Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Bernard Desbat"'
A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis
Autor:
Benoît Hastoy, Pier A. Scotti, Alexandra Milochau, Zahia Fezoua-Boubegtiten, Jorge Rodas, Rémi Megret, Bernard Desbat, Michel Laguerre, Sabine Castano, David Perrais, Patrik Rorsman, Reiko Oda, Jochen Lang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Exocytosis depends on cytosolic domains of SNARE proteins but the function of the transmembrane domains (TMDs) in membrane fusion remains controversial. The TMD of the SNARE protein synaptobrevin2/VAMP2 contains two highly conserved small am
Externí odkaz:
https://doaj.org/article/01d582e4c0cb4700b6227323642fc200
Autor:
Zahia Fezoua-Boubegtiten, Bernard Desbat, Reiko Oda, Jochen Lang, Katell Bathany, Alexandra Milochau, Sabine Castano, Benoit Hastoy, Pier Scotti
Publikováno v:
Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676. ⟨10.1016/j.bbamem.2018.12.011⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676. ⟨10.1016/j.bbamem.2018.12.011⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676
International audience; Neurotransmitter and hormone exocytosis depends on SNARE protein transmembrane domains and membrane lipids but their interplay is poorly understood. We investigated the interaction of the structure of VAMP2, a vesicular transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1c494488f0cfab12a5a2b0bc89bdf1
https://doi.org/10.1016/j.bbamem.2018.12.011
https://doi.org/10.1016/j.bbamem.2018.12.011
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 174
Neurocalcin delta (NCALD) is a member of the neuronal calcium sensors protein family. In the retina, NCALD is expressed by ganglion and amacrine cells. NCALD is composed of 4 EF-hand motifs but only 3 of them may bind calcium. The binding of calcium
Autor:
Eric Demers, Line Cantin, Elodie Boisselier, Nicolas Belley, S. Champagne, Christian Salesse, D. Blaudez, Bernard Desbat, Philippe Calvez, Habib Horchani
Publikováno v:
Biochemistry. 54:2560-2570
Retinitis pigmentosa 2 (RP2) is an ubiquitary protein of 350 residues. The N-terminus of RP2 contains putative sites of myristoylation and palmitoylation. The dually acylated protein is predominantly localized to the plasma membrane. However, clinica
Autor:
Line Cantin, Christian Salesse, Bernard Desbat, Sarah C. Bernier, Mustapha Lhor, Habib Horchani, Sylvain Bussières
Publikováno v:
Advances in Colloid and Interface Science. 207:223-239
Membrane binding of proteins such as short chain dehydrogenases reductases or tail-anchored proteins relies on their N- and/or C-terminal hydrophobic transmembrane segment. In this review, we propose guidelines to characterize such hydrophobic peptid
Autor:
Eric Ennifar, Brice Kauffmann, Paul Claudon, Sabine Castano, Dominique Cavagnat, Gilles Guichard, Nagendar Pendem, Céline Douat, Bernard Desbat, Michel Laguerre
Publikováno v:
Journal of the American Chemical Society. 135:4884-4892
Aliphatic N,N'-linked oligoureas are peptidomimetic foldamers that adopt a well-defined helical secondary structure stabilized by a collection of remote three-center H-bonds closing 12- and 14-membered pseudorings. Delineating the rules that govern h
Autor:
Isabel D. Alves, Sophie Lecomte, Christophe Cullin, Pierre Bonnafous, Bernard Desbat, Karine Berthelot, Ha Phuong Ta, Olivier Lambert, Bénédicte Coulary-Salin, Sabine Castano
Publikováno v:
Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2012, 1818 (9), pp.2325-2334. ⟨10.1016/j.bbamem.2012.04.013⟩
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2012, 1818 (9), pp.2325-34
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2012, 1818 (9), pp.2325-2334. ⟨10.1016/j.bbamem.2012.04.013⟩
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2012, 1818 (9), pp.2325-34
article i nfo Article history: Many studies have pointed out the interaction between amyloids and membranes, and their potential in- volvement in amyloid toxicity. Previously, we generated a yeast toxic amyloid mutant (M8) from the harm- less amyloid
Autor:
Catherine Manin, Bernard Desbat, Julie Bonvin, Frédéric Greco, Catherine Estèves, Vanille J. Greiner, Eric Larquet, Andrey S. Klymchenko, Yves Mély, Frédéric Ronzon
Publikováno v:
Vaccine
Vaccine, Elsevier, 2012, 30, pp.5240-5245
Vaccine, Elsevier, 2012, 30, pp.5240-5245
Current Hepatitis B vaccines are based on recombinant Hepatitis B surface antigen (HBsAg) virus-like particles adsorbed on aluminium (Al) gel. These particles exhibit a lipoprotein-like structure with about 70 protein S molecules in association with
Autor:
Tino Krell, Marie-Claire Nicolaï, Eloïse Lancelot, Bernard Desbat, Fred Vogel, Frédéric Ronzon, Michel Chevalier
Publikováno v:
Langmuir. 27:13675-13683
The production protocol of many whole cell/virion vaccines involves an inactivation step with β-propiolactone (BPL). Despite the widespread use of BPL, its mechanism of action is poorly understood. Earlier work demonstrated that BPL alkylates nucleo
Autor:
Reiko Oda, Roni Kiagus-Armad, Aurélie Brizard, Richard A. Blatchly, Bernard Desbat, Claire Tang
Publikováno v:
Chemistry - A European Journal. 17:9999-10009
The confinement of anionic oligoalanine peptides at the surface of cationic membranes can cooperatively reinforce peptide/peptide interactions and induce secondary-structure formation, and, reciprocally, induce chirality expression of the membrane at