Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bernard Appeltans"'
Autor:
Karyna Krupianskaya, Bart Croonenborghs, Annick Gillet, Bernard Appeltans, Anke Meyers, Aaron DeMent, Guy Van den Mooter, Ann Van Schepdael, Erik Haghedooren
Sterilization is a pivotal topic in the pharmaceutical industry, whereby the nomenclature of “sterile” refers to the absence of viable microorganisms. Since microorganisms can reproduce in the body and cause potentially fatal infections, it is cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b66ac2c358f23ff154a4ed686af362
https://lirias.kuleuven.be/handle/20.500.12942/712347
https://lirias.kuleuven.be/handle/20.500.12942/712347
Publikováno v:
International Journal of Pharmaceutics. 609:121201
In spite of the fact that spray drying is widely applied for the formulation of amorphous solid dispersions (ASDs), the influence of the solvent on the physical properties of the ASDs is still not completely understood. Therefore, the impact of organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244f1811be27ecd149aaa99153906180
https://doi.org/10.1016/j.ijpharm.2021.121201
https://doi.org/10.1016/j.ijpharm.2021.121201
Autor:
Alexander Y. Sitenkov, A. V. Bukhovets, Guy Van den Mooter, Tatiana V. Kabanova, Shamil F. Nasibullin, Bernard Appeltans, Rouslan I. Moustafine, Vitaliy V. Khutoryanskiy
Publikováno v:
International Journal of Pharmaceutics. 524:121-133
Potential applications of a novel system composed of two oppositely-charged (meth)acrylate copolymers, Eudragit® ЕРО (EPO) and Eudragit® S100 (S100), loaded with indomethacin (IND) in oral drug delivery were evaluated. The particles based on dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb8deee335bcf0537aa549a634b8c13
https://doi.org/10.1016/j.ijpharm.2017.03.053
https://doi.org/10.1016/j.ijpharm.2017.03.053
Publikováno v:
International journal of pharmaceutics. 573
Solid dosage forms of amorphous solid dispersions (ASDs) have rarely been assessed for their crushability, although it might possibly be a more frequent practice than thought to facilitate oral administration in several clinical conditions (e.g. dysp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3763c6ba1694221cf923a06f1cecb78e
https://pubmed.ncbi.nlm.nih.gov/31786356
https://pubmed.ncbi.nlm.nih.gov/31786356
Autor:
Manoela Klüppel Riekes, Bernard Appeltans, Hellen Karine Stulzer, Patrick Rombaut, Axel Engelen, Guy Van den Mooter
Publikováno v:
Pharmaceutical Research. 33:1259-1275
PURPOSE: Aiming to improve the dissolution rate of ezetimibe (EZE) and lovastatin (LOV) in a fixed dose combination (FDC), co-amorphous systems and ternary solid dispersions were prepared by quench cooling and spray drying, respectively. METHODS: For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9d9914c858cf077c3b5fc99909d78b
https://doi.org/10.1007/s11095-016-1870-z
https://doi.org/10.1007/s11095-016-1870-z
Autor:
Uwe Himmelreich, Sayuan Liang, Bernard Appeltans, Greetje Vande Velde, Guy Van den Mooter, Dominiek Staelens, Marlies Van de Wouwer, Gert Van Assche
Publikováno v:
Contrast Media & Molecular Imaging. 11:24-31
Delayed controlled release is an innovative strategy to locally administer therapeutic compounds (e.g. chemotherapeutics, antibodies etc.). This would improve efficiency and reduce side effects compared with systemic administration. To enable the eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edc869a405b7879b30d42f33bd089d2
https://doi.org/10.1002/cmmi.1654
https://doi.org/10.1002/cmmi.1654
Autor:
Joke Meeus, Bernard Appeltans, David J. Scurr, Guy Van den Mooter, Pieter Annaert, Martyn C. Davies, Katie Amssoms, Clive J. Roberts
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 90:22-29
Understanding and controlling the in vitro release behavior of a formulation is a first step toward rationalized selection of a solubility enhancing formulation strategy with a desired release profile in vivo. Therefore six model formulations, repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26084521eba463989a3f23ef917a85b3
https://doi.org/10.1016/j.ejpb.2014.11.009
https://doi.org/10.1016/j.ejpb.2014.11.009
Autor:
Rouslan I, Moustafine, Alexander Y, Sitenkov, Alexandra V, Bukhovets, Shamil F, Nasibullin, Bernard, Appeltans, Tatiana V, Kabanova, Vitaliy V, Khutoryanskiy, Guy, Van den Mooter
Publikováno v:
International journal of pharmaceutics. 524(1-2)
Potential applications of a novel system composed of two oppositely-charged (meth)acrylate copolymers, Eudragit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82e76dc4ff3e969fe45d09442dd6edfd
https://pubmed.ncbi.nlm.nih.gov/28366803
https://pubmed.ncbi.nlm.nih.gov/28366803
Autor:
Bernard Appeltans, Patrick Augustijns, Tania Crucitti, Kevin K. Ariën, Johan Michiels, Carolien Grammen, Koen Augustyns, Guy Van den Mooter, Joachim Brouwers
Publikováno v:
International journal of pharmaceutics
The purpose of this work was to design and evaluate a vaginal film delivery system for UAMC01398, a novel non-nucleoside reverse transcriptase inhibitor currently under investigation for use as an anti-HIV microbicide. UAMC01398 (1 mg) films consisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535e17a0e5f5a737914c422561d9d64f
https://doi.org/10.1016/j.ijpharm.2014.08.054
https://doi.org/10.1016/j.ijpharm.2014.08.054
Autor:
Dominiek, Staelens, Sayuan, Liang, Bernard, Appeltans, Marlies, Van de Wouwer, Guy, Van den Mooter, Gert, Van Assche, Uwe, Himmelreich, Greetje, Vande Velde
Publikováno v:
Contrast mediamolecular imaging. 11(1)
Delayed controlled release is an innovative strategy to locally administer therapeutic compounds (e.g. chemotherapeutics, antibodies etc.). This would improve efficiency and reduce side effects compared with systemic administration. To enable the eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da864c57ac29088ef6535eeefdac0cc2
https://pubmed.ncbi.nlm.nih.gov/26190202
https://pubmed.ncbi.nlm.nih.gov/26190202