Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Bernard Bouscarel"'
Autor:
Amy Nguyen, Bernard Bouscarel
Publikováno v:
Cellular Signalling. 20:2180-2197
Bile acids are mainly recognized for their role in dietary lipid absorption and cholesterol homeostasis. However, recent progress in bile acid research suggests that bile acids are important signaling molecules that play a role in glucose homeostasis
Publikováno v:
American Journal of Physiology-Cell Physiology. 295:C1230-C1237
Glucagon receptor (GR) activity and expression are altered in several diseases, including Type 2 diabetes. Previously, we investigated the mechanism of GR desensitization and internalization. The present study focused on the fate of internalized GR.
Autor:
Frances P. Noonan, Gerard M. J. Beijersbergen van Henegouwen, Steven A. J. IJland, Dan Hug, Bernard Bouscarel, Edward C. De Fabo, Susan Ceryak, David P. T. Steenvoorden
Publikováno v:
Photochemistry and Photobiology. 67:222-226
Ultraviolet B (UVB, 290-320 nm) radiation initiates in vivo a dose- and wavelength-dependent down regulation of cell-mediated immunity. An action spectrum for UV-induced immunosuppression indicated that the photoreceptor for this effect is urocanic a
Autor:
Kelli Chapin-Kennedy, Lada Krilov, Tadashi Ikegami, Bernard Bouscarel, Jianping Meng, Bhumika Patel
Publikováno v:
Endocrinology. 147:5294-5302
Dihydroxy bile acids like chenodeoxycholic acid (CDCA) induce heterologous glucagon receptor desensitization. We previously demonstrated that protein kinase C (PKC) was activated by certain bile acids and mediated the CDCA-induced decrease in glucago
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 291:G275-G287
The aim was to identify the specific PKC isoform(s) and their mechanism of activation responsible for the modulation of cAMP production by bile acids in human dermal fibroblasts. Stimulation of fibroblasts with 25-100 microM of chenodeoxycholic acid
Autor:
Yining Zhang, Yasushi Matsuzaki, Susan Ceryak, Maryam Al Rashid, Bernard Bouscarel, Tadashi Ikegami
Publikováno v:
Molecular Cancer Therapeutics. 5:68-79
Certain hydrophobic bile acids, including deoxycholic acid and chenodeoxycholic acid, exert toxic effects not only in the liver but also in the intestine. Moreover, ursodeoxycholic acid (UDCA), which has protective actions against apoptosis in the li
Autor:
Masaaki Karube, Naomi Tanaka, Tadashi Ikegami, Teruo Miyazaki, Mikio Doy, Bernard Bouscarel, Yasushi Matsuzaki
Publikováno v:
Journal of Hepatology. 43:117-125
Background/Aims The aim of the study was to examine the effects of taurine on hepatic fibrogenesis and in isolated hepatic stellate cells (HSC). Methods The rats of the hepatic damage (HD) group were administered carbon tetracholoride (CCl 4 ) for 5
Autor:
Naomi Tanaka, Yasushi Matsuzaki, Teruo Miyazaki, Mikio Doy, Tadashi Ikegami, Bernard Bouscarel, Shumpei Miyakawa
Publikováno v:
Journal of Gastroenterology. 39:557-562
We have previously reported that oral taurine administration reduced the frequency of painful muscle cramps in patients with liver cirrhosis, and that skeletal muscle taurine concentration was significantly decreased after exercise. The aim of this s
Autor:
Naomi Tanaka, Teruo Miyazaki, Norio Ohkoshi, Shunpei Miyakawa, Bernard Bouscarel, Yasushi Matsuzaki
Publikováno v:
Hepatology Research. 24:368-378
It is well known that painful muscle cramps occur frequently in patients with advanced liver cirrhosis (LC). Although many studies discuss the pathophysiological causes of these muscle cramps in various conditions, the results are not clear as far as
Autor:
Naomi Tanaka, Tadashi Ikegami, Teruo Miyazaki, Bernard Bouscarel, Yasushi Matsuzaki, Syunpei Miyakawa
Publikováno v:
Medicine & Science in Sports & Exercise. 34:793-797
MATSUZAKI, Y., T. MIYAZAKI, S. MIYAKAWA, B. BOUSCAREL, T. IKEGAMI, and N. TANAKA. Decreased taurine concentration in skeletal muscles after exercise for various durations. Med. Sci. Sports Exerc., Vol. 34, No. 5, pp. 793–797, 2002. Purpose: To exam