Výsledky vyhledávání - "Bernard, Mariamé"

Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

Autor: Franck, Gallardo, Bernard, Mariamé, Remi, Gence, Anne-Francoise, Tilkin-Mariamé

Publikováno v: Drug design, development and therapy. 12

The Epstein-Barr virus (EBV)-associated cancer nasopharyngeal carcinoma (NPC) is rare in Europe and North America but is a real public health problem in some regions of the world, such as southern Asia, North Africa, and for Inuit populations. Due to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ede8301d595f5301f0eb40ee98ecd44d
https://pubmed.ncbi.nlm.nih.gov/30233143

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Real-Time Visualization and Quantification of Human Cytomegalovirus Replication in Living Cells Using the ANCHOR DNA Labeling Technology

Autor: Bernard Mariamé, Sandrine Kappler-Gratias, Kerstin Bystricky, Martin Kappler, Stéphanie Balor, Franck Gallardo

Publikováno v: Journal of Virology. 92

Human cytomegalovirus (HCMV) induces latent lifelong infections in all human populations. Between 30% and nearly 100% of individuals are affected depending on the geographic area and socioeconomic conditions. The biology of the virus is difficult to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c818ad39cc07685abcf43fbb353c2be
https://doi.org/10.1128/jvi.00571-18

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Akademický článek

Cycle Sequencing Protocol Using Deep VentR® (exo-) DNA Polymerase and Reduced dNTP and [α-35S]dATP Concentrations

Autor: Bernard Mariamé

Publikováno v: BioTechniques, Vol 21, Iss 1, Pp 18-19 (1996)

Benchmarks are brief communications that describe helpful hints, shortcuts, techniques or substantive modifications of existing methods.

Externí odkaz: https://doaj.org/article/88c4e198a36d422e844f3ac874396e16

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Synthesis and Antiviral Activity Evaluation of Nitroporphyrins and Nitrocorroles as Potential Agents against Human Cytomegalovirus Infection

Autor: Claude P. Gros, Nicolas Desbois, Franck Gallardo, Eloise Demilly, Anne-Françoise Tilkin-Mariamé, Clément Michelin, Bernard Mariamé

Publikováno v: ACS infectious diseases. 1(8)

Different nitroporphyrinoid derivatives were synthesized and studied as potential agents against human Cytomegalovirus. Interestingly, two nitrocorroles display strong activity against human Cytomegalovirus with IC 50 < 0.5 μM. These compounds also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eada4544346199064dc9ef4af98990cd
https://pubmed.ncbi.nlm.nih.gov/27624883

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Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma

Autor: Marie-Laure Renoud, Virginie Robert, Catherine Leclerc, Marilena Djata Cabral, Antoine Magnan, Bruno Gomes, Pierre-Emmanuel Paulet, David Lair, Jean-Charles Guéry, Hans Yssel, Bernard Mariamé, Marc Moreau, Magali Savignac, Lucette Pelletier, Marie Langelot

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 181:1310-1317

Th2 cells orchestrate allergic asthma and the cytokines they produce (IL-4, IL-5, and IL-13) are deleterious in allergy. Therefore, it is important to identify key signaling molecules expressed by Th2 cells that are essential for their function. We h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b809e01845c2bdd688ca896b37b7b03
https://doi.org/10.1164/rccm.200907-1166oc

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No evidence of occult hepatitis C virus (HCV) infection in serum of HCV antibody-positive HCV RNA-negative kidney-transplant patients

Autor: Christophe Pasquier, Jacques Izopet, Nassim Kamar, Lionel Rostaing, Bernard Mariamé, Florence Nicot

Publikováno v: Transplant International. 23:594-601

Persistence of hepatitis C virus (HCV) in patients who cleared HCV is still debated. Occult HCV infection is described as the presence of detectable HCV RNA in liver or peripheral blood mononuclear cells (PBMCs) of patients with undetectable plasma H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a816898a71851670482f63f2658ce8f
https://doi.org/10.1111/j.1432-2277.2009.01025.x

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Melanoma-expressed CD70 is involved in invasion and metastasis

Autor: Iotefa Teiti, Bernard Mariamé, Laurence Lamant, Christine Pich, Philippe Rochaix, Guillaume Sarrabayrouse, Anne-Françoise Tilkin-Mariamé, Gilles Favre, Véronique Maisongrosse

Publikováno v: British Journal of Cancer

Background: CD70 is a costimulatory molecule of the tumour necrosis factor family expressed in activated immune cells and some solid tumours. In lymphocytes CD70 triggers T cell-mediated cytotoxicity and mitogen-activated protein kinase phosphorylati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ba50b625a5ffd2153c2e6e4d5a9575
https://pubmed.ncbi.nlm.nih.gov/26671750

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Coexpression of CD40L and CD70 by semiallogenic tumor cells induces anti-tumor immunity

Autor: Anne-Françoise Tilkin-Mariamé, Carine Cormary, Gilles Favre, Bernard Mariamé, Elsa Hiver

Publikováno v: Cancer Gene Therapy. 12:963-972

The immune system is potentially qualified to detect and eliminate tumor cells, but various mechanisms developed by tumor cells allow tumor escape. Strategies selected to promote antitumor responses have included genetic modifications of tumor cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64883c3967004ee88730b0b16f75160
https://doi.org/10.1038/sj.cgt.7700861

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Rôle de canaux de type L dans la réponse calcique et la production d’interleukine (IL-)4 par les lymphocytes Th2

Autor: Bernard Mariamé, Magali Savignac, Lucette Pelletier, Bruno Gomes

Publikováno v: Journal de la Société de Biologie. 197:259-265

Les lymphocytes T CD4+ sont heterogenes en termes de fonctions et de production de cytokines. Les lymphocytes Th1 produisent de l’IL-2 et de l’interferon IFNy, et sont impliques dans l’elimination des organismes pathogenes intracellulaires. Au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1743b56df204982d1789a6fea38f2f32
https://doi.org/10.1051/jbio/2003197030259

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Epstein-Barr virus late gene transcription depends on the assembly of a virus-specific preinitiation complex

Autor: Fabrice Mure, Bernard Mariamé, Henri Gruffat, Evelyne Manet, Valentin Aubry, Lucjan S. Wyrwicz, Thibaut Deschamps

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2014, 88 (21), pp.12825-12838. ⟨10.1128/JVI.02139-14⟩
Journal of Virology, 2014, 88 (21), pp.12825-12838. ⟨10.1128/JVI.02139-14⟩

During their productive cycle, herpesviruses exhibit a strictly regulated temporal cascade of gene expression that has three general stages: immediate early (IE), early (E), and late (L). Promoter complexity differs strikingly between IE/E genes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912c0c719211243caa84caf55538619
https://pubmed.ncbi.nlm.nih.gov/25165108

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