Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bernadette M. Allison"'
Autor:
David H. Moore, Bernadette M. Allison, Robert M. Bigsby, Jean A. Hurteau, William Hurd, Katherine Y. Look, Gregory P. Sutton
Publikováno v:
Cancer. 85:1810-1815
BACKGROUND Transforming growth factor-β (TGF-β) is known to inhibit primary epithelial ovarian carcinoma cells. The mechanism by which this inhibitory response is achieved is poorly understood. Furthermore, whether this response is consistent in ce
Autor:
Robert M. Bigsby, Katherine Y. Look, Gregory P. Sutton, David H. Moore, Bernadette M. Allison
Publikováno v:
Gynecologic Oncology. 65:78-82
Background: There are several distinct forms of the matrix metalloproteinases (MMP) that degrade collagen in the extracellular matrix. Most involved in the metastatic process are collagenases exhibiting specificity for type IV collagen, the collagen
Autor:
Eric A. Benson, Mark G. Goebl, Bernadette M. Allison, E. Vig-Varga, Maureen A. Harrington, Tony L. Limbil
Publikováno v:
Gynecologic oncology. 103(1)
Objective. The intracellular redox state plays an important role in controlling inflammation. Clinical and laboratory data suggest that inflammation can lead to tumor progression. We hypothesized that restoring intracellular redox control would inhib
Autor:
Mark G. Goebl, Susan A. Brutkiewicz, Jean A. Hurteau, Maureen A. Harrington, Bernadette M. Allison, Qi Wang
Publikováno v:
Gynecologic oncology. 86(1)
Objective. The purpose of this study was to test the hypothesis that the expression of the mutant p27 Kip1 protein enhances cell growth inhibition and is more stable than that of the wild-type p27 Kip1 . Methods. Site-directed mutagenesis was used to
Autor:
Susan A. Brutkiewicz, Douglas K. Heilman, Bernadette M. Allison, Mark G. Goebl, Jean A. Hurteau, Maureen A. Harrington, Robert M. Bigsby
Publikováno v:
Gynecologic oncology. 83(2)
To determine if p27(Kip1) expression was altered in epithelial ovarian cancers as compared to normal ovarian surface epithelial (NOSE) cells and to determine if subcellular localization of p27(Kip1) was an important feature.Thirteen tumor samples (1