Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Bernard, Malfoy"'
Autor:
Khuong Truong, Jack Boenders, Zofia Maciorowski, Philippe Vielh, Bernard Dutrillaux, Bernard Malfoy, Claire A. Bourgeois
Publikováno v:
Analytical Cellular Pathology, Vol 13, Iss 3, Pp 137-146 (1997)
The purpose of this study was to improve the detection of FISH signals, in order that spot counting by a fully automated image cytometer be comparable to that obtained visually under the microscope. Two systems of spot scoring, visual and automated c
Externí odkaz:
https://doaj.org/article/fb5005a908c348ea8c3ef1fc1d015f54
Autor:
Nicolas Vogt, Anne Gibaud, Anna Almeida, Isabelle Ourliac-Garnier, Michelle Debatisse, Bernard Malfoy
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14249 (2010)
BACKGROUND: Gene amplification is thought to promote over-expression of genes favouring tumour development. Because amplified regions are usually megabase-long, amplification often concerns numerous syntenic or non-syntenic genes, among which only a
Externí odkaz:
https://doaj.org/article/a7d4f9b9ff89476b8a629806912d5607
Autor:
Nabila-Sandra Hadj-Hamou, Bahar Sanli-Bonazzi, Michaela Nathrath, Michael J. Atkinson, Christine Rümenapp, Iria Gonzalez-Vasconcellos, Michael Rosemann, Daniel Baumhoer, Bernard Malfoy, Jan Smida
Publikováno v:
Curr. Genomics 13, 433-437 (2012)
ResearcherID
Current Genomics
ResearcherID
Current Genomics
Secondary bone tumours arising in the field of a preceding radiotherapy are a serious late effect, in particular considering the increasing survival times in patients treated for paediatric malignancies. In general, therapy associated tumours are kno
Autor:
Bernard Malfoy, Anne Gibaud, Nabila-Sandra Hadj-Hamou, Philippe Hupé, Michelle Debatisse, Jean-Philippe Meyniel, Nicolas Vogt
Publikováno v:
Human Molecular Genetics. 19:1276-1285
Accumulation of extrachromosomal DNA molecules (double minute) is often responsible for gene amplification in cancers, but the mechanisms leading to their formation are still largely unknown. By using quantitative PCR, chromosome walking, in situ hyb
Autor:
Mathilde Huygue, Xavier Sastre-Garau, Anne Gibaud, Sandrine Lefevre, Nathalie Gonin-Laurent, Livia Lumbroso, François Doz, Morgane Le Bras, Laurent Chauveinc, Sylvie Chevillard, Bernard Malfoy
Publikováno v:
Carcinogenesis. 27:1266-1272
The mutagenic properties of ionizing radiation are well known, but the presence of specific mutations in human radiation-induced tumours is not established. We have studied a series of 36 secondary sarcomas arising in the irradiation field of a prima
Autor:
Michelle Debatisse, Anne Gibaud, Nicolas Vogt, Bernard Malfoy, Frédéric Lemoine, Pierre de la Grange
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2014, 42 (21), pp.13194-13205. ⟨10.1093/nar/gku1101⟩
Nucleic Acids Research, Oxford University Press, 2014, 42 (21), pp.13194-13205. ⟨10.1093/nar/gku1101⟩
Nucleic Acids Research, 2014, 42 (21), pp.13194-13205. ⟨10.1093/nar/gku1101⟩
Nucleic Acids Research, Oxford University Press, 2014, 42 (21), pp.13194-13205. ⟨10.1093/nar/gku1101⟩
International audience; The mechanisms of gene amplification in tumour cells are poorly understood and the relationship between extrachromosomal DNA molecules, named double minutes (dmins), and intrachromosomal homogeneously staining regions (hsr) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e58275f24eb8d5c4833901b561598a
https://hal.sorbonne-universite.fr/hal-01332776/document
https://hal.sorbonne-universite.fr/hal-01332776/document
Autor:
Bernard Malfoy, Dat Tran, Brad A. Bryan, Kundan Verma, Dolores Diaz, Anna Almeida, Dianne C. Mitchell, Eva W. Stratford, Esha Kataria, Alireza Torabi, Kristin Ward
Publikováno v:
The American journal of pathology. 185(3)
Liposarcomas, which are malignant fatty tumors, are the second most common soft-tissue sarcomas. Several histologically defined liposarcoma subtypes exist, yet little is known about the molecular pathology that drives the diversity in these tumors. W
Publikováno v:
Cancer Research. 70:P6-08
Background: Secondary angiosarcoma of the breast is defined as a sarcoma developed in the irradiated field in patients previously treated for breast carcinoma. These tumors represent 25% to 50% of sarcomas developed after irradiation for breast cance
Autor:
Jerzy Klijanienko, Khuong Truong, Bernard Malfoy, Bernard Dutrillaux, Philippe Vielh, Claire A. Bourgeois
Publikováno v:
Cancer. 84:309-316
BACKGROUND Automated image cytometry can allow concurrent quantification of several parameters in each individual cell within a population, opening new possibilities for diagnosis and prognosis. In this study, the authors investigated the capacity of
Autor:
Anne Marie Dutrillaux, Bernard Dutrillaux, Rachana Tyagi, Martine Muleris, Anna Almeida, Xiang Xiao Zhu, Donald A. Ross, Samir M. Hanash, Nicolas Vogt, Bernard Malfoy
Publikováno v:
Oncogene. 16:2997-3002
We have used two-dimensional electrophoresis of enzyme-digested genomic DNA to identify a novel gene GAC1, which maps at 1q32.1 and which is overexpressed in malignant gliomas in which it is amplified. GAC1 encodes a protein which belongs to the leuc