Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Bernard, Gilquin"'
Autor:
Arhamatoulaye Maïga, Jon Merlin, Elodie Marcon, Céline Rouget, Maud Larregola, Bernard Gilquin, Carole Fruchart-Gaillard, Evelyne Lajeunesse, Charles Marchetti, Alain Lorphelin, Laurent Bellanger, Roger J Summers, Dana S Hutchinson, Bronwyn A Evans, Denis Servent, Nicolas Gilles
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68841 (2013)
ρ-Da1a is a three-finger fold toxin from green mamba venom that is highly selective for the α1A-adrenoceptor. This toxin has atypical pharmacological properties, including incomplete inhibition of (3)H-prazosin or (125)I-HEAT binding and insurmount
Externí odkaz:
https://doaj.org/article/ea1b5de2a53b4c798bdec40a54b07f16
Autor:
Emeline Vernhes, Madalena Renouard, Bernard Gilquin, Philippe Cuniasse, Dominique Durand, Patrick England, Sylviane Hoos, Alexis Huet, James F. Conway, Anatoly Glukhov, Vladimir Ksenzenko, Eric Jacquet, Naïma Nhiri, Sophie Zinn-Justin, Pascale Boulanger
Publikováno v:
Scientific Reports
Scientific Reports, 2017, 7, pp.43977. ⟨10.1038/srep43977⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.43977. ⟨10.1038/srep43977⟩
Scientific Reports, 2017, 7, pp.43977. ⟨10.1038/srep43977⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.43977. ⟨10.1038/srep43977⟩
Scientific Reports 7: Article number: 41662; published online: 06 February 2017; updated: 28 April 2017 This Article contains typographical errors. In the results section under subheading ‘The C-terminal domain adopts an immunoglobulin fold in solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48be9dcddef2900393467dea8b6d0fa7
https://doi.org/10.1038/srep43977
https://doi.org/10.1038/srep43977
Autor:
Bernard Gilquin, Benjamin Chagot, Paulo Tavares, Matthieu Gallopin, I. Petitpas, Isabelle Auzat, Sophie Zinn-Justin
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 80:319-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57577511eed5c67f97922dc0d5d15905
https://doi.org/10.1002/prot.23191
https://doi.org/10.1002/prot.23191
Autor:
Denis Servent, Elodie Marcon, Gilles Mourier, André Ménez, Guillaume Letellier, Bernard Gilquin, Carole Fruchart-Gaillard, Sophie Zinn-Justin, Catherine Marquer
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (36), pp.31661-31675. ⟨10.1074/jbc.M111.261404⟩
Journal of Biological Chemistry, 2011, 286 (36), pp.31661-31675. ⟨10.1074/jbc.M111.261404⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (36), pp.31661-31675. ⟨10.1074/jbc.M111.261404⟩
Journal of Biological Chemistry, 2011, 286 (36), pp.31661-31675. ⟨10.1074/jbc.M111.261404⟩
International audience; The snake toxin MT7 is a potent and specific allosteric modulator of the human M1 muscarinic receptor (hM1). We previously characterized by mutagenesis experiments the functional determinants of the MT7-hM1 receptor interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228e2dd27884389384b34fea3e6da89f
https://doi.org/10.1074/jbc.m111.261404
https://doi.org/10.1074/jbc.m111.261404
Autor:
Marie Hélène Le Du, Henrik Gårdsvoll, André Ménez, Michael Ploug, Thomas J. D. Jørgensen, Bernard Gilquin
Publikováno v:
Journal of Biological Chemistry. 281:19260-19272
The high affinity interaction between the serine protease urokinase-type plasminogen activator (uPA) and its glycolipid-anchored receptor (uPAR) represents one of the key regulatory steps in cell surface-associated plasminogen activation. On the basi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50d609d03cd8602ae3c82252c30dff68
https://doi.org/10.1074/jbc.m513583200
https://doi.org/10.1074/jbc.m513583200
Autor:
Paola Llinas, Keld Danø, Henrik Gårdsvoll, André Ménez, Michael Ploug, Enrico A. Stura, Bernard Gilquin, Marie Hélène Le Du
Publikováno v:
The EMBO Journal. 24:1655-1663
We report the crystal structure of a soluble form of human urokinase-type plasminogen activator receptor (uPAR/CD87), which is expressed at the invasive areas of the tumor-stromal microenvironment in many human cancers. The structure was solved at 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f7c44bf96469f27e6b34343f55d602
https://doi.org/10.1038/sj.emboj.7600635
https://doi.org/10.1038/sj.emboj.7600635
Autor:
Bernard Gilquin, Eric Quéméneur, Sophie Zinn-Justin, Isabelle Callebaut, Gaëlle Charier, Raphael Guerois, Béatrice Alpha-Bazin, Joël Couprie, Vincent Meyer
Publikováno v:
Structure. 12:1551-1562
53BP1 is a key transducer of the DNA damage checkpoint signal, which is required for phosphorylation of a subset of ATM substrates and p53 accumulation. After cell irradiation, the 53BP1 N-terminal region is phosphorylated. Its two C-terminal BRCT mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2aa5584c4323e68dedeb9c1c1844aaa
https://doi.org/10.1016/j.str.2004.06.014
https://doi.org/10.1016/j.str.2004.06.014
Autor:
Bernard Gilquin, André Ménez, Marjorie Bourgoin, Sophie Zinn-Justin, Denis Servent, Renée Ménez, Marie-Hélène Le Du
Publikováno v:
Protein Science
Protein Science, 2003, 12 (2), pp.266-277. ⟨10.1110/ps.0227703⟩
Protein Science, 2003, 12 (2), pp.266-277. ⟨10.1110/ps.0227703⟩
Animal toxins are small proteins built on the basis of a few disulfide bonded frameworks. Because of their high variability in sequence and biologic function, these proteins are now used as templates for protein engineering. Here we report the extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81ce5ce4a6a0a7c976bf87ff94408f0
https://doi.org/10.1110/ps.0227703
https://doi.org/10.1110/ps.0227703
Autor:
Bernard Gilquin
Publikováno v:
La Presse Médicale. 41:749-751
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca37cf5bfb9549f0b0267f5910c61cd0
https://doi.org/10.1016/j.lpm.2011.10.030
https://doi.org/10.1016/j.lpm.2011.10.030
Autor:
Anja Wrisch, Bernard Gilquin, Judith Racapé, André Ménez, Stephan Grissmer, Sylvaine Gasparini, Alain Lecoq, Violeta Visan
Publikováno v:
Journal of Biological Chemistry. 277:37406-37413
A structural model of BgK, a sea anemone toxin, complexed with the S5-S6 region of Kv1.1, a voltage-gated potassium channel, was determined by flexible docking under distance restraints identified by a double mutant cycles approach. This structure pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b08277bb6a3dc242c3098f32beccd2
https://doi.org/10.1074/jbc.m206205200
https://doi.org/10.1074/jbc.m206205200