprone) is a new drug substance used in a compassionate manner to treat patients with glioblastoma. Given the clinical context and the particularly promising preclinical results, we have been asked by the medical authorities to make a f
Externí odkaz:
https://doaj.org/article/45279da8d61e46dcb91e2aa5fc1d0212
Autor:
Philippe-Henri Secretan, Victoire Vieillard, Olivier Thirion, Maxime Annereau, Hassane Sadou Yayé, Alain Astier, Muriel Paul, Thibaud Damy, Bernard Do
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 424 (2023)
In vitro studies have shown that epigallocatechin gallate (EGCG), the most potent antioxidant of the green tea polyphenol catechins, is able to effectively prevent the formation of amyloid plaques and induce their clearance. However, its high chemica
Externí odkaz:
https://doaj.org/article/666c1f6220f941cb85f56b4679579456
Autor:
Tahar Sif eddine Bouchema, Maxime Annereau, Victoire Vieillard, Raphael Boquet, Gisele Abreu Coelho, Florence Castelli, Audrey Solgadi, Muriel Paul, Najet Yagoubi, Philippe-Henri Secretan, Bernard Do
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2651 (2022)
Selumetinib is administered orally in capsule form and is indicated for the treatment of neurofibromatosis. To facilitate dosage adjustments, liquid preparations, such as solutions or suspensions, are to be developed. This led, first, to determine th
Externí odkaz:
https://doaj.org/article/3af45a625be546e5b1670badf7227520
Autor:
Philippe-Henri Secretan, Maxime Annereau, Willy Kini-Matondo, Bastien Prost, Jade Prudhomme, Lina Bournane, Muriel Paul, Najet Yagoubi, Hassane Sadou-Yayé, Bernard Do
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1720 (2022)
Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID®. Although knowledge of nirmatrelvir’s intrinsic stability may be useful for any potenti
Externí odkaz:
https://doaj.org/article/e645376c1ce44df9a2bedc04db8ab10d
Autor:
Guillaume Le Guyader, Bernard Do, Ivo B. Rietveld, Pascale Coric, Serge Bouaziz, Jean-Michel Guigner, Philippe-Henri Secretan, Karine Andrieux, Muriel Paul
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 569 (2022)
Facial angiofibromas (FA) are one of the most obvious cutaneous manifestations of tuberous sclerosis complex. Topical rapamycin for angiofibromas has been reported as a promising treatment. Several types of vehicles have been used hitherto, but polym
Externí odkaz:
https://doaj.org/article/51227dd701c843f8b047dc46ce9e5319
Autor:
Marie Antignac, Philippe-Henri Secretan, Najet Yagoubi, Mélisande Bernard, Marie Cécile Perier, Jean Laurent Takombe, Dadhi Balde, Roland N'Guetta, Méo Stéphane Ikama, Patrice Zabsonre, Abdallahi Sidi Aly, Bernard Do
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Objectives The incidence of cardiovascular diseases is increasing and there is a growing need to provide access to quality cardio drugs in Africa. In the SEVEN study, we analysed 1530 cardiovascular drug samples randomly collected from 10 African cou
Externí odkaz:
https://doaj.org/article/d130ab2228fd40d0a3b33747f1d5175b
Autor:
Philippe-Henri Secretan, Olivier Thirion, Hassane Sadou Yayé, Thibaud Damy, Alain Astier, Muriel Paul, Bernard Do
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1242 (2021)
Because of its antioxidant, antimutagenic, and anti-infectious properties, epigallocatechin gallate (EGCG) is the most interesting compound among the green tea catechins polyphenols. However, its health effects are inconclusive due to its very low bi
Externí odkaz:
https://doaj.org/article/1a52ae2200de42d7a80b59ceeebf4ddf