Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Bernard, de Bono"'
Autor:
John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Sherry L. Jenkins, Taha Mohseni Ahooyi, Cristian G. Bologa, Jeremy J. Yang, Jessica L. Binder, Praveen Kumar, Christophe G. Lambert, Jeffrey S. Grethe, Eric Wenger, Deanne Taylor, Tudor I. Oprea, Bernard de Bono, Avi Ma’ayan
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Abstract Background Birth defects are functional and structural abnormalities that impact about 1 in 33 births in the United States. They have been attributed to genetic and other factors such as drugs, cosmetics, food, and environmental pollutants d
Externí odkaz:
https://doaj.org/article/3b529ae9cc3f41ad82da2371efbd1a29
Autor:
Monique C. Surles-Zeigler, Troy Sincomb, Thomas H. Gillespie, Bernard de Bono, Jacqueline Bresnahan, Gary M. Mawe, Jeffrey S. Grethe, Susan Tappan, Maci Heal, Maryann E. Martone
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
The stimulating peripheral activity to relieve conditions (SPARC) program is a US National Institutes of Health-funded effort to improve our understanding of the neural circuitry of the autonomic nervous system (ANS) in support of bioelectronic medic
Externí odkaz:
https://doaj.org/article/59648cb456864ca2a1540a10916cd0c3
Autor:
Bernard de Bono, Tom Gillespie, Monique C. Surles-Zeigler, Natallia Kokash, Jeff S. Grethe, Maryann Martone
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
We present (i) the ApiNATOMY workflow to build knowledge models of biological connectivity, as well as (ii) the ApiNATOMY TOO map, a topological scaffold to organize and visually inspect these connectivity models in the context of a canonical archite
Externí odkaz:
https://doaj.org/article/e3bd2d553977463d8ab6c25bdaf19d8f
Autor:
Dewan M. Sarwar, Reza Kalbasi, John H. Gennari, Brian E. Carlson, Maxwell L. Neal, Bernard de Bono, Koray Atalag, Peter J. Hunter, David P. Nickerson
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Mathematics and Phy sics-based simulation models have the potential to help interpret and encapsulate biological phenomena in a computable and reproducible form. Similarly, comprehensive descriptions of such models help to ensure
Externí odkaz:
https://doaj.org/article/88988399891345fb876823d486557f18
Autor:
Mahyar Osanlouy, Anita Bandrowski, Bernard de Bono, David Brooks, Antonino M. Cassarà, Richard Christie, Nazanin Ebrahimi, Tom Gillespie, Jeffrey S. Grethe, Leonardo A. Guercio, Maci Heal, Mabelle Lin, Niels Kuster, Maryann E. Martone, Esra Neufeld, David P. Nickerson, Elias G. Soltani, Susan Tappan, Joost B. Wagenaar, Katie Zhuang, Peter J. Hunter
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The Data and Resource Center (DRC) of the NIH-funded SPARC program is developing databases, connectivity maps, and simulation tools for the mammalian autonomic nervous system. The experimental data and mathematical models supplied to the DRC by the S
Externí odkaz:
https://doaj.org/article/71c1ff663c464de39d8e73e6e0a64353
Autor:
Natallia Kokash, Bernard de Bono
Publikováno v:
Frontiers in Neuroinformatics, Vol 15 (2021)
We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of A
Externí odkaz:
https://doaj.org/article/177c2ec1ea9743c5986a94914d2a856e
Autor:
David Nickerson, David Brooks, Biruthuvan Balachandran, Tom Gillespie, Fahim Imam, Jeffrey Grethe, Susan Tappan, Bernard de Bono, Maryann Martone, Peter Hunter
Publikováno v:
Physiology. 38
The December 2022 release of the SPARC Portal ( https://sparc.science ) included the first significant update to the anatomical connectivity flatmaps since the portal first launched. These flatmaps provide an interactive and visual map for the displa
Autor:
John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Taha M. Ahooyi, Sherry L. Jenkins, Deanne Taylor, Cristian G. Bologa, Jeremy J. Yang, Jessica L. Binder, Praveen Kumar, Christophe G. Lambert, Jeffrey S. Grethe, Eric Wenger, Tudor I. Oprea, Bernard de Bono, Avi Ma’ayan
Birth defects are functional and structural abnormalities that impact 1 in 33 births in the United States. Birth defects have been attributed to genetic as well as other factors, but for most birth defects there are no known causes. Small molecule dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fcaf7345434da03c63ea9da88c526f
https://doi.org/10.1101/2022.09.15.508198
https://doi.org/10.1101/2022.09.15.508198
Autor:
Jacqueline C. Bresnahan, Monique C Surles-Zeigler, Maryann E. Martone, Jeffrey S. Grethe, Bernard de Bono, Maci Heal, Susan Tappan, Troy Sincomb, Tom Gillespie, Gary M. Mawe
The Stimulating Peripheral Activity to Relieve Conditions (SPARC) program is a US National Institutes of Health-funded effort to improve our understanding of the neural circuitry of the autonomic nervous system in support of bioelectronic medicine. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea72538d0ad2a33b4859e6ee522a62b
https://doi.org/10.1101/2021.11.15.467961
https://doi.org/10.1101/2021.11.15.467961
Autor:
G, Stamatakos, Dimitra, Dionysiou, Fay, Misichroni, Norbert, Graf, Stefaan, van Gool, Rainar, Bohle, Feng, Dong, Marco, Viceconti, Kostas, Marias, Vangelis, Sakkalis, Nikolaus, Forgo, Ravi, Radhakrishnan, Helen, Byrne, Caterina, Guiot, Philippe, Buechler, Elias, Neri, Anca, Bucur, Bernard, de Bono, Debora, Testi, Manolis, Tsiknakis
Publikováno v:
Proc 2014 6th Int Adv Res Workshop In Silico Oncol Cancer Investig (2014)
This paper briefly outlines the aim, the objectives, the architecture and the main building blocks of the ongoing large scale integrating transatlantic research project CHIC (http://chic-vph.eu/).