Structural and functional characterization of the IpaD π-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence

Autor: Barker, Samuel A., Bernard, Abram R., Morales, Yalemi, Johnson, Sean J., Dickenson, Nicholas E.

Publikováno v: In Journal of Biological Chemistry September 2024 300(9)

Investigation of the Molecular Mechanisms of the Shigella Type III Secretion System Tip Complex

Autor: Bernard, Abram R.

Publikováno v: All Graduate Theses and Dissertations.

Shigella are bacteria that are responsible for millions of infections and hundreds of thousands of deaths every year. The emergence of antibiotic resistant Shigella adds to the potentially devastating effect that these bacteria can have on human heal

Externí odkaz: https://digitalcommons.usu.edu/etd/7373
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=8490&context=etd

Deoxycholate-Enhanced Shigella Virulence Is Regulated by a Rare π-Helix in the Type Three Secretion System Tip Protein IpaD.

Autor: Bernard, Abram R., Jessop, T. Carson, Kumar, Prashant, Dickenson, Nicholas E.

Publikováno v: Biochemistry; 12/12/2017, Vol. 56 Issue 49, p6503-6514, 12p

Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.

Autor: Demler HJ; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah., Case HB; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah., Morales Y; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah., Bernard AR; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah., Johnson SJ; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah., Dickenson NE; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah.

Publikováno v: Proteins [Proteins] 2019 Nov; Vol. 87 (11), pp. 931-942. Date of Electronic Publication: 2019 Jun 21.