Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Bernard Knoops"'
Autor:
Celien Lismont, Iulia Revenco, Hongli Li, Cláudio F. Costa, Lisa Lenaerts, Mohamed A. F. Hussein, Jonas De Bie, Bernard Knoops, Paul P. Van Veldhoven, Rita Derua, Marc Fransen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The involvement of peroxisomes in cellular hydrogen peroxide (H2O2) metabolism has been a central theme since their first biochemical characterization by Christian de Duve in 1965. While the role of H2O2 substantially changed from an exclusively toxi
Externí odkaz:
https://doaj.org/article/58e2b8a6b90f4af5999c1dcd7f8fb8b3
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Peroxiredoxins are ubiquitous thiol-dependent peroxidases that represent a major antioxidant defense in both prokaryotic cells and eukaryotic organisms. Among the six vertebrate peroxiredoxin isoforms, peroxiredoxin-5 (PRDX5) appe
Externí odkaz:
https://doaj.org/article/b2f96ddc3bd24d2ba75488e2aaf102cc
Autor:
Mégane A. Poncin, Pierre Van Meerbeeck, Joshua D. Simpson, André Clippe, François Tyckaert, Fabrice Bouillenne, Hervé Degand, André Matagne, Pierre Morsomme, Bernard Knoops, David Alsteens
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1902 (2021)
Human peroxiredoxin-5 (PRDX5) is a unique redox-sensitive protein that plays a dual role in brain ischemia-reperfusion injury. While intracellular PRDX5 has been reported to act as a neuroprotective antioxidative enzyme by scavenging peroxides, once
Externí odkaz:
https://doaj.org/article/486e8150528c4f38ad31f2c78e3150f9
Publikováno v:
International Journal of Obesity. 46:1311-1318
Glucagon-like peptide-1 receptor agonists (GLP-1ra) are increasingly used in treating type 2 diabetes and obesity. Exendin-4 (Ex-4), a long acting GLP-1ra, was previously reported to decrease oxidative stress in hepatocytes, adipocytes and skeletal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a45f0a4a9470c3a3112ffb79d91955f
https://doi.org/10.1038/s41366-022-01114-2
https://doi.org/10.1038/s41366-022-01114-2
Autor:
M. Fransen, Liesbeth Lenaerts, J. De Bie, P. P. Van Veldhoven, Celien Lismont, M. Hussein, C. Costa, Bernard Knoops, Rita Derua, Iulia Revenco, H. Li
Ever since the first characterization of peroxisomes, a central theme has been their involvement in cellular hydrogen peroxide (H2O2) metabolism. While the reputation of H2O2 drastically changed from an exclusively toxic molecule to a signaling messe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef46fdf76f673b6761c2d7ba290afbe6
https://doi.org/10.1101/2021.10.08.463647
https://doi.org/10.1101/2021.10.08.463647
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142280 (2015)
Thioredoxin-2 (Trx2) is a mitochondrial protein using a dithiol active site to reduce protein disulfides. In addition to the cytoprotective function of this enzyme, several studies have highlighted the implication of Trx2 in cellular signaling events
Externí odkaz:
https://doaj.org/article/1088819dac4f4eea9766e9c3c4922e55
Autor:
Valérie Van der Eecken, André Clippe, Sophie Dekoninck, Julie Goemaere, Geoffroy Walbrecq, Paul P Van Veldhoven, Bernard Knoops
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72844 (2013)
In human, the subcellular targeting of peroxiredoxin-5 (PRDX5), a thioredoxin peroxidase, is dependent on the use of multiple alternative transcription start sites and two alternative in-frame translation initiation sites, which determine whether or
Externí odkaz:
https://doaj.org/article/9f52ae0204ed4aeda6bfb531b3e1eccb
Autor:
Sarah Barelier, Dominique Linard, Julien Pons, André Clippe, Bernard Knoops, Jean-Marc Lancelin, Isabelle Krimm
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9744 (2010)
The search for protein ligands is a crucial step in the inhibitor design process. Fragment screening represents an interesting method to rapidly find lead molecules, as it enables the exploration of a larger portion of the chemical space with a small
Externí odkaz:
https://doaj.org/article/499a58ea816d4ef1a2622b029f23831b
Autor:
Bernard Knoops, Mégane A. Poncin, Pierre Morsomme, David Alsteens, Joshua D. Simpson, André Clippe, Pierre Van Meerbeeck, Fabrice Bouillenne, André Matagne, Hervé Degand, François Tyckaert
Publikováno v:
Antioxidants; Volume 10; Issue 12; Pages: 1902
Antioxidants
Antioxidants, Vol 10, Iss 1902, p 1902 (2021)
Antioxidants, Vol. 10, no.12, p. 1902 (2021)
Antioxidants
Antioxidants, Vol 10, Iss 1902, p 1902 (2021)
Antioxidants, Vol. 10, no.12, p. 1902 (2021)
Human peroxiredoxin-5 (PRDX5) is a unique redox-sensitive protein that plays a dual role in brain ischemia-reperfusion injury. While intracellular PRDX5 has been reported to act as a neuroprotective antioxidative enzyme by scavenging peroxides, once
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb610f2347eb355f66339584a9111bf9
https://doi.org/10.3390/antiox10121902
https://doi.org/10.3390/antiox10121902
Autor:
Eric Mignolet, Géraldine Cuvelier, Melissa M. Page, Emeline Dierge, Bernard Knoops, Perrine Vermonden, Yvan Larondelle, Cathy Debier, Matthias Vancoppenolle, Olivier Feron
Publikováno v:
Nutrients
Volume 13
Issue 8
Nutrients, Vol 13, Iss 2751, p 2751 (2021)
Nutrients, Vol. 13, no. 8, p. 2751 [1-16] (2021)
Volume 13
Issue 8
Nutrients, Vol 13, Iss 2751, p 2751 (2021)
Nutrients, Vol. 13, no. 8, p. 2751 [1-16] (2021)
Plant-derived conjugated linolenic acids (CLnA) have been widely studied for their preventive and therapeutic properties against diverse diseases such as cancer. In particular, punicic acid (PunA), a conjugated linolenic acid isomer (C18:3 c9t11c13)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bfbec18e09f49af19c16e82a34a5bd
https://doi.org/10.3390/nu13082751
https://doi.org/10.3390/nu13082751