Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bernard, Verdon"'
Autor:
Catherine F. Hatton, Rachel A. Botting, Maria Emilia Dueñas, Iram J. Haq, Bernard Verdon, Benjamin J. Thompson, Jarmila Stremenova Spegarova, Florian Gothe, Emily Stephenson, Aaron I. Gardner, Sandra Murphy, Jonathan Scott, James P. Garnett, Sean Carrie, Jason Powell, C. M. Anjam Khan, Lei Huang, Rafiqul Hussain, Jonathan Coxhead, Tracey Davey, A. John Simpson, Muzlifah Haniffa, Sophie Hambleton, Malcolm Brodlie, Chris Ward, Matthias Trost, Gary Reynolds, Christopher J. A. Duncan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The innate immune response in epithelial cells after SARS-CoV-2 infection is not fully understood. Here the authors use human air-liquid interface culture and show single cell transcription changes and delayed type I Interferon responses after SARS-C
Externí odkaz:
https://doaj.org/article/0c29a923bed447a88b3b4df91dd15100
Autor:
Michael William Mather, Bernard Verdon, Rachel Anne Botting, Justin Engelbert, Livia Delpiano, Xin Xu, Catherine Hatton, Tracey Davey, Steven Lisgo, Philip Yates, Nicholas Dawe, Colin D. Bingle, Muzlifah Haniffa, Jason Powell, Chris Ward
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1167-1174 (2021)
Abstract Introduction Otitis media is an umbrella term for middle ear inflammation; ranging from acute infection to chronic mucosal disease. It is a leading cause of antimicrobial therapy prescriptions and surgery in children. Despite this, treatment
Externí odkaz:
https://doaj.org/article/eedd5c1112b44d41b04eeb3fcdf4bffe
Publikováno v:
ERJ Open Research, Vol 3, Iss 1 (2017)
Gastro-oesophageal reflux and aspiration have been associated with chronic and end-stage lung disease and with allograft injury following lung transplantation. This raises the possibility that bile acids may cause lung injury by damaging airway epith
Externí odkaz:
https://doaj.org/article/291c4d1dcf3d4680a4d85acee16e1a32
Autor:
Robert M Jackson, Catherine F Hatton, Jarmila Stremenova Spegarova, Maria Georgiou, Joseph Collin, Emily Stephenson, Bernard Verdon, Iram J Haq, Rafiqul Hussain, Jonathan M Coxhead, Hardeep-Singh Mudhar, Bart Wagner, Megan Hasoon, Tracey Davey, Paul Rooney, C.M. Anjam Khan, Chris Ward, Malcolm Brodlie, Muzlifah Haniffa, Sophie Hambleton, Lyle Armstrong, Francisco Figueiredo, Rachel Queen, Christopher J A Duncan, Majlinda Lako
Publikováno v:
Stem cell reports. 17(7)
Although tropism of SARS-CoV-2 for respiratory tract epithelial cells is well established, an open question is whether the conjunctival epithelium is also a target for SARS-CoV-2. Conjunctival epithelial cells, which express viral entry receptors ACE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab674592947260fe7f29d2d14beff1d
https://pubmed.ncbi.nlm.nih.gov/35750043
https://pubmed.ncbi.nlm.nih.gov/35750043
Autor:
Rachel A. Botting, Bernard Verdon, Jason Powell, Michael W. Mather, Tracey Davey, Steven Lisgo, Nicholas Dawe, Muzlifah Haniffa, Catherine F Hatton, Livia Delpiano, Justin Engelbert, Philip Yates, Chris Ward, Colin D. Bingle, Xin Xu
Publikováno v:
Laryngoscope Investigative Otolaryngology
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1167-1174 (2021)
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1167-1174 (2021)
Introduction\ud \ud Otitis media is an umbrella term for middle ear inflammation; ranging from acute infection to chronic mucosal disease. It is a leading cause of antimicrobial therapy prescriptions and surgery in children. Despite this, treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8771d94a2c379b0187c290e8bc3bb2
Autor:
Jason Powell, Sandra Murphy, Emily Stephenson, Benjamin J. Thompson, Jonathan M. Scott, Maria Emilia Dueñas, Muzlifah Haniffa, Sophie Hambleton, Chris Ward, Jonathan Coxhead, Gary Reynolds, James P. Garnett, Rafiqul Hussain, Aaron Gardner, Anjam C M Khan, John Simpson, Malcolm Brodlie, Matthias Trost, Tracey Davey, Iram J. Haq, Jarmila Stremenova Spegarova, Lei Huang, Christopher J A Duncan, Sean Carrie, Catherine F Hatton, Bernard Verdon, Florian Gothe, Rachel A. Botting
The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) responses are critical to outcome of SARS-CoV-2. Yet little is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd82c2156fed1bb54bfe6ba438a81ee3
https://doi.org/10.1101/2021.02.17.431591
https://doi.org/10.1101/2021.02.17.431591
Autor:
Vinciane Saint-Criq, Alexandra Trigg, John P. Clancy, Malcolm Brodlie, Andrew J. Fisher, A. John Simpson, John Gallagher, Michael A. Gray, Albert Koulman, Emily Mavin, Elizabeth L. Kramer, Melissa J. McDonnell, Aaron Gardner, Edward H. Schuchman, Bernard Verdon, Chris Ward, Iram J. Haq, Erich Gulbins, Katrin Anne Becker
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2020, 202 (8), pp.1133-1145. ⟨10.1164/rccm.202001-0180OC⟩
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2020, 202 (8), pp.1133-1145. ⟨10.1164/rccm.202001-0180OC⟩
Rationale: In cystic fibrosis the major cause of morbidity and mortality is lung disease characterized by inflammation and infection. The influence of sphingolipid metabolism is poorly understood with a lack of studies using human airway model system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a429fa07d67e18e622f522597e7c3c3
https://hal.inrae.fr/hal-02977354
https://hal.inrae.fr/hal-02977354
Autor:
Sean Carrie, Christian A. Kuttruff, Chris Ward, Satomi Miwa, James P. Garnett, Jason Powell, Emily Mavin, Vinciane Saint-Criq, Bernard Verdon
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2020, 318 (6), pp.L1158-L1164. ⟨10.1152/ajplung.00414.2019⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2020, 318 (6), pp.L1158-L1164. ⟨10.1152/ajplung.00414.2019⟩
Shifts in cellular metabolic phenotypes have the potential to cause disease-driving processes in respiratory disease. The respiratory epithelium is particularly susceptible to metabolic shifts in disease, but our understanding of these processes is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c84bbbc1abe2b08abc17a916faa8adc
https://hal.inrae.fr/hal-02977357
https://hal.inrae.fr/hal-02977357
Autor:
Lee A Borthwick, Phil Botha, Bernard Verdon, Malcolm J Brodlie, Aaron Gardner, David Bourn, Gail E Johnson, Mike A Gray, Andrew J Fisher
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23226 (2011)
Understanding where mutant CFTR is localised in airway epithelia is essential in guiding the best therapeutic approach to correct the dysfunction of the CFTR protein. The widely held paradigm is that CF patients harbouring the commonest mutation, CFT
Externí odkaz:
https://doaj.org/article/b7a8b299ab8547b6aadfb442d0b5e3b7
Autor:
Bernard Verdon, Michael W. Mather, Vinidh Paleri, Chris Ward, Janet A. Wilson, Zachary Shellman, Adil Aldhahrani, Jason Powell, Jeffrey P. Pearson
Publikováno v:
Clinical Otolaryngology. 42:969-973
Objective Gastro-oesophageal reflux disease is thought to be a risk factor for head and neck malignancies. Bile acids are one of the principle components of gastric refluxate and have previously been implicated in the development of oesophageal and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb2cced6807a93a129eafd39e0dee24
https://doi.org/10.1111/coa.12822
https://doi.org/10.1111/coa.12822