Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Bernard, Scatton"'
Autor:
Hubert H. M. Van Tol, Pierre F. Spano, Pierre Sokoloff, David R. Sibley, Philip Seeman, Goran Sedvall, Jean-Charles Schwartz, Bernard Scatton, Kim A. Neve, Maria Cristina Missale, Saloman Z. Langer, John W. Kebabian, David K. Grandy, Raul R. Gainetdinov, Gilberto Fisone, Stefano Espinoza, Olivier Civelli, Marc G. Caron, Arvid Carlsson, Emiliana Borrelli, Jean-Martin Beaulieu
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [373]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is dopamine.
Publikováno v:
Journal of Neurochemistry. 158:818-820
This is an obituary of Dr. Jacques Glowinski (1936-2020), one of the last « giants » of Neuropharmacology trained in the sixties in the laboratory of Julius Axelrod (Nobel Prize in 1970). He was a founding father of this discipline in France and hi
Autor:
Hubert H.M. Van Tol, David R. Sibley, Jean-Charles Schwartz, Saloman Z. Langer, Kim A. Neve, John W. Kebabian, Jean-Martin Beaulieu, Arvid Carlsson, Marc G. Caron, Pierre Sokoloff, Pierre F. Spano, Olivier Civelli, Emiliana Borrelli, Maria Cristina Missale, Philip Seeman, Bernard Scatton, Raul R. Gainetdinov, Gilberto Fisone, Göran Sedvall, Stefano Espinoza, David K. Grandy
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [363]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is dopamine.
Autor:
Jean-Michel Stutzmann, Bernard Scatton
Publikováno v:
Epilepsies. 21:264-267
Auteur(s) : Bernard Scatton1,2, Jean-Michel Stutzmann1,2 1Departement de recherche Amont, Sanofi-Aventis R&D, 31, avenue Paul-Vaillant-Couturier, 92220 Bagneux (BS), France 2Departement de recherche Amont, Sanofi-Aventis R&D, 13, quai Jules-Guesde, 9
Autor:
Bernard Scatton
Publikováno v:
Journal de la Société de Biologie. 203:249-269
This paper reviews the process used in the pharmaceutical industry to discover new innovative drugs originating from medicinal chemistry or biotherapeutics. After a rapid description of the global Research and Development process (preclinical and cli
Autor:
Bruno Biton, Guy Griebel, Caroline Cohen, Pascal George, Philippe Pichat, Mireille Sevrin, Genevieve Estenne-Bouhtou, Nancy Rogacki, C. Desvignes, Bernard Scatton, Patrick Avenet, Xavier Vigé, Jeanne Stemmelin, Olivier Bergis, Annick Coste, Denis Boulay, Christophe Lanneau, Jean Paul Terranova, Régis Steinberg, R. Alonso, Gihad Dargazanli, F. Oury-Donat
Publikováno v:
Pharmacology Biochemistry and Behavior. 91:47-58
On native human, rat and mouse glycine transporter-1(GlyT1), SSR130800 behaves as a selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked glycine uptake in mouse brain cortical homogenates, increased extrace
Autor:
Mathieu Desbazeille, Pascal Ludwiczak, Bernard Scatton, Frédéric Béquet, Claudine Picard, Mohamed Maftouh, Françoise Uzabiaga, Gérard Le Fur
Publikováno v:
European Journal of Neuroscience. 26:3458-3464
In the present study, we examined the occurrence and potential regulation of endocannabinoid release by cannabinoid CB1 receptors in the rat brain. To this end, we developed a highly sensitive (limit of sensitivity 30-300 amol) new analytical method,
Autor:
R. Alonso, Guy Griebel, Bernard Scatton, Patrick Avenet, Dominique Françon, Gérard Le Fur, Olivier Bergis, Jeanne Stemmelin, Vincent Santucci, Matilde Lopez-Grancha, Caroline Cohen, Michel Decobert, Philippe Pichat, Terranova Jean-Paul, P.E. Keane, Stephen M. Stahl
Publikováno v:
Neuropsychopharmacology. 33:574-587
The characterization of the first selective orally active and brain-penetrant beta3-adrenoceptor agonist, SR58611A (amibegron), has opened new possibilities for exploring the involvement of this receptor in stress-related disorders. By using a batter
Publikováno v:
Journal of Neurochemistry. 46:1794-1801
The release of endogenous noradrenaline was measured in the cerebral cortex of the halothane-anesthetized rat by using the technique of brain dialysis coupled to a radioenzymatic assay. A thin dialysis tube was inserted transversally in the cerebral