Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bernadette M. Glasheen"'
Autor:
Jennifer A. Suggs, Girish C. Melkani, Bernadette M. Glasheen, Mia M. Detor, Anju Melkani, Nathan P. Marsan, Douglas M. Swank, Sanford I. Bernstein
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 6, Pp 761-771 (2017)
Individuals with inclusion body myopathy type 3 (IBM3) display congenital joint contractures with early-onset muscle weakness that becomes more severe in adulthood. The disease arises from an autosomal dominant point mutation causing an E706K substit
Externí odkaz:
https://doaj.org/article/0734f576d32c4449a6e56f15badb6a57
Publikováno v:
Am J Physiol Cell Physiol
A muscle undergoing cyclical contractions requires fast and efficient muscle activation and relaxation to generate high power with relatively low energetic cost. To enhance activation and increase force levels during shortening, some muscle types hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0949744d58fe0a1e8cba6bb6e3eb4e4
https://pubmed.ncbi.nlm.nih.gov/34965153
https://pubmed.ncbi.nlm.nih.gov/34965153
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61907d9ca9b8284e10dbc85a437bfa9e
https://doi.org/10.1096/fasebj.2022.36.s1.r2445
https://doi.org/10.1096/fasebj.2022.36.s1.r2445
Autor:
Bernadette M. Glasheen, Seemanti Ramanath, Monica Patel, Joy T. Puthawala, Debra Sheppard, Lauren Riley, Douglas M. Swank
Publikováno v:
Biophysical Journal. 114:1142-1152
Muscles have evolved to power a wide variety of movements. A protein component critical to varying power generation is the myosin isoform present in the muscle. However, how functional variation in muscle arises from myosin structure is not well unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4c755ec30dd454211de27aa2a139b1
https://doi.org/10.1016/j.bpj.2017.12.045
https://doi.org/10.1016/j.bpj.2017.12.045
Publikováno v:
Biophysical Journal. 116:177a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ee95e2d40493387369f23469320152
https://doi.org/10.1016/j.bpj.2018.11.983
https://doi.org/10.1016/j.bpj.2018.11.983
Autor:
Bernadette M. Glasheen, Girish C. Melkani, Madhulika Achal, Sanford I. Bernstein, Anthony Cammarato, Rolf Bodmer, Jennifer A. Suggs, Anju Melkani, Douglas M. Swank, Meera C. Viswanathan, Karen Ocorr, Gaurav Kaushik, Adriana S. Trujillo, Gerrie P. Farman, Christopher S. Newhard, Jeffrey R. Moore
An "invariant proline" separates the myosin S1 head from its S2 tail and is proposed to be critical for orienting S1 during its interaction with actin, a process that leads to muscle contraction. Mutation of the invariant proline to leucine (P838L) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afafd919fa9669117b14bf4e7d6a44bb
https://europepmc.org/articles/PMC4884507/
https://europepmc.org/articles/PMC4884507/
Publikováno v:
Proceedings of the National Academy of Sciences. 106:2659-2664
Human matrix metalloproteinases (MMPs) are believed to contribute to tumor progression. Therapies based on inhibiting the catalytic domain of MMPs have been unsuccessful, but these studies raise the question of whether other MMP domains might be appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02a037c6c72efb3ab52a653d4a863bb
https://doi.org/10.1073/pnas.0804171106
https://doi.org/10.1073/pnas.0804171106
Autor:
Bruce B. Clarke, Jo Anne Crouch, Bradley I. Hillman, Michael A. Giunta, Bernadette M. Glasheen
Publikováno v:
Fungal Genetics and Biology. 45:190-206
Mobile transposable elements are among the primary drivers of the evolution of eukaryotic genomes. For fungi, repeat-induced point mutation (RIP) silencing minimizes deleterious effects of transposons by mutating multicopy DNA during meiosis. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e9cf80f7c8820729694f8bd8db960f
https://doi.org/10.1016/j.fgb.2007.08.004
https://doi.org/10.1016/j.fgb.2007.08.004
Autor:
Lauren Riley, Douglas M. Swank, Debra Sheppard, Bernadette M. Glasheen, Christopher S. Newhard
Publikováno v:
Biophysical Journal. 108(2)
The myosin converter has been proposed to be critical for setting muscle shortening velocity by influencing the amplification of small conformational changes at the ATPase site into the larger lever arm swing. To test this hypothesis, we exploited th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa6b99a3f30483f9e68a0b8608b694b
Autor:
D. C. Ramsdell, James J. Polashock, Bernadette M. Glasheen, J. M. Gillett, Bradley I. Hillman, Diane M. Lawrence, N. Vorsa
Publikováno v:
Archives of Virology. 147:2169-2186
The double-stranded DNA genome of Blueberry red ringspot virus (BRRV), a member of the family Caulimoviridae, was cloned and sequenced. The genome organization and relationships of the 8303 nt sequence revealed BRRV to be a tentative member of the ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35481bf957c8d41d2d7e639d8e881ef
https://doi.org/10.1007/s00705-002-0866-7
https://doi.org/10.1007/s00705-002-0866-7