Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Bernadette O Fernandez"'
Autor:
Jia L. Stevens, Helen T. McKenna, Helder Filipe, Laurie Lau, Bernadette O. Fernandez, Andrew J. Murray, Martin Feelisch, Daniel S. Martin
Publikováno v:
Perioperative Medicine, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract Background Tissue injury induces inflammation and the surgical stress response, which are thought to be central to the orchestration of recovery or deterioration after surgery. Enhanced formation of reactive oxygen and nitrogen species accom
Externí odkaz:
https://doaj.org/article/419775ee06ed4fb197582603ec361a9e
Autor:
Philip J. Hennis, Andrew F. Cumpstey, Alasdair F. O’Doherty, Bernadette O. Fernandez, Edward T. Gilbert-Kawai, Kay Mitchell, Helen Moyses, Alexandra Cobb, Paula Meale, Helmut Pöhnl, Monty G. Mythen, Michael P. W. Grocott, Denny Z. H. Levett, Daniel S. Martin, Martin Feelisch, The Xtreme Alps Research Group, Adam Booth, Adam Sheperdigian, Alasdair O’Doherty, Alex Salam, Andrew Cumpstey, Bernadette Fernandez, Damian Mole, Daniel Grant, Daniel Martin, Denny Levett, Edith Kortekaas, Edward Gilbert, Fabio Rigat, Fiona Shrubb, Heng Yow, James Farrant, Jildou van der Kaaij, Jim Milledge, Jo Simpson, Laura Jackson, Liesl Wandrag, Lindsay Bisiker, Mark Edsell, Maryam Khosravi, Matt Sanborn, Michael Grocott, Michael Mythen, Nick Talbot, Oliver Burdall, Oliver Firth, Oliver Moses, Phil Hennis, Savini Wijesingha, Steve Dauncey, Tom Adams, Tom Woolley, Wilby Williamson, Will Jenner, Zeyn Mahomed
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
IntroductionNitrate supplementation in the form of beetroot juice (BRJ) ingestion has been shown to improve exercise tolerance during acute hypoxia, but its effect on exercise physiology remains unstudied during sustained terrestrial high altitude ex
Externí odkaz:
https://doaj.org/article/5874770ad0244740b9422554efa5fad6
Autor:
Helen T. McKenna, Katie A. O'Brien, Bernadette O. Fernandez, Magdalena Minnion, Adam Tod, Ben D. McNally, James A. West, Julian L. Griffin, Michael P. Grocott, Michael G. Mythen, Martin Feelisch, Andrew J. Murray, Daniel S. Martin
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101907- (2021)
Background: Numerous pathologies result in multiple-organ failure, which is thought to be a direct consequence of compromised cellular bioenergetic status. Neither the nature of this phenotype nor its relevance to survival are well understood, limiti
Externí odkaz:
https://doaj.org/article/9c66267adf404de2a8e691584df51551
Autor:
Anna Freeman, Doriana Cellura, Magdalena Minnion, Bernadette O. Fernandez, Cosma Mirella Spalluto, Denny Levett, Andrew Bates, Timothy Wallis, Alastair Watson, Sandy Jack, Karl J. Staples, Michael P. W. Grocott, Martin Feelisch, Tom M. A. Wilkinson
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1926 (2021)
Redox dysregulation and oxidative stress have been implicated in asthma pathogenesis. Exercise interventions improve symptoms and reduce inflammation in asthma patients, but the underlying mechanisms remain unclear. We hypothesized that a personalise
Externí odkaz:
https://doaj.org/article/6966a5e69d804666a0b1f3956220dc2a
Autor:
Melanie Reijrink, Stefanie A. De Boer, Anniek M. Van Roon, Riemer H. J. A. Slart, Bernadette O. Fernandez, Martin Feelisch, Hiddo J. L. Heerspink, Harry Van Goor, Jan-Luuk Hillebrands, Douwe J. Mulder
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1548 (2021)
The depletion of nitrate and nitrite, stable nitric oxide (NO) end-products, promotes adipose tissue dysfunction and insulin resistance (IR). Dipeptidyl peptidase-4 (DPP-4) inhibitors have the potentially beneficial side effect of increasing NO avail
Externí odkaz:
https://doaj.org/article/245640b5184e499d897ac221f5c41e0c
Autor:
Liesl Wandrag, Mario Siervo, Heather L. Riley, Maryam Khosravi, Bernadette O. Fernandez, Carl A. Leckstrom, Daniel S. Martin, Kay Mitchell, Denny Z.H. Levett, Hugh E. Montgomery, Monty G. Mythen, Michael A. Stroud, Michael P.W. Grocott, Martin Feelisch
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 60-68 (2017)
Objectives: Sarcopenia refers to the involuntary loss of skeletal muscle and is a predictor of physical disability/mortality. Its pathogenesis is poorly understood, although roles for altered hypoxic signaling, oxidative stress, adipokines and inflam
Externí odkaz:
https://doaj.org/article/16dbe4da3b5d4bd58a73af9f4a9f58bd
Autor:
Julian O.M. Ormerod, MD, PhD, Jonathan D.W. Evans, MD, Hussain Contractor, MD, PhD, Matteo Beretta, PhD, Sayqa Arif, MD, PhD, Bernadette O. Fernandez, PhD, Martin Feelisch, PhD, Bernd Mayer, PhD, Rajesh K. Kharbanda, MD, PhD, Michael P. Frenneaux, MD, Houman Ashrafian, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 1, Pp 13-21 (2017)
Summary: Pre-conditioning is an exciting physiological phenomenon that, despite great efforts, has so far resisted translation to mainstream clinical medicine. Many potential triggers (e.g., ischemia of the organ in question or a remote organ, many d
Externí odkaz:
https://doaj.org/article/e36113c5ea4b41e6a0330111aed667ce
Autor:
Amaal Eman Abdulle, Anniek M. van Roon, Andries J. Smit, Andreas Pasch, Matijs vanMeurs, Hendrika Bootsma, Stephan J. L. Bakker, Mohammad Y. Said, Bernadette O. Fernandez, Martin Feelisch, Harry vanGoor, Douwe J. Mulder
Publikováno v:
Physiological Reports, Vol 7, Iss 6, Pp n/a-n/a (2019)
Abstract Raynaud's phenomenon (RP) is often the first sign of systemic sclerosis (SSc). Molecular mechanisms involved are incompletely understood, but reactive oxygen, nitrogen, and sulfur species are thought to play an important role in the pathogen
Externí odkaz:
https://doaj.org/article/b826253d0bca4f4fa02b5b491b07225e
Autor:
Andrew F. Cumpstey, Magdalena Minnion, Bernadette O. Fernandez, Monika Mikus-Lelinska, Kay Mitchell, Daniel S. Martin, Michael P.W. Grocott, Martin Feelisch
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
The chemical and functional interactions between Reactive Oxygen (ROS), Nitrogen (RNS) and Sulfur (RSS) species allow organisms to detect and respond to metabolic and environmental stressors, such as exercise and altitude exposure. Whether redox mark
Externí odkaz:
https://doaj.org/article/4f44156f38eb4800a340f8f913540863
Autor:
Jia L Stevens, Helen T McKenna, Helder Filipe BSc, Laurie Lau, Bernadette O Fernandez, Andrew J Murray, Martin Feelisch, Daniel S Martin
Background Tissue injury induces inflammation and the surgical stress response, which are thought to be central to the orchestration of recovery or deterioration after surgery. Enhanced formation of reactive oxygen and nitrogen species accompanies th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::880089e2f15c3f2cd34dc13d4e4968bb
https://doi.org/10.21203/rs.3.rs-2577239/v1
https://doi.org/10.21203/rs.3.rs-2577239/v1