Výsledky vyhledávání - "Bernard Pucci"

Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles

Autor: Frances M. Ashcroft, Ange Polidori, Constantina Fotinou, Jussi Aittoniemi, Heidi de Wet, Mark S.P. Sansom, Catherine Vénien-Bryan, Bernard Pucci

Publikováno v: The Febs Journal
FEBS Journal
FEBS Journal, Wiley, 2013, 280 (4), pp.1051-63. ⟨10.1111/febs.12097⟩
FEBS Journal, Wiley, 2013, ⟨10.1111/febs.12097⟩
FEBS Journal, 2013, 280 (4), pp.1051-63. ⟨10.1111/febs.12097⟩

International audience; The ATP-sensitive potassium (K ATP) channel is a hetero-octameric complex that links cell metabolism to membrane electrical activity in many cells, thereby controlling physiological functions such as insulin release, muscle co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd71a687a9c6c7367cc6e6a30ac627f
http://europepmc.org/articles/PMC3599479

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Folding of diphtheria toxin T-domain in the presence of amphipols and fluorinated surfactants: Toward thermodynamic measurements of membrane protein folding

Autor: Mauricio Vargas-Uribe, Alexander Kyrychenko, Alexey S. Ladokhin, Shivaji K. Sharma, Mykola V. Rodnin, Jean-Luc Popot, Grégory Durand, Bernard Pucci

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2012, ⟨10.1016/j.bbamem.2011.09.012⟩
Biochimica biophysica acta (BBA)-Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2012, ⟨10.1016/j.bbamem.2011.09.012⟩

International audience; Solubilizing membrane proteins for functional, structural and thermodynamic studies is usually achieved with the help of detergents, which, however, tend to destabilize them. Several classes of non-detergent sur-factants have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75488296c9baf2ac417c7dffc8234b47

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Production of UCP1 a membrane protein from the inner mitochondrial membrane using the cell free expression system in the presence of a fluorinated surfactant

Autor: L.-A Barret, Ange Polidori, Manuela Zoonens, Stéphanie Ravaud, Céline Juillan-Binard, Eva Pebay-Peyroula, Bruno Miroux, Iulia Blesneac, Bernard Pucci

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, 2012, 1818 (3), pp.798-805. ⟨10.1016/j.bbamem.2011.12.016⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2012, 1818 (3), pp.798-805. ⟨10.1016/j.bbamem.2011.12.016⟩

International audience; Structural studies of membrane protein are still challenging due to several severe bottlenecks, the first being the overproduction of well-folded proteins. Several expression systems are often explored in parallel to fulfil th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74239bbda3d34c8c5d8f6062f1aa672d

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Non-Ionic Amphiphilic Homopolymers: Synthesis, Solution Properties, and Biochemical Validation

Autor: Emmanuelle Billon-Denis, Jean-Luc Popot, Christel Le Bon, K. Shivaji Sharma, Christine Ebel, Frank Gabel, Grégory Durand, Laurent Catoire, Paola Bazzacco, Bernard Pucci

Publikováno v: Langmuir
Langmuir, American Chemical Society, 2012, ⟨10.1021/la205026r⟩
Langmuir, 2012, ⟨10.1021/la205026r⟩

International audience; A novel type of nonionic amphipols for handling membrane proteins in detergent-free aqueous solutions has been obtained through free-radical homo-telomerization of an acrylamide-based monomer comprising a C 11 alkyl chain and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b744a9b164db719a699681da5f9c6e7d
https://doi.org/10.1021/la205026r

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Synthesis and Determination of Polymerization Rate Constants of Glucose-Based Monomers

Autor: Grégory Durand, Bernard Pucci, Shivaji K. Sharma

Publikováno v: Designed Monomers and Polymers. 14:499-513

To prepare non-ionic amphiphilic polymers usable for solubilizing integral membrane proteins, hydrophilic and amphiphilic β-D-glucose-based tris(hydroxymethyl)acrylamidomethane monomers were synthesized and their radical homopolymerization rate cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cc35fe4f649bdaebfde40891ada0d65
https://doi.org/10.1163/138577211x587690

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Cholesterol-based α-phenyl-N-tert-butyl nitrone derivatives as antioxidants against light-induced retinal degeneration

Autor: Grégory Durand, Isabelle Ranchon-Cole, Fanny Choteau, C. Cercy, Bernard Pucci

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 20:7405-7409

Two cholesterol-based α-phenyl-N-tert-butyl nitrone derivatives were synthesized as antioxidants against light-induced retinal degeneration. Whereas nitrone 10 significantly protected retina against bright fluorescent light exposure when injected in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27892deec04b3bcfbb9d34f91c1b188e
https://doi.org/10.1016/j.bmcl.2010.10.037

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Stability study of the human G-protein coupled receptor, Smoothened

Autor: Bernard Pucci, Michel Bidet, Isabelle Mus-Veteau, Ange Polidori, Olivier Joubert, Benoît Lacombe, Rony Nehmé

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2010, 1798 (6), pp.1100-10. ⟨10.1016/j.bbamem.2010.02.015⟩

International audience; Smoothened is a member of the G-protein coupled receptor (GPCR) family responsible for the transduction of the Hedgehog signal to the intracellular effectors of the Hedgehog signaling pathway. Aberrant regulation of this recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a12b3ec4296e7465a7159df192ac71

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Trapping and Stabilization of Integral Membrane Proteins by Hydrophobically Grafted Glucose-Based Telomers

Autor: Christine Ebel, Paola Bazzacco, Jean-Luc Popot, K. Shivaji Sharma, Bernard Pucci, Fabrice Giusti, Grégory Durand

Publikováno v: Biomacromolecules
Biomacromolecules, 2009, 10 (12), pp.3317-3326. ⟨10.1021/bm900938w⟩
Biomacromolecules, American Chemical Society, 2009, 10 (12), pp.3317-3326. ⟨10.1021/bm900938w⟩

Amphipols (APols) are short amphipathic polymers designed to adsorb onto the transmembrane surface of membrane proteins, keeping them water-soluble in the absence of detergent. Current APols carry charged groups, which is a limitation for certain typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1991567a1470735b7de520ccbf2e6636
https://doi.org/10.1021/bm900938w

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Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging

Autor: A. Belland, Audrey Parat, Bernard Pucci, Michel Bessodes, P. Chaumet-Riffaud, Christiane Contino-Pépin, Nathalie Mignet, Daniel Scherman, Cyrille Richard

Publikováno v: International Journal of Pharmaceutics. 379:301-308

The synthesis of three molecules containing a fluorocarbon chain (either C(6)F(13), C(8)F(17) or C(10)F(21)), a sugar moiety (derived from lactobionic acid) and a chelate (derived from DTPA) is reported. These molecules (C(6)F(13)-Gal-DTPA, C(8)F(17)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f9631d0fbd0a4830f4beb99234521e
https://doi.org/10.1016/j.ijpharm.2009.05.045

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