Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bernard D Hummel"'
Autor:
Ines Greco, Bernard D. Hummel, Jaspreet Vasir, Jeffrey L. Watts, Jason Koch, Johannes E. Hansen, Hanne Mørck Nielsen, Peter Damborg, Paul R. Hansen
Publikováno v:
Molecules, Vol 23, Iss 3, p 630 (2018)
Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents, but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic residues such as peptoids (oligomers of N-alkylglycines) provides the po
Externí odkaz:
https://doaj.org/article/64a07e1c773342c589278a9e685829a6
Autor:
Paul R. Hansen, Bernard D Hummel, Elin Holmedal, Jeffrey L. Watts, Johan Svenson, Håvard Jenssen, Natalia Molchanova, Joakim Håkansson, Ines Greco
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Greco, I, Molchanova, N, Holmedal, E, Jenssen, H, Hummel, B D, Watts, J L, Håkansson, J, Hansen, P R & Svenson, J 2020, ' Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides ', Scientific Reports, vol. 10, 13206 . https://doi.org/10.1038/s41598-020-69995-9
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Greco, I, Molchanova, N, Holmedal, E, Jenssen, H, Hummel, B D, Watts, J L, Håkansson, J, Hansen, P R & Svenson, J 2020, ' Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides ', Scientific Reports, vol. 10, 13206 . https://doi.org/10.1038/s41598-020-69995-9
The use of non-standard toxicity models is a hurdle in the early development of antimicrobial peptides towards clinical applications. Herein we report an extensive in vitro and in vivo toxicity study of a library of 24 peptide-based antimicrobials wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783b769cbed5d1b4894a2bd83e50a34e
https://doi.org/10.1038/s41598-020-69995-9
https://doi.org/10.1038/s41598-020-69995-9
Autor:
Paul R. Hansen, Jeffrey L. Watts, Bernard D Hummel, Peter Damborg, Jason Koch, Ines Greco, Jaspreet Vasir, Johannes E. Hansen, Hanne Mørck Nielsen
Publikováno v:
Molecules; Volume 23; Issue 3; Pages: 630
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Greco, I, Hummel, B D, Vasir, J, Watts, J L, Koch, J, Hansen, J E, Nielsen, H M, Damborg, P P & Hansen, P R 2018, ' In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma ', Molecules, vol. 23, no. 3, 630 . https://doi.org/10.3390/molecules23030630
Molecules, Vol 23, Iss 3, p 630 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Greco, I, Hummel, B D, Vasir, J, Watts, J L, Koch, J, Hansen, J E, Nielsen, H M, Damborg, P P & Hansen, P R 2018, ' In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma ', Molecules, vol. 23, no. 3, 630 . https://doi.org/10.3390/molecules23030630
Molecules, Vol 23, Iss 3, p 630 (2018)
Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents, but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic residues such as peptoids (oligomers of N-alkylglycines) provides the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19e076e8da1e55198b0406f8ba8ac3b
Autor:
Debra J. Woods, Xin Zhou, David P. Thompson, Alan A. Marchiondo, Christopher S. Knauer, Matthew J. Zaya, Steven X. Hu, Julie K. Lorenz, Wendy Collard, Bernard D Hummel, Dawn A. Merritt, Jinxia Nancy Deng
Publikováno v:
The Journal of parasitology. 100(6)
The objective of the current study was to establish an in vitro screen and a highly sensitive analytical assay to delineate key physicochemical properties that favor compound bioaccumulation in the L3 life stage of a Haemonchus contortus isolate. Tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116b2400eea8841a60fb0d2ab2dd7969
https://pubmed.ncbi.nlm.nih.gov/25116000
https://pubmed.ncbi.nlm.nih.gov/25116000