Zobrazeno 1 - 10
of 491
pro vyhledávání: '"Bernard, Malissen"'
Autor:
Liliana Oliveira, M. Carolina Silva, Ana P. Gomes, Rita F. Santos, Marcos S. Cardoso, Ana Nóvoa, Hervé Luche, Bruno Cavadas, Irina Amorim, Fátima Gärtner, Bernard Malissen, Moisés Mallo, Alexandre M. Carmo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sepsis results from systemic, dysregulated inflammatory responses to infection, culminating in multiple organ failure. Here, we demonstrate the utility of CD5L for treating experimental sepsis caused by cecal ligation and puncture (CLP). We
Externí odkaz:
https://doaj.org/article/b069eaf5d01f4fed8e7e71994fabe4ac
Autor:
Jaime James, Ana Coelho, Gonzalo Fernandez Lahore, Clara M. Hernandez, Florian Forster, Bernard Malissen, Rikard Holmdahl
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 499 (2024)
The positional cloning of single nucleotide polymorphisms (SNPs) of the neutrophil cytosolic factor 1 (Ncf1) gene, advocating that a low oxidative burst drives autoimmune disease, demands an understanding of the underlying molecular causes. A cellula
Externí odkaz:
https://doaj.org/article/b6f6b9445fbb4a14b565b369ca2f7159
Autor:
Fabrice Barlesi, Laurent Gorvel, Daniel Olive, Clemence Demerle, Laurent Greillier, Sonia Pastor, Geoffrey Guittard, Jacques A Nunes, Marielle Mello, Clara Degos, Ana Zarubica, Fabien Angelis, Frédéric Fiore, Bernard Malissen, Hervé Luche
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Tumor necrosis factor superfamily member 14 (TNFRSF14)/herpes virus entry mediator (HVEM) is the ligand for B and T lymphocyte attenuator (BTLA) and CD160-negative immune co-signaling molecules as well as viral proteins. Its expression is
Externí odkaz:
https://doaj.org/article/fdfc15c4c1eb4b6cb203ba727e691a4f
Autor:
Gwenann Cadiou, Tiffany Beauvais, Lucine Marotte, Sylvia Lambot, Cécile Deleine, Caroline Vignes, Malika Gantier, Melanie Hussong, Samuel Rulli, Anne Jarry, Sylvain Simon, Bernard Malissen, Nathalie Labarriere
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immune checkpoint (IC) blockade and adoptive transfer of tumor-specific T-cells (ACT) are two major strategies to treat metastatic melanoma. Their combination can potentiate T-cell activation in the suppressive tumor microenvironment, but the autoimm
Externí odkaz:
https://doaj.org/article/340606cf6c7041f6bba4cce82a0f24d4
Autor:
Kilian Ruminski, Javier Celis-Gutierrez, Nicolas Jarmuzynski, Emilie Maturin, Stephane Audebert, Marie Malissen, Luc Camoin, Guillaume Voisinne, Bernard Malissen, Romain Roncagalli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The propagation and diversification of signals downstream of the T cell receptor (TCR) involve several adaptor proteins that control the assembly of multimolecular signaling complexes (signalosomes). The global characterization of changes in protein-
Externí odkaz:
https://doaj.org/article/5e912809456643aba8f129a48c1cf596
Autor:
Mikel M. Arbulo-Echevarria, Inmaculada Vico-Barranco, Fanghui Zhang, Luis M. Fernandez-Aguilar, Martyna Chotomska, Isaac Narbona-Sánchez, Lichen Zhang, Bernard Malissen, Yinming Liang, Enrique Aguado
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The LAT transmembrane adaptor is essential to transduce intracellular signals triggered by the TCR. Phosphorylation of its four C-terminal tyrosine residues (136, 175, 195, and 235 in mouse LAT) recruits several proteins resulting in the assembly of
Externí odkaz:
https://doaj.org/article/83670c39e1304dc497eced2cd74e5e7d
Autor:
Fumika Honda, Hiroto Tsuboi, Yuko Ono, Saori Abe, Hiroyuki Takahashi, Kiyoaki Ito, Kazunori Yamada, Mitsuhiro Kawano, Yuya Kondo, Kenichi Asano, Masato Tanaka, Marie Malissen, Bernard Malissen, Isao Matsumoto, Takayuki Sumida
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Our previous studies reveal that CCL18-CCR8 chemokine axis is upregulated in patients of immunoglobulin G4-related disease (IgG4-RD), suggesting that the CCL18–CCR8 axis is implicated in the etiology of IgG4-RD, although whether
Externí odkaz:
https://doaj.org/article/c11881d6588845c0bb000ce1e7a6f232
Autor:
Cécile Apert, Ariel O. Galindo-Albarrán, Sarah Castan, Claire Detraves, Héloise Michaud, Nicola McJannett, Bart Haegeman, Simon Fillatreau, Bernard Malissen, Georg Holländer, Saulius Žuklys, Jérémy C. Santamaria, Olivier P. Joffre, Paola Romagnoli, Joost P. M. van Meerwijk
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Development of Foxp3-expressing regulatory T-lymphocytes (Treg) in the thymus is controlled by signals delivered in T-cell precursors via the TCR, co-stimulatory receptors, and cytokine receptors. In absence of IL-2, IL-15 or their receptors, fewer T
Externí odkaz:
https://doaj.org/article/99c45be99e5148a1b68f7c4d8d930a42
Autor:
Jessica Filtjens, Anais Roger, Linda Quatrini, Elisabeth Wieduwild, Jordi Gouilly, Guillaume Hoeffel, Rafaëlle Rossignol, Clara Daher, Guilhaume Debroas, Sandrine Henri, Claerwen M. Jones, Bernard Malissen, Laura K. Mackay, Aziz Moqrich, Francis R. Carbone, Sophie Ugolini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Herpes simplex virus 1 (HSV-1) is a neurotropic virus that often cause pain via the induction of ulcer or blisters. Here the authors show, in mouse models of HSV-1 infection, that the pain-perceiving nociceptor Nav1.8 + neurons contribute to regulati
Externí odkaz:
https://doaj.org/article/42a3ec0604df491d8f51a1b9be9121c7
Autor:
Liaoxun Lu, Tianhan Li, Xinyu Feng, Zhilong Liu, Yang Liu, Tianzhu Chao, Yanrong Gu, Rong Huang, Fanghui Zhang, Le He, Binhui Zhou, Eryan Kong, Zhuangzhuang Liu, Xugang Wang, Zhijun Chen, Hui Wang, Marie Malissen, Bernard Malissen, Lichen Zhang, Yinming Liang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010596 (2022)
Schistosomiasis is caused by parasitic flatworms known as schistosomes and affects over 200 million people worldwide. Prevention of T cell exhaustion by blockade of PD-1 results in clinical benefits to cancer patients and clearance of viral infection
Externí odkaz:
https://doaj.org/article/178507c05552464c9b4cb01608abcea8