Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bernadette Tasiaux"'
Autor:
Anna Doshina, Florian Gourgue, Michiho Onizuka, Remi Opsomer, Peng Wang, Kunie Ando, Bernadette Tasiaux, Ilse Dewachter, Pascal Kienlen-Campard, Jean-Pierre Brion, Philippe Gailly, Jean-Noël Octave, Nathalie Pierrot
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride con
Externí odkaz:
https://doaj.org/article/17df00cf26f446d68bc775b9993f6c1a
Autor:
Caroline Evrard, Pascal Kienlen-Campard, Mathilde Coevoet, Rémi Opsomer, Bernadette Tasiaux, Patricia Melnyk, Jean-Noël Octave, Luc Buée, Nicolas Sergeant, Valérie Vingtdeux
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Aβ peptides, the major components of Alzheimer’s disease (AD) amyloid deposits, are released following sequential cleavages by secretases of its precursor named the amyloid precursor protein (APP). In addition to secretases, degradation pathways,
Externí odkaz:
https://doaj.org/article/2633ffaf0c1f45a6a5fa8fc69f8a5625
Autor:
Serena Stanga, Liliana Brambilla, Bernadette Tasiaux, Anh H. Dang, Adrian Ivanoiu, Jean-Noël Octave, Daniela Rossi, Vincent van Pesch, Pascal Kienlen-Campard
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
The current inability of clinical criteria to accurately identify the “at-risk group” for Amyotrophic Lateral Sclerosis (ALS) development as well as its unknown etiology are fueling the interest in biomarkers aimed at completing clinical approach
Externí odkaz:
https://doaj.org/article/265cd9fd89fa4895a200885e095db5a2
Autor:
Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Pascal Kienlen-Campard, Charles De Smet, Jean-Noël Octave
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99467 (2014)
We previously demonstrated that APP epigenetically regulates Egr1 expression both in cultured neurons and in vivo. Since Egr1 is an immediate early gene involved in memory formation, we wondered whether other early genes involved in memory were regul
Externí odkaz:
https://doaj.org/article/dd3dfe41811e4d5da101ca30e0c5abb2
Autor:
Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Jean-Pierre Brion, Pascal Kienlen-Campard, Charles De Smet, Jean-Noël Octave
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74305 (2013)
Following transcriptome comparison of primary cultures isolated from brain of mice expressing or not the amyloid precursor protein APP, we found transcription of the EGR-1 gene to be regulated by APP. In primary cultures of cortical neurons, APP sign
Externí odkaz:
https://doaj.org/article/1835fd213cf043459ae1e2b7bbf55dd1
Autor:
Céline Vrancx, Pierre J. Doyen, Bernadette Tasiaux, Serena Stanga, Maxime Vergouts, Pascal Kienlen-Campard, Roberta Gualdani, Nathalie Pierrot, Philippe Gailly, Jean-Noël Octave, Anna Doshina, Rémi Opsomer, Florian Perrin, Sabrina Contino
Publikováno v:
eNeuro, Vol. 7, no. 3, p. ENEURO.0322-19.202 [1-18] (2020)
eNeuro
eNeuro
Visual Abstract
The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the
The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177f160d38cf853ee72492a0b42d18a3
https://hdl.handle.net/2078.1/230453
https://hdl.handle.net/2078.1/230453
Autor:
Serena Stanga, Claudia Marinangeli, Bernadette Tasiaux, Céline Vrancx, Pascal Kienlen-Campard, Helena Karlström
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Vol. 22, no. 2, p. 823-833 (2018)
Journal of Cellular and Molecular Medicine, Vol. 22, no. 2, p. 823-833 (2018)
The two presenilin‐1 (PS1) and presenilin‐2 (PS2) homologs are the catalytic core of the γ‐secretase complex, which has a major role in cell fate decision and Alzheimer's disease (AD) progression. Understanding the precise contribution of PS1
Autor:
Doyen P, Bernadette Tasiaux, Pascal Kienlen-Campard, Jean-Noël Octave, Vergouts M, Nathalie Pierrot, Rémi Opsomer, Serena Stanga, Florian Perrin, Sabrina Contino, Anna Doshina, Céline Vrancx
Sequential proteolysis of the amyloid precursor protein (APP) and amyloid-β peptide (Aβ) release is an upstream event in Alzheimer’s disease (AD) pathogenesis. The function of APP in neuronal physiology is still, however, poorly understood. Along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1733b32a355feec3cfc5b5a1e874f70
https://doi.org/10.1101/504340
https://doi.org/10.1101/504340
Autor:
Bernadette Tasiaux, Pascal Kienlen-Campard, Rémi Opsomer, Valérie Vingtdeux, Caroline Evrard, Luc Buée, Jean-Noël Octave, Nicolas Sergeant
Aβ peptides, the major components of amyloid deposits of Alzheimer’s disease, are released following sequential cleavages by secretases of its precursor named the amyloid precursor protein (APP). In addition to secretases, degradation pathways, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f789546832051c65a3a8586279b6ea79
Autor:
Daniela Rossi, Pascal Kienlen-Campard, Anh H. Dang, Jean-Noël Octave, Vincent Van Pesch, Adrian Ivanoiu, Bernadette Tasiaux, Serena Stanga, Liliana Brambilla
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Frontiers in Neurology
Frontiers in neurology, Vol. 9, p. 384 [1-9] (2018)
Frontiers in Neurology
Frontiers in neurology, Vol. 9, p. 384 [1-9] (2018)
The current inability of clinical criteria to accurately identify the “at-risk group” for Amyotrophic Lateral Sclerosis (ALS) development as well as its unknown etiology are fueling the interest in biomarkers aimed at completing clinical approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e635321d6fea4d23225fc3b77f2f01ef
http://hdl.handle.net/2318/1717291
http://hdl.handle.net/2318/1717291